Results 21 to 30 of about 15,006 (243)

Panton-Valentine Leukocidin in Necrotizing Pneumonia: A Case Report. [PDF]

Cureus
Panton-Valentine leukocidin (PVL)-producing Staphylococcus aureus (S. aureus) is a rare but clinically significant cause of community-acquired pneumonia (CAP). This toxin leads to extensive tissue destruction and severe inflammation, often progressing to necrotizing pneumonia, septic shock, and multiorgan failure, representing a challenge in medical ...
Costa CA, Inácio H, Trevas S, Simas Â.
europepmc   +3 more sources

Involvement of Panton-Valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia.

Clinical Infectious Diseases, 1999
G. Lina, Y. Piémont, Florence Godail-Gamot, M. Bes, M. Peter, V. Gauduchon, F. Vandenesch, J. Etienne   +7 more
semanticscholar   +3 more sources

Necrotizing Pneumonia Caused by PVL-Negative Methicillin-Susceptible <i>Staphylococcus aureus</i> Complicated by Refractory Pneumothorax: A Case Report. [PDF]

Respirol Case Rep
Here we report a case of PVL‐negative MSSA necrotizing pneumonia in a previously healthy man that rapidly progressed to cavitary lesions and refractory pneumothorax. Despite its improvement after clindamycin‐based therapy, the patient experienced recurrent pneumothorax and chronic respiratory failure.
Endo S, Yasuda T, Izumi M, Shimaya K, Tsukada Y.   +4 more
europepmc   +2 more sources

Panton-Valentine leukocidin (PVL) [PDF]

Okayama Igakkai Zasshi (Journal of Okayama Medical Association), 2007
Cribier G, Prevost G, Couppie P, Fi, Etienne J, Genestier AL, Michallet MC, Prevost, GILLET Y, MIYASHITA T, Panton PN, Valentine FCO, Prevost G, Cribier B, Couppie P, et, Valentine FCO, van de Velde H, Vandenesch F, Naimi T, Enright MC,, Voyich JM, Otto M, Mathema B, et al, Yamasaki O, Kaneko J, Morizane S, e, 山本達男, 他   +12 more
core   +4 more sources

Skin Infections Due to Panton-Valentine Leukocidin-Producing S. Aureus.

Deutsches Ärzteblatt International, 2022
BACKGROUND Panton-Valentine leukocidin (PVL)-producing Staphylococcus aureus (PVL-SA) strains are frequently associated with large, recurring abscesses in otherwise healthy young individuals.
R. Leistner, L. Hanitsch, R. Krüger, A. Lindner, M. Stegemann, Dennis Nurjadi   +5 more
semanticscholar   +1 more source

TPST2-mediated receptor tyrosine sulfation enhances leukocidin cytotoxicity and S. aureus infection

Frontiers in Immunology, 2023
BackgroundAn essential fact underlying the severity of Staphylococcus aureus (S. aureus) infection is the bicomponent leukocidins released by the pathogen to target and lyse host phagocytes through specific binding cell membrane receptors.
Jie He, Xianggui Yang, Kai Yang, Honglin Xu, Cheng Chen, Junxiong Wang, Jun Zeng   +6 more
doaj   +1 more source

Vaccination With Detoxified Leukocidin AB Reduces Bacterial Load in a Staphylococcus aureus Minipig Deep Surgical Wound Infection Model

Journal of Infectious Diseases, 2021
Vaccines against Staphylococcus aureus have eluded researchers for >3 decades while the burden of staphylococcal diseases has increased. Early vaccine attempts mainly used rodents to characterize preclinical efficacy, and all subsequently failed in human
Jeffrey Fernandez, H. Sanders, Jessica Henn, Jolaine M Wilson, Danielle Malone, Alessandra Buoninfante, Matthew Willms, Rita Chan, Ashley L. DuMont, Craig McLahan, Kaitlyn Grubb, Anthony Romanello, G. V. D. van den Dobbelsteen, V. Torres, J. Poolman   +14 more
semanticscholar   +1 more source

Antigenic landscapes on Staphylococcus aureus pore-forming toxins reveal insights into specificity and cross-neutralization

mAbs, 2022
Staphylococcus aureus carries an exceptional repertoire of virulence factors that aid in immune evasion. Previous single-target approaches for S.
Shweta Kailasan, Ravi Kant, Madeleine Noonan-Shueh, Tulasikumari Kanipakala, Grant Liao, Sergey Shulenin, Daisy W. Leung, Richard A. Alm, Rajan P. Adhikari, Gaya K. Amarasinghe, Michael L. Gross, M. Javad Aman   +11 more
doaj   +1 more source

Endothelial ACKR1 is induced by neutrophil contact and down-regulated by secretion in extracellular vesicles

Frontiers in Immunology, 2023
Atypical chemokine receptor-1 (ACKR1), previously known as the Duffy antigen receptor for chemokines, is a widely conserved cell surface protein that is expressed on erythrocytes and the endothelium of post-capillary venules.
Xinying Guo, Xinying Guo, Negar Khosraviani, Negar Khosraviani, Sneha Raju, Joshya Singh, Nikki Zamani Farahani, Madlene Abramian, Victor J. Torres, Kathryn L. Howe, Jason E. Fish, Jason E. Fish, Andras Kapus, Andras Kapus, Warren L. Lee, Warren L. Lee, Warren L. Lee, Warren L. Lee   +17 more
doaj   +1 more source

The Host Adaptation of Staphylococcus aureus to Farmed Ruminants in New Zealand, With Special Reference to Clonal Complex 1. [PDF]

Environ Microbiol Rep
ABSTRACT Genetic features of host adaptation of S. aureus to ruminants have been extensively studied, but the extent to which this adaptation occurs in nature remains unknown. In New Zealand, clonal complex 1 (CC1) is among the most common lineages in humans and the dominant lineage in cattle, enabling between‐, and within‐CC genomic comparisons of ...
Nesaraj J, Grinberg A, Laven R, Chanyi R, Altermann E, Bandi C, Biggs PJ.   +6 more
europepmc   +2 more sources