Results 51 to 60 of about 84,306 (206)

The Association Between Allergic Rhinitis, Eosinophilic Inflammation, and Postoperative Recurrence in Nasal Polyps

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Although allergic rhinitis (AR) commonly co‐occurs with chronic rhinosinusitis with nasal polyps (CRSwNP), its impact on tissue endotypes and prognosis remains unclear. This study examines the impact of AR on CRSwNP, focusing on its links to tissue eosinophilic inflammation and postoperative recurrence risk.
Wei Zhong, Shaobing Xie, Haijun He, Hua Zhang, Weihong Jiang, Can Liao, Zhihai Xie   +6 more
wiley   +1 more source

Cooperation between interleukin-5 and the chemokine eotaxin to induce eosinophil accumulation in vivo. [PDF]

, 1995
Experiments were designed to study the effect of systemically administered IL-5 on local eosinophil accumulation induced by the intradermal injection of the chemokine eotaxin in the guinea pig.
Collins, PD, Griffiths-Johnson, DA, Jose, PJ, Marleau, S, Williams, TJ   +4 more
core   +2 more sources

In Vivo Effect of a Synthetic Amniotic Fluid on Fetal Lung and Gastrointestinal Tract: A Pre‐Clinical Rodent Model

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Amnioinfusions in anhydramnios aim to promote fetal lung development, but currently used fluids (Normal Saline [NS], Lactated Ringer's [LR]) fail to mimic the intrauterine environment and increase reactive oxygen species (ROS). We developed a synthetic amniotic fluid (Amnio‐well, AW) designed to reduce intrauterine ROS.
Braxton Forde, Stephanie Finoti, Marc Oria, Jose L. Peiro   +3 more
wiley   +1 more source

Two Pfam protein families characterized by a crystal structure of protein lpg2210 from Legionella pneumophila. [PDF]

, 2013
BackgroundEvery genome contains a large number of uncharacterized proteins that may encode entirely novel biological systems. Many of these uncharacterized proteins fall into related sequence families. By applying sequence and structural analysis we hope
Aravind, L, Axelrod, Herbert L, Bateman, Alex, Chang, Yuanyuan, Coggill, Penelope, Das, Debanu, Eberhardt, Ruth Y, Finn, Robert D, Godzik, Adam, Jaroszewski, Lukasz, Murzin, Alexey G, Xu, Qingping   +11 more
core   +2 more sources

Evidence‐based guideline for clinical practice in the diagnosis, treatment, management, and prevention of recurrent wheezing in infants and toddlers in China

Pediatric Investigation, EarlyView.
ABSTRACT Wheezing is a common respiratory symptom in infants and toddlers, and recurrent wheezing is a significant respiratory disorder affecting this age group. Given the multifactorial etiology of recurrent wheezing, clinical practice lacks standardized diagnostic and therapeutic protocols. Recent years have witnessed substantial progress in clinical
Committee of Pediatrics, China Medical Education Association, Cooperative Group of Asthma, the Subspecialty Group of Respiratory, the Society of Pediatrics, Chinese Medical Association, Pediatric Respiratory Work Committee, Society of Pulmonologists, Chinese Medical Doctor Association, Committee of Pediatrics, Chinese Research Hospital Association, Pediatric Professional Committee of the Chinese Non‐public Medical Institutions Association, Professional Committee of Children's Health and Pharmaceutical Research, China Association of Traditional Chinese Medicine, Children's Safe Medication Branch of China News of Drug Information Association, Pediatric Expert Committee of China Primary Health Care Foundation, China International Medical Foundation   +16 more
wiley   +1 more source

Phytochemical‐Based Strategies for Lung Cancer: Clinical Insights Into Pleiotropic Molecular Signaling and Therapeutic Roles

Phytotherapy Research, EarlyView.
Lung cancer (LC) remains the leading cause of global cancer‐related death. Phytochemicals from medicinal plants are increasingly being considered as potential LC treatment agents due to their multi‐targeted action, safety, and accessibility. These have anticancer properties by regulating key molecular signaling pathways.
Md. Rezaul Islam, Abdur Rauf, Happy Akter, Md. Ibrahim Khalil Al‐Imran, Md. Naeem Hossain Fakir, Gazi Kaifeara Thufa, Umme Habiba, Karjin Nahar Riya, Md. Mahfuzur Rahman, Md Sadique Hussain, Hanan A. Ogaly, Abdullah S. M. Aljohani, Waleed Al Abdulmonem, Dorota Formanowicz, Marcello Iriti   +14 more
wiley   +1 more source

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Leukotriene antagonists as first-line or add-on asthma controller therapy [PDF]

, 2011
Most randomized trials of treatment for asthma study highly selected patients under idealized conditions. METHODS: We conducted two parallel, multicenter, pragmatic trials to evaluate the real-world effectiveness of a leukotriene-receptor antagonist ...
Annie Blyth, Daryl Freeman, David Price, Ducharme FM, Edward C.F. Wilson, Elizabeth F. Juniper, Elizabeth V. Hillyer, Erika J. Sims, H. Miranda Mugford, Ian Harvey, Jamie Murdoch, Jon G. Ayres, Juniper EF, Lee Shepstone, Linda Kemp, Malmstrom K, O'Byrne PM, Richard F.T. Gilbert, Santanello NC, Stanley D. Musgrave, Stephanie Wolfe, Temple R, Thomas M   +22 more
core   +1 more source

Association Between Mediterranean Diet and the Incidence of Adult‐Onset Asthma in the SUN Project: A Spanish Prospective Cohort Study

Respirology, EarlyView.
In a long‐term prospective study of Spanish university students and graduates, higher adherence to the Mediterranean diet was associated with a lower risk of adult‐onset asthma. ABSTRACT Introduction Dietary factors have been suggested as drivers of asthma in children and adults. However, evidence is inconclusive.
Javier Errasti Viader, Carmen de la Fuente‐Arrillaga, Arantza Campo Ezquibela, Carmen Sayon‐Orea, Miguel Ángel Martínez‐González, Maira Bes‐Rastrollo   +5 more
wiley   +1 more source

Supra and subgingival application of antiseptics or antibiotics during periodontal therapy

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero, Jorge Serrano, Nicole Birgit Arweiler, Thorsten Mathias Auschill, Ali Gürkan, Gülnur Emingil   +5 more
wiley   +1 more source