Results 71 to 80 of about 123,231 (223)
Efficacy of leukotriene receptor antagonists and synthesis inhibitors in asthma
, 2009 Cysteinyl leukotrienes are important mediators of asthmatic responses. They are the most potent bronchoconstrictors known; their release is triggered by exposure to inhaled allergens after exercise and after aspirin ingestion by subjects with aspirin ...
O'Byrne, Paul M. +5 more
core +1 more source
Allergy, EarlyView.ABSTRACT Background To achieve adequate symptom control, patients with allergic rhinitis (AR) often need to increase their medication dose or add other treatments (co‐medication). We aimed to perform a systematic review to compare the efficacy and safety of AR medications for increased dose versus co‐medication.
Bernardo Sousa‐Pinto +44 more
wiley +1 more source
Leukotriene Synthesis Is Critical for Medulloblastoma Progression.
, 2019 Purpose: Here, we examined the role of leukotrienes, well-known inflammatory mediators, in the tumorigenesis of hedgehog pathway-associated medulloblastoma, and tested the efficacies of antagonists of leukotriene biosynthesis in medulloblastoma treatment.
Lee, Eric H +13 more
core +1 more source
PHARMACOLOGICAL APPROACH IN EXERCISE-INDUCED ASTHMA [PDF]
Sport Mont, 2012 Exercise-induced asthma is a transient airflow obstruction, which occurs after the strenuous exercise. It is a complex pathophysiological phenomenon, present in all levels of exercise, from children to professional athletes, so the therapy is specific ...
Biljana Vitošević +2 more
doaj
The problem of preschool wheeze: new developments, new questions
Acta Medica Lituanica, 2010 Preschool wheeze is a common and often difficult to treat symptom. It may rarely be the first presentation of a severe underlying condition. Preschool wheeze is clearly a syndrome, not a single entity, and thus ripe for phenotyping.
Andrew BUSH
doaj +1 more source
, 2022 S.6123-6134Sensitization of the heat-activated ion channel transient receptor potential vanilloid 1 (TRPV1) through lipids is a fundamental mechanism during inflammation-induced peripheral sensitization. Leukotriene B4 is a proinflammatory lipid mediator
Treutlein, E.M. +14 more
core +1 more source
Allergy, EarlyView.HDM‐pSLIT induced IgG, IgG1, and IgG4 specific to major HDM allergens in sensitized non‐allergic preschool children without increasing HDM‐sIgE. It blunted the development of new sensitizations and reduced HDM reactivity in skin and basophils. HDM‐pSLIT treated children displayed a blocking effect on HDM‐induced basophil activation.
Varsha Dwivedi +12 more
wiley +1 more source
MONTELUKAST AS ADD-ON THERAPY TO INHALED BECLOMETHASONE IN PERSISTENT BRONCHIAL ASTHMA
Pakistan Armed Forces Medical Journal, 2009 Objective: To evaluate the efficacy of Montelukast as add-on therapy in moderate persistent asthma with inadequate control on high dose inhaled beclomethasone. Study Design: A quasi experimental study.
Muhammad Babar Khan Khan +4 more
doaj +2 more sources
ROLE OF ANTILEUKOTRIENE DRUGS IN ACHIEVEMENT OF BRONCHIAL ASTHMA CONTROL
Медицинский совет, 2017 Bronchial asthma (BA) is a common chronic disease heterogeneous in nature and variable in its course. Heterogeneity in asthma is manifested in relation to the age of the onset, triggers, pattern of inflammation, severity of clinical manifestations and ...
N. M. Nenasheva
doaj +1 more source
Surgical Management of Non‐Allergic Rhinitis—An EAACI Task Force Position Paper
Allergy, EarlyView.ABSTRACT Non‐allergic rhinitis is a frequent yet underdiagnosed cause of chronic nasal symptoms, including nasal congestion, rhinorrhoea, and upper airway hyperreactivity. Its pathophysiology involves neurogenic dysregulation, leading to excessive mucus production and vasodilation.
Marie Lundberg +18 more
wiley +1 more source