Results 71 to 80 of about 13,142 (278)

ROLE OF ANTILEUKOTRIENE DRUGS IN ACHIEVEMENT OF BRONCHIAL ASTHMA CONTROL

Медицинский совет, 2017
Bronchial asthma (BA) is a common chronic disease heterogeneous in nature and variable in its course. Heterogeneity in asthma is manifested in relation to the age of the onset, triggers, pattern of inflammation, severity of clinical manifestations and ...
N. M. Nenasheva
doaj   +1 more source

Treatment Dose Increase Versus Co‐Medication in Allergic Rhinitis: Systematic Review With Dose–Response Network Meta‐Analysis

Allergy, EarlyView.
ABSTRACT Background To achieve adequate symptom control, patients with allergic rhinitis (AR) often need to increase their medication dose or add other treatments (co‐medication). We aimed to perform a systematic review to compare the efficacy and safety of AR medications for increased dose versus co‐medication.
Bernardo Sousa‐Pinto, Rafael José Vieira, Sara Gil‐Mata, Ana Margarida Pereira, Vítor Henrique Duarte, Antonio Bognanni, Manuel Marques‐Cruz, Paweł Jemioło, Mattia Giovannini, Danilo di Bona, Arnav Agarwal, Mark S. Dykewicz, Mohamed H. Shamji, Maria Jose Torres, Torsten Zuberbier, Ludger Klimek, Alexandro W. L. Chu, Holger J. Schünemann, Guido Schwarzer, João A. Fonseca, Jean Bousquet, on behalf of the ARIA 2024–2025 systematic reviews group, Ana Teixeira‐Ferreira, André Ferreira, António Cardoso‐Fernandes, Despo Ierodiakonou, Diana Portela, Ewa Borowiack, Ewelina Sadowska, Henrique Ferreira‐Cardoso, Hugo Viegas, Izabel Pera Calvi, João Castro‐Teles, José Laerte Boechat, Juliana Pereira‐Macedo, Maria Inês Torres, Marta Soares Pereira, Miguel Campos‐Lopes, Nuno Lourenço‐Silva, Pau Riera‐Serra, Paula Perestrelo, Raquel Albuquerque‐Costa, Renato Ferreira‐da‐Silva, Rita A. Silva Ribeiro, Tuuli Thomander   +44 more
wiley   +1 more source

Pharmacogenetics of anti-inflammatory therapy in asthma: Corticosteroids and leukotriene antagonists

, 2010
Asthma is a chronic airway disease with a relatively high prevalence. Although the etiology of asthma is still not fully clear, there are effective treatments available.
van der Ent, Cornelis K., Raaijmakers, Jan A.M., Vijverberg, Susanne J.H., Koster, Ellen S., Maitland-van der Zee, Anke Hilse   +4 more
core   +1 more source

Preventive Application of House Dust Mite‐Sublingual Immunotherapy Induces Blocking Antibodies in Sensitized Preschool Children

Allergy, EarlyView.
HDM‐pSLIT induced IgG, IgG1, and IgG4 specific to major HDM allergens in sensitized non‐allergic preschool children without increasing HDM‐sIgE. It blunted the development of new sensitizations and reduced HDM reactivity in skin and basophils. HDM‐pSLIT treated children displayed a blocking effect on HDM‐induced basophil activation.
Varsha Dwivedi, Klara Schmidthaler, Hilal Demir, Justyna Sieber, René Gaupmann, Livia Mia Gona‐Höpler, Christina Bannert, Saskia Gruber, Eleonora Dehlink, Thomas Eiwegger, Alexandra Graf, Barbara Bohle, Zsolt Szépfalusi   +12 more
wiley   +1 more source

Inhibition of Common Cold-Induced Aggravation of Childhood Asthma by Leukotriene Receptor Antagonists

Allergology International, 2012
Background: : Virus infection is an important risk factor for aggravation of childhood asthma. The objective of this study was to examine the effect of drugs on aggravation of asthma induced by a common cold.
Shigemi Yoshihara, Hironobu Fukuda, Toshio Abe, Mitsuhiro Nishida, Yumi Yamada, Noriko Kanno, Osamu Arisaka   +6 more
doaj   +1 more source

Asthma pharmacotherapy: an update on leukotriene treatments

, 2019
INTRODUCTION: Asthma is a chronic inflammatory disease of the airways with a large heterogeneity of clinical phenotypes. There has been increasing interest regarding the role of cysteinyl leukotriene (LT) and leukotriene receptor antagonists (LTRA) in ...
Cao, TBT, Park, HS, Lee, SH, Trinh, HKT
core   +1 more source

Diet–Microbiome–Immune Interactions at the Gut Mucosa in Food Allergy: Mechanisms, Gaps, and Therapeutic Implications

Allergy, EarlyView.
ABSTRACT Mucosal surfaces are sites of highly dynamic interactions among epithelial and immune cells, environmental exposures, particularly dietary inputs, and the diverse microbial communities and their metabolites. These elements continually influence each other to maintain homeostasis and ensure appropriate immune discrimination between pathogens ...
Clara Delaroque, Liam O'Mahony, Inge Kortekaas Krohn, Charlotte G. Mortz, Markus Ollert, Mahesh S. Desai   +5 more
wiley   +1 more source

Leukotriene signaling in atherosclerosis and ischemia.

, 2009
International audienceINTRODUCTION: The inflammatory process of atherosclerosis is associated with several pathophysiological reactions within the vascular wall.
Bäck, Magnus, Back, M
core   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

Leukotriene-receptor antagonists versus placebo in the treatment of asthma in adults and adolescents a systematic review and meta-analysis

, 2015
Background: Leukotriene-receptor antagonists (LTRAs) are recommended as an alternative treatment in patients with mild asthma, but their effect compared with placebo is unclear.
Miligkos M., Bannuru R.R., Alkofide H., Kher S.R., Schmid C.H., Balk E.M.
core   +1 more source