Results 121 to 130 of about 15,891 (187)

Activation of leukotriene B₄ receptor 1 is a prerequisite for complement receptor 3-mediated antifungal responses of neutrophils. [PDF]

Cell Mol Immunol
Xin Y, Xiong S, Zhou L, Lin X.
europepmc   +1 more source

Dual inhibition of complement factor 5 and leukotriene B4 synergistically suppresses murine pemphigoid disease. [PDF]

JCI Insight, 2019
Sezin T, Murthy S, Attah C, Seutter M, Holtsche MM, Hammers CM, Schmidt E, Meshrkey F, Mousavi S, Zillikens D, Nunn MA, Sadik CD.   +11 more
europepmc   +1 more source

Correction: Role of the high-affinity leukotriene B4 receptor signaling in fibrosis after unilateral ureteral obstruction in mice. [PDF]

PLoS One, 2019
Kamata M, Amano H, Ito Y, Fujita T, Otaka F, Hosono K, Kamata K, Takeuchi Y, Yokomizo T, Shimizu T, Majima M.   +10 more
europepmc   +1 more source

Leukotriene B4 promotes neovascularization and macrophage recruitment in murine wet-type AMD models. [PDF]

JCI Insight, 2018
Sasaki F, Koga T, Ohba M, Saeki K, Okuno T, Ishikawa K, Nakama T, Nakao S, Yoshida S, Ishibashi T, Ahmadieh H, Kanavi MR, Hafezi-Moghadam A, Penninger JM, Sonoda KH, Yokomizo T.   +15 more
europepmc   +1 more source

Leukotrien B4 in uveitis.

Ensho, 1991
openaire   +2 more sources

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Leukotriene B4

International Journal of Biochemistry and Cell Biology, 1998
Leukotriene B4 is a pro-inflammatory mediator synthesised in myeloid cells from arachidonic acid. Synthesis is catalysed by 5-lipoxygenase and leukotriene A4 hydrolase and is increased by inflammatory mediators including endotoxin, complement fragments, tumor necrosis factor and interleukins.
Robert Stockley, R A Stockley
exaly   +3 more sources

Biosynthesis of leukotriene B4

Seminars in Immunology, 2017
Leukotriene B4 (LTB4) is a lipid mediator derived from arachidonic acid (AA) by the sequential action of 5-lipoxygenase (5-LOX), 5-lipoxygenase-activating protein (FLAP) and LTA4 hydrolase (LTA4H). It was initially recognized for its involvement in the recruitment of neutrophils and is one of the most potent chemotactic agents known to date.
Min, Wan, Xiao, Tang, Alena, Stsiapanava, Jesper Z, Haeggström   +3 more
openaire   +2 more sources

A radioimmunoassay for leukotriene B4

Prostaglandins, 1982
A radioimmunoassay for leukotriene B4 has been developed. The assay is sensitive; 5 pg LTB4 caused significant inhibition of binding of [3H]-LTB4 and 50% displacement occurred with 30 pg. The specificity of the assay has been critically examined; prostaglandins, thromboxane B2 and arachidonic acid do not exhibit detectable cross-reactions (less than 0 ...
J A, Salmon, P M, Simmons, R M, Palmer
openaire   +2 more sources

Leukotriene B4 in Hemodialysis

Artificial Organs, 1990
Abstract: Leukotrienes are eicosanoids arising from arachidonic acid via 5 lipooxygenase, an enzyme essentially present in leukocyte cells. Leukotriene B4 might be an indicator of neutropolymorphonuclear leukocyte activation when there is contact with artificial membranes.
A, Tridon, E, Albuisson, P, Deteix, A, Marquès Verdier, G, Gaillard, G, Bétail, J C, Baguet   +6 more
openaire   +2 more sources

Leukotriene B4 receptors

Prostaglandins & Other Lipid Mediators, 2002
Leukotriene B4 (LTB4) is a potent chemotactic agent and activating factor for granulocytes. Two cell surface receptors for LTB4 (BLT1 and BLT2) have been isolated in the last few years. These receptors are G-protein-coupled receptors (GPCR), and they have 45% amino acid identity. BLT1 and BLT2 are high- and low- affinity receptors, respectively.
Akiko, Toda, Takehiko, Yokomizo, Takao, Shimizu   +2 more
openaire   +2 more sources