Results 61 to 70 of about 29,166 (227)

Redox processes are major regulators of leukotriene synthesis in neutrophils exposed to bacteria Salmonella typhimurium; the way to manipulate neutrophil swarming

Frontiers in Immunology
Neutrophils play a primary role in protecting our body from pathogens. When confronted with invading bacteria, neutrophils begin to produce leukotriene B4, a potent chemoattractant that, in cooperation with the primary bacterial chemoattractant fMLP ...
Ekaterina A. Golenkina, Galina M. Viryasova, Svetlana I. Galkina, Natalia D. Kondratenko, Tatjana V. Gaponova, Yulia M. Romanova, Konstantin G. Lyamzaev, Konstantin G. Lyamzaev, Boris V. Chernyak, Galina F. Sud’ina   +9 more
doaj   +1 more source

Inhibition of release of inflammatory in primary and cultured cells by a Chinese herbal medicine formula for allergic rhinitis [PDF]

, 2007
BACKGROUND - We demonstrated that a Chinese herbal formula, which we refer to as RCM-101, developed from a traditional Chinese medicine formula, reduced nasal and non-nasal symptoms of seasonal allergic rhinitis (SAR).
Lenon, G, Li, C, Mcphee, S, Story, D, Thien, F, Xue, C   +5 more
core  

Addition to inhaled corticosteroids of long-acting beta2-agonists versus anti-leukotrienes for chronic asthma [PDF]

, 2011
Asthma patients who continue to experience symptoms despite being on regular inhaled corticosteroids (ICS) represent a management challenge. Long-acting beta2-agonists (LABA) or anti-leukotrienes (LTRA) are two treatment options that could be considered ...
Adams, Adinoff, Altman, Anonymous, Anonymous, Anonymous, Baraniuk, Barnes, Bateman, Bateman, Becker, Bergmann, Bjermer, Bjermer, Bjermer, Bleecker, Borker, Boulet, Bousquet, Brabson, Buchvald, Buchvald, Buhl, Busse, Caffey, Calhoun, Calhoun, Cash, Cates, Ceylan, Chopra, Chuchalin, Covar, Currie, Currie, Currie, Davies, Davis, Deeks, Dekhuijzen, Delaronde, Dempsey, Deykin, Dicpinigaitis, Donohue, Dorinsky, Dorinsky, Dorinsky, Dorinsky, Ducharme, Ducharme, Ducharme, Ducharme, Dunn, Edelman, Edin, Egger, Eliraz, Eliraz, Ernst, Everden, Fish, Fish, Gabrijelcic, Georgitis, Giannini, Gold, Gold, Green, Green, Green, Grosclaude, Grzelewska-Rzymowska, Gupta, Havlucu, Hendeles, Higgins, Higgins, Horwitz, Houghton, Ilowite, Inoue, Jarvis, Jarvis, Jenkins, Johnson, Jonsson, Kalberg, Kalberg, Kanniess, Kanniess, Karaman, Kardos, Keith, Kemp, Keonig, Kerwin, Knobil, Knorr, Koenig, Kohrogi, Krawiec, Larsen, Laviolette, Lazarus, Lee, Lee, Lee, Lee, Leflein, Leibman, Leibman, Lemanske, Lipworth, Lipworth, Liu, Lotvall, Lougheed, Maspero, Maspero, Maspero, McCarthy, McCarthy, Meltzer, Miraglia del Giudice, Mitchell, Molitor, Naedele-Risha, Nathan, Nathan, Nathan, Nathan, Nathan, Nelson, Nelson, Nelson, Nelson, Nelson, Ni Chroinin, Ni Chroinin, Nsouli, O'Connor, O'Sullivan, Ohbayashi, Ohbayashi, Ollendorf, Oppenheimer, Orgega-Cisneros, Paterson, Pavord, Pearlman, Perera, Perez, Peroni, Peroni, Petermann, Peters, Pieters, Pieters, Plaza, Polos, Powell, Price, Ram, Reddel, Rees, Riccioni, Rickard, Rickard, Ringdal, Ringdal, Rosenhall, Salpeter, Serrier, Sheth, Sims, Sims, Sims, Smith, Sorkness, Stanford, Stelmach, Stelmach, Stelmach, Stelmach, Stelmach, Stelmach, Stempel, Stempel, Stevenson, Storms, Storms, Terzano, Thien, Tolley, Vaquerizo, Volovitz, Walters, Warner, Wasserman, Wenzel, Wilson, Wilson, Wilson, Wytrychowski, Yurdakul, Zarkovic, Zimmerman   +207 more
core   +1 more source

Bruton tyrosine kinase (Btk) in neutrophils is indispensable for initiating and maintaining skin inflammation in a model of pemphigoid diseases

British Journal of Pharmacology, EarlyView.
Background and Purpose Bruton tyrosine kinase (Btk) is essential for B cell function. Its role in myeloid cells is less understood. Greater insights into Btk significance in myeloid cells are needed to evaluate its potential as a therapeutic target during the effector phase of antibody‐induced autoimmune diseases, where inhibiting autoantibody ...
Henning Olbrich, Paul Schilf, Sripriya Murthy, Sina Gonther, Mareike Neumann, Christoph M. Hammers, Jasper N. Pruessmann, Christian D. Sadik   +7 more
wiley   +1 more source

The Role of Leukotriene B4 in Allergic Diseases

Allergology International, 2008
Leukotriene B4 (LTB4) is a lipid mediator with potent chemoattractant properties and that is rapidly generated from activated innate immune cells such as neutrophils, macrophages, and mast cells.
Hiroshi Ohnishi, Nobuaki Miyahara, Erwin W Gelfand   +2 more
doaj   +1 more source

Inhaled corticosteroid effects both eosinophilic and non-eosinophilic inflammation in asthmatic patients

Mediators of Inflammation, 2004
AIM: To determine induced sputum cell counts and interleukin-8 (IL-8), tumor necrosis factor alpha (TNF-α) and leukotriene B4 (LTB4) levels as markers of neutrophilic inflammation in moderate persistent asthma, and to evaluate the response to inhaled ...
Ilknur Basyigit, Fusun Yildiz, Sevgiye Kacar Ozkara, Hasim Boyaci, Ahmet Ilgazli   +4 more
doaj   +1 more source

Augmentation of 5-lipoxygenase activity and expression during dengue serotype-2 infection [PDF]

, 2013
published_or_final_versio
Chow, AY, Halliwell, B, Lam, KMS, Lee, CYJ, Lim, ECH, Loke, WM, Ooi, EE, Quek, AML, Seet, RCS   +8 more
core   +1 more source

Cellular Signalling Networks in High Altitude Pulmonary Hypertension: From Canonical Pathways to Emerging Targets

Cell Proliferation, EarlyView.
This review elucidates the intricate cellular signalling networks involved in high‐altitude pulmonary hypertension (HAPH), integrating canonical pathways like HIF, MAPK and BMP with emerging targets such as Wnt/β‐catenin, Notch, Hippo‐YAP and IL‐6. It highlights potential therapeutic strategies targeting these pathways to mitigate vascular remodelling ...
Sheng Ding, Ju Chen, Zhaoyang Li, Yang Yu, Weijie Wang, Yan Liao, Jin Yang, Dianxiang Lu, Yujiang Fan   +8 more
wiley   +1 more source

Stimulus specificity of the generation of leukotrienes by dog mastocytoma cells. [PDF]

, 1983
Isolated dog mastocytoma cells sensitized with dog anti-ragweed IgE and challenged with ragweed antigen or incubated with ionophore A23187 or the carboxy-terminal dodecapeptide of platelet factor 4, PF4(59-70), release histamine and concurrently generate
Goetzl, EJ, Gold, WM, Phillips, MJ
core  

長期間喫煙による気管支唱息,肺気腫の病態的変化 [PDF]

, 2004
The influence of long-term cigarette smoking on the pathophysiology of chronic respiratory diseases with obstructive ventilatory dysfunction was discussed in patients with asthma and pulmonary emphysema (PE). 1.
Ashida, Kozo, Fujii, Makoto, Hamada, Masanori, Hosaki, Yasuhiro, Iwagaki, Naofumi, Mitsunobu, Fumihiro, Takata, Shingo, Tanizaki, Yoshiro   +7 more
core   +1 more source