Results 81 to 90 of about 29,166 (227)

Efficacy of ω-3 supplementation in patients with psoriasis:a meta-analysis of randomized controlled trials [PDF]

, 2019
Several studies have been conducted with the aim of investigating the effect of Omega(Ï )-3 on different psoriasis indices including Psoriasis Area and Severity Index (PASI) score, erythema, scaling, itching, area involved, and infiltration. Nevertheless,
Clark, Cain, Jafarnejad, Sadegh, Nahavandi, Mina, Taghizadeh, Mohsen   +3 more
core   +2 more sources

Pharmacokinetics and Anti‐Inflammatory Effects of Intramuscular Betamethasone in Exercised Thoroughbred Horses

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The pharmacokinetics and pharmacodynamics of betamethasone following intra‐articular administration to horses have been described; however, studies characterizing intramuscular administration are lacking. Twenty‐four horses received an intramuscular dose of 12 mg betamethasone sodium phosphate/betamethasone acetate.
Juliana Sullivan, Jeff Blea, Daniel S. McKemie, Philip H. Kass, Heather K. Knych   +4 more
wiley   +1 more source

Psoriasis—An Immunological Disease [PDF]

, 1996
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/111129/1/jde02714 ...
Alroy, Baadsgaard, Bach, Bata-Csorgo, Berg, Cronstein, Ellis, Enk, Gandangi, Griffiths, Griffiths, Halprin, Hammarstrom, Judge, Menssen, Morganroth, Mueller, Nesde, Rivas, Robinson, Scheinman, Schlaak, Uyemura, Valdimarsson, Voorhees, Voorhees, Weinstein   +26 more
core   +1 more source

HTLV-1-induced leukotriene B4 secretion by T cells promotes T cell recruitment and virus propagation

Nature Communications, 2017
HTLV-1 predominantly spreads through direct cell-cell contacts, but mechanisms of target cell recruitment are unclear. Here, the authors show that HTLV-1 infected T-cells secrete leukotriene B4, which recruits T-cells, facilitates HTLV-1 transmissionin ...
Florent Percher, Céline Curis, Eléonore Pérès, Maria Artesi, Nicolas Rosewick, Patricia Jeannin, Antoine Gessain, Olivier Gout, Renaud Mahieux, Pierre-Emmanuel Ceccaldi, Anne Van den Broeke, Madeleine Duc Dodon, Philippe V. Afonso   +12 more
doaj   +1 more source

Inhibition of LTA4H by bestatin in human and mouse colorectal cancerResearch in context

EBioMedicine, 2019
Background: Our preclinical data showed that the leukotriene A4 hydrolase (LTA4H) pathway plays a role in colorectal cancer (CRC). High expression of LTA4H and leukotriene B4 receptor type 1 (BLT1) were also associated with CRC survival probability ...
Simin Zhao, Ke Yao, Dan Li, Kangdong Liu, Guoguo Jin, Mingyang Yan, Qiong Wu, Hanyong Chen, Seung Ho Shin, Ruihua Bai, Gangcheng Wang, Ann M. Bode, Ziming Dong, Zhiping Guo, Zigang Dong   +14 more
doaj   +1 more source

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

Let-7 microRNA-dependent control of leukotriene signaling regulates the transition of hematopoietic niche in mice

Nature Communications, 2017
Hematopoietic stem and progenitor cells are generated first from the vascular endothelium of the dorsal aorta and then the fetal liver but what regulates this switch is unknown.
Xuan Jiang, John S. Hawkins, Jerry Lee, Carlos O. Lizama, Frank L. Bos, Joan P. Zape, Prajakta Ghatpande, Yongbo Peng, Justin Louie, Giorgio Lagna, Ann C. Zovein, Akiko Hata   +11 more
doaj   +1 more source

Glucuronidation of arachidonic and linoleic acid metabolites by human UDP-glucuronosyltransferases

Journal of Lipid Research, 2003
Arachidonic acids (AA) and linoleic acids (LAs) are metabolized, in several tissues, to hydroxylated metabolites that are important mediators of many physiological and pathophysiological processes.
David Turgeon, Sarah Chouinard, Patrick Bélanger, Serge Picard, Jean-François Labbé, Pierre Borgeat, Alain Bélanger   +6 more
doaj   +1 more source

Mechanisms of Aristolochic Acid Resistance in Specialist Butterflies and Evolutionary Insights for Potential Protective Pathways

Advanced Science, Volume 13, Issue 19, 2 April 2026.
The study provides an extreme example of insect adaptation to highly toxic defenses of host plants, and investigates the complex strategies to resist carcinogenic aristolochic acids, including physical isolation, metabolic detoxification, and DNA repair.
Yang Luan, Yubo Zhang, Jingjing Li, Jianqing Zhu, Yuyang Lei, Yushi Hu, Zhenqiang Xin, Tianpei Xie, Jiang Zheng, Yuanyuan Lin, Jingjing Shen, Yiyi Cao, Xinyue You, Jing Xi, Jiaying Wu, Weiying Liu, Xinyu Zhang, Yuanting Zheng, David J. Lohman, Leming Shi, Wei Zhang   +20 more
wiley   +1 more source

Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission. [PDF]

, 2017
Linoleic acid (LA; 18:2 n-6), the most abundant polyunsaturated fatty acid in the US diet, is a precursor to oxidized metabolites that have unknown roles in the brain.
Bazinet, Richard P, Hammock, Bruce D, Hennebelle, Marie, Kitson, Alex P, Lee, Kin Sing Stephen, Metherel, Adam H, Otoki, Yurika, Richardson, Christine E, Taha, Ameer Y, Yang, Jun, Zhang, Liang, Zhang, Zhichao   +11 more
core   +1 more source