Results 101 to 110 of about 354,007 (274)

Is Leukotriene Receptor Antagonist the Direct Cause of Churg-Strauss Syndrome in Asthmatic Patients? [PDF]

Cureus, 2022
Paul S, Yakkali S, Teresa Selvin S, Thomas S, Bikeyeva V, Abdullah A, Radivojevic A, Abu Jad AA, Ravanavena A, Ravindra C, Igweonu-Nwakile EO, Ali S, Hamid P.   +12 more
europepmc   +1 more source

Neuronal and ion channel mechanisms of noxious heat sensing in mammals: A puzzle of sensory physiology and pharmacology

British Journal of Pharmacology, EarlyView.
Transient receptor potential vanilloid 1 (TRPV1) was the first noxious heat‐sensitive channel discovered. In rodents, its role is robust in the heat response of the cell body of polymodal nociceptors, but surprisingly small in that of the peripheral terminals in the skin.
Gábor Pethő, Peter W. Reeh
wiley   +1 more source

Clinical and functional characteristics of OSA in children with comorbid asthma treated by leukotriene receptor antagonist: A descriptive study. [PDF]

Front Neurol, 2022
Duong-Quy S, Nguyen-Hoang Y, Nguyen-Ngoc-Quynh L, Nguyen-Thi-Phuong M, Nguyen-Thi-Bich H, Le-Thi-Minh H, Nguyen-Thi-Dieu T.   +6 more
europepmc   +1 more source

Potentiation of Indomethacin-Induced Anti-Inflammatory Response by Montelukast in Formalin-Induced Inflammation in Rats

Acta Medica Iranica, 2013
The leukotrienes and prostaglandins are biologically active metabolites derived from arachidonic acid. The leukotrienes have a role in inflammatory diseases such as allergic rhinitis, inflammatory bowel disease and asthma.
Ali Asghar Hemmati, Behnam Ghorbanzadeh, Mohammad Amin Behmanesh   +2 more
doaj  

A Real‐World Controlled Multicentre Study Evaluating the Association Between Benralizumab Therapy and Major Outcomes in Severe Asthma

Clinical &Experimental Allergy, EarlyView.
Among patients with severe eosinophilic asthma, benralizumab was associated with greater improvements in asthma outcomes—such as improved asthma control, quality of life and remission rates—compared to biologic‐naïve patients. ABSTRACT Background Real‐world data on benralizumab in patients with severe eosinophilic asthma–while controlling for ...
Dennis Thomas, Vanessa M. McDonald, Gijo Thomas, Joy Lee, Li Ping Chung, Matthew Peters, Shakti D. Shukla, Yuto Hamada, Erin S. Harvey, Michael Fricker, Hayley See, Rejoy Sabin Thomas, Claude S. Farah, Andrew Gillman, Constance H. Katelaris, Gregory P. Katsoulotos, David Langton, Peter G. Middleton, Paul Reynolds, Janet Rimmer, Francis Thien, Stephen Vincent, John W. Upham, Peter G. Gibson   +23 more
wiley   +1 more source

Integrated Transcriptomic and Structural Biophysical Analysis of Cysteinyl Leukotriene Receptors in Chronic Rhinosinusitis with Nasal Polyps

Biophysica
Background: Leukotriene receptor antagonists used in airway disease predominantly inhibit CysLT1R, whereas the relative disease-associated expression and structural context of CysLT1R and CysLT2R in chronic rhinosinusitis with nasal polyps (CRSwNP ...
Ece Celik
doaj   +1 more source

Montelukast: The New Therapeutic Option for the Treatment of Epilepsy

Journal of Experimental Pharmacology, 2021
Bekalu Amare Tesfaye, Haftom Gebregergs Hailu, Kaleab Alemayehu Zewdie, Muluken Altaye Ayza, Derbew Fikadu Berhe Department of Pharmacology and Toxicology, School of Pharmacy, Mekelle University, Mekelle, EthiopiaCorrespondence: Haftom Gebregergs Hailu ...
Tesfaye BA, Hailu HG, Zewdie KA, Ayza MA, Berhe DF   +4 more
doaj  

Leukotriene Receptor Antagonist Use and Dementia Risk in Patients With Asthma: A Retrospective Cohort Study. [PDF]

In Vivo, 2021
Ishikura Y, Maeda-Minami A, Hosokawa M, Onoda A, Kawano Y, Ihara T, Sugamata M, Takeda K, Mano Y.   +8 more
europepmc   +1 more source

Can Leukotriene Receptor Antagonist Therapy Improve the Control of Patients with Severe Asthma on Biological Therapy and Coexisting Bronchiectasis? A Pilot Study. [PDF]

J Clin Med, 2022
Quaranta VN, Dragonieri S, Crimi N, Crimi C, Santus P, Menzella F, Pelaia C, Scioscia G, Caruso C, Bargagli E, Kostikas K, Kyriakopoulos C, Scichilone N, Carpagnano GE.   +13 more
europepmc   +1 more source

Olfactory Tuft Cells Are Critical to Basal Inflammation, Innate Immune Response to Viral Infection, and Modulation of Quiescent Stem Cell Activation, Proliferation and Differentiation

Cell Proliferation, EarlyView.
Olfactory tuft cells communicate with other mucosal cells in maintaining olfactory epithelial immunity and sensory function. Disruption of tuft cell signalling pathways causes a skewed immune response, leading to heightened inflammation and increased activation of the quiescent stem cells, which are further exacerbated by viral infection.
Sai‐Sai Zhang, Haiyan Wang, Yi‐Sen Yang, Yi‐Hong Li, Defu Yu, Yushi Yao, Ruhong Zhou, Liquan Huang   +7 more
wiley   +1 more source