FIRST 5-DAYS FOLLOW-UP AND CORRELATION STUDY BETWEEN URINARY CYSTEINYL LEUKO TRIENES AND EDEMA VALUES IN PRIMARY SPONTANEOUS SUPRATENTORIAL INTRACEREBRAL HEMO RRHAGE [PDF]
Sanamed, 2014 Background: After intracerebral hemorrhage cysteinyl leukotrienes (C4, D4, E4) are synthetisized in the contact brain parenchyma-extravasated blood and participate in producing of edema formation.
Dolnenec-Baneva Natalia +3 more
doaj +6 more sources
Leukotrienes vs. Montelukast—Activity, Metabolism, and Toxicity Hints for Repurposing
Pharmaceuticals, 2022 Increasing environmental distress is associated with a growing asthma incidence; no treatments are available but montelukast (MTK)—an antagonist of the cysteinyl leukotrienes receptor 1—is widely used in the management of symptoms among adults and ...
Cátia F. Marques +2 more
doaj +1 more source
Concentrations of Cysteinyl Leukotrienes in Various Biological Fluids of Children with Bronchial Asthma, Atopic Dermatitis and Food Protein Induced Enterocolitis [PDF]
, 2019 Clinical manifestation of food allergy is characterized by polymorphic cutaneous, respiratory and gastrointestinal syndromes. Leukotrienes occupy a key place in the pathogenesis of a wide range of inflammatory diseases, including bronchial asthma ...
Haiduchyk, H. (Halyna) +1 more
core +4 more sources
Leukotrienes in Tumor-Associated Inflammation
Frontiers in Pharmacology, 2020 Leukotrienes are biologically active eicosanoid lipid mediators that originate from oxidative metabolism of arachidonic acid. Biosynthesis of leukotrienes involves a set of soluble and membrane-bound enzymes that constitute a machinery complex primarily ...
Wen Tian +10 more
doaj +1 more source
Montelukast induces beneficial behavioral outcomes and reduces inflammation in male and female rats
Frontiers in Immunology, 2022 BackgroundAccumulative data links inflammation and immune dysregulation to the pathophysiology of mental disorders; little is known regarding leukotrienes’ (LTs) involvement in this process.
Ira S. Rostevanov +8 more
doaj +1 more source
Plants, 2023 Arnica montana is well known for its anti-inflammatory properties. While the anti-inflammatory activity of Arnica flowers (Arnicae flos) has been extensively studied, that of the whole plant (Arnicae planta tota) is less characterized.
Johann Röhrl +8 more
doaj +1 more source
Медицинская иммунология, 2022 Rhinitis is a socially significant and widespread disease. Often, various forms of rhinitis are combined, and thus cause severe clinical manifestations, insufficient effectiveness of drug treatment, as well as difficulties in differential diagnosis.
O. A. Kulikova +4 more
doaj +1 more source
Diurnal rhythm of plasma EPA and DHA in healthy adults [PDF]
, 2020 Knowledge of the diurnal variation in circulating omega-3 polyunsaturated fatty acids (n-3 PUFAs) may be an important consideration for the development of dosing protocols designed to optimise tissue delivery of these fatty acids.
Avery, Hannah +7 more
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Leukotrienes, leukotriene receptor antagonists, and rhinitis [PDF]
Allergy, 2000 A series of clinical studies have shown the ef®cacy of leukotriene (LT) receptor antagonists (LTRAs) in the treatment of bronchial asthma (1±6). LTRAs relieve bronchospasm, prevent exercise-induced asthma, and reduce bronchial hyperresponsiveness.
N, Mygind, R, Dahl, H, Bisgaard
openaire +2 more sources
Addition to inhaled corticosteroids of long-acting beta2-agonists versus anti-leukotrienes for chronic asthma [PDF]
, 2011 Asthma patients who continue to experience symptoms despite being on regular inhaled corticosteroids (ICS) represent a management challenge. Long-acting beta2-agonists (LABA) or anti-leukotrienes (LTRA) are two treatment options that could be considered ...
Adams +207 more
core +1 more source