Results 31 to 40 of about 28,631 (145)

A review of practical strategies for managing bronchial asthma in conventional medical systems

open access: yesIndian Journal of Allergy Asthma and Immunology
Bronchial asthma is a chronic airway condition affecting about 10%–12% of adults and 15% of children worldwide. Treatment guidelines vary by asthma nature and severity.
Khadija Abdul Hafiz   +2 more
doaj   +1 more source

Occupational asthma follow-up — Which markers are elevated in exhaled breath condensate and plasma?

open access: yesInternational Journal of Occupational Medicine and Environmental Health, 2014
Objectives: To search for optimal markers in the exhaled breath condensate (EBC), plasma and urine that would reflect the activity/ severity of occupational asthma (OA) after the withdrawal from the exposure to the allergen. Material and Methods: Markers
Daniela Pelclová   +10 more
doaj   +1 more source

NSAID-Exacerbated Respiratory Disease (NERD): From Pathogenesis to Improved Care

open access: yesFrontiers in Pharmacology, 2020
Nonsteroidal antiinflammatory drug (NSAID)-exacerbated respiratory disease (NERD) is characterized by moderate-to-severe asthma and a higher prevalence of chronic rhinosinusitis/nasal polyps, but is a highly heterogeneous disorder with various clinical ...
Seong-Dae Woo   +4 more
doaj   +1 more source

The features of bile acids exchange in rats under the influence of corvitin [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2017
Corvitin is a soluble form of quercetin (QUE) and its effects are based on the ability to inhibit the activity of 5-lipoxygenase and to block the formation of leukotrienes.
T. V. Vovkun   +6 more
doaj   +1 more source

Lipoxygenase pathways in Homo neanderthalensis: functional comparison with Homo sapiens isoforms

open access: yesJournal of Lipid Research, 2013
Lipoxygenases (LOX) have been implicated in biosynthesis of pro- and anti-inflammatory mediators, and a previous report suggested compromised leukotriene signaling in H. neanderthalensis.
Pavlos Chaitidis   +5 more
doaj   +1 more source

LEUKOTRIENES AND ANTILEUKOTRIENE DRUGS IN ALLERGIC RHINITIS

open access: yesПедиатрическая фармакология, 2009
Allergic rhinitis is an allergic inflammation of the nasal mucosa due to sensitization to some inhalation allergens. There are two phases of a systemic allergic reaction depending on interaction of different cell types a biochemical mediators — the early
M.A. Zharkikh   +2 more
doaj   +2 more sources

Eicosanoid Control Over Antigen Presenting Cells in Asthma

open access: yesFrontiers in Immunology, 2018
Asthma is a common lung disease affecting 300 million people worldwide. Allergic asthma is recognized as a prototypical Th2 disorder, orchestrated by an aberrant adaptive CD4+ T helper (Th2/Th17) cell immune response against airborne allergens, that ...
Nincy Debeuf   +4 more
doaj   +1 more source

A current review on animal models of anti-asthmatic drugs screening

open access: yesFrontiers in Pharmacology
Asthma is a chronic inflammatory respiratory condition characterised by airway constriction, smooth muscle spasm, and severe morbidity. It affects around 300 million people globally, with children being especially vulnerable. Despite its worldwide effect,
Shivam Singh   +5 more
doaj   +1 more source

Unmasking the role of mast cells in dengue

open access: yeseLife, 2013
Immune cells called mast cells can hinder rather than help the body's response to dengue virus, which suggests that mast cell products could be used as biomarkers to identify severe forms of the disease.
Panisadee Avirutnan   +1 more
doaj   +1 more source

Cysteinyl Leukotrienes in Eosinophil Biology: Functional Roles and Therapeutic Perspectives in Eosinophilic Disorders

open access: yesFrontiers in Medicine, 2017
Cysteinyl leukotrienes (cysLTs), LTC4, and its extracellular metabolites, LTD4 and LTE4, have varied and multiple roles in mediating eosinophilic disorders including host defense against parasitic helminthes and allergic inflammation, especially in the ...
Glaucia A. Thompson-Souza   +2 more
doaj   +1 more source

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