Results 31 to 40 of about 35,647 (293)
Studies of Pathophysiology in Endotoxin Shock : Significance of Leukotrienes [PDF]
, 1988 In recent years, it has been reported that leukotrienes （LTs） play an important role in endotoxin shock. In the present investigation the author measured leukotrienes in ascites and venous blood of peritonitis rats using high performance liquid ...
山本, 雄治, 江端, 俊彰
core +1 more source
Leukotrienes as Modifiers of Preclinical Atherosclerosis? [PDF]
, 2012 Preclinical atherosclerosis represents a crucial period associated with several pathophysiological reactions in the vascular wall. Failure to diagnose preclinical atherosclerosis at this stage misses a major opportunity to prevent the long-term ...
Magnus Bäck, Graziano Riccioni
core +1 more source
Safety, Efficacy, and Mechanism of Action of Budesonide in Rhinitis and Rhinosinusitis: A Systematic Review. [PDF]
World J Otorhinolaryngol Head Neck SurgABSTRACT Objective Budesonide is a corticosteroid with unique pharmacokinetic and pharmacodynamic properties that has been a frontline treatment for patients with allergic rhinitis (AR) and chronic rhinosinusitis (CRS) since the 1990s. As research on budesonide continues to produce new insights, our aim was to synthesize recent investigations and ...
Kennedy DW, Cheng L, Wang DY.
europepmc +2 more sources
Montelukast Influence on Lung in Experimental Diabetes
MedicinaBackground and Objectives: The influence of montelukast (MK), an antagonist of cysLT1 leukotriene receptors, on lung lesions caused by experimental diabetes was studied.
Cristina Gales +3 more
doaj +1 more source
Current Approaches to the Choice of Basic Therapy for Mild Persistent Bronchial Asthma in Children
Zdorovʹe Rebenka, 2015 Objective of the Study: improving the treatment of mild persistent bronchial asthma based on the development of differential program for antiinflammatory therapy.
S.M. Nedelska +2 more
doaj +1 more source
Leukotrienes in cardiovascular disease
, 2001 Intensive research into the leukotrienes as inflammatory mediators in asthma has tended to overshadow the intriguing evidence suggesting their involvement in cardiovascular disease.
A P Sampson, Sampson, A. P.
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand +5 more
wiley +1 more source
Frontiers in NutritionNon-alcoholic steatohepatitis (NASH) is characterized by steatosis, inflammation, and hepatocyte damage. A Western-style diet characterized by excessive n-6 polyunsaturated fatty acid (n-6 PUFA) intake, which is metabolized to pro-inflammatory ...
Jian-Tong +10 more
doaj +1 more source
CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression
Advanced Science, EarlyView.A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao +27 more
wiley +1 more source
Production of peptide leukotrienes in endotoxin shock [PDF]
, 1985 Arachidonate metabolites are potent mediators generated in endotoxin shock. Following endotoxin administration (15 mgkg) into unanesthetized rats, we found a rapid biliary secretion of peptide leukotrienes.
Claudio Denzlinger +5 more
core +1 more source