Results 41 to 50 of about 28,774 (254)

BRONCHIAL OBSTRUCTION IN CHILDREN: A NEW SOLUTION TO AN OLD PROBLEM

Вопросы современной педиатрии, 2015
Bronchial obstruction is a widespread pathological condition in children. The development of this syndrome in bronchial asthma is caused by an allergic inflammation of the mucous membranes of the respiratory tract with the participation of leukotrienes ...
O. I. Simonova, Yu. V. Gorinova, A. A. Alekseeva, A. A. Tomilova   +3 more
doaj   +1 more source

Integration of Nutrition and Organic Agriculture Framework in Managing Gastrointestinal Nematodes in Ruminants

Animal Research and One Health, EarlyView.
Gastrointestinal nematode infections damage the gastrointestinal epithelial tissues of ruminants, affecting nutrient utilization and overall production performance. This review outlines host‐gastrointestinal nematode interactions and discusses integrated control strategies, including nutritional supplementation, grazing management, vaccines, and ...
Wenxun Chen, Xiangfang Tang, Yimin Zhuang, Shengjun Zhao, Ying Ren, Xiaokang Lv   +5 more
wiley   +1 more source

Navigating adverse immunostimulation: A practical guide for clinical researchers

British Journal of Clinical Pharmacology, EarlyView.
Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort, Anouk C. Meijs, Naomi B. Klarenbeek, Matthijs Moerland   +3 more
wiley   +1 more source

The Potential of Telomeric G-Quadruplexes Containing Modified Oligoguanosine Overhangs in Activation of Bacterial Phagocytosis and Leukotriene Synthesis in Human Neutrophils

Biomolecules, 2020
Human neutrophils are the first line of defense against bacterial and viral infections. They eliminate pathogens through phagocytosis, which activate the 5-lipoxygenase (5-LOX) pathway resulting in synthesis of leukotrienes.
Ekaterina A. Golenkina, Galina M. Viryasova, Nina G. Dolinnaya, Valeria A. Bannikova, Tatjana V. Gaponova, Yulia M. Romanova, Galina F. Sud’ina   +6 more
doaj   +1 more source

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

BMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang, Yu‐zhu Wang, Yi‐fei Wang, Que Bai, Jia‐xin Hao, Zhi‐ting Li, Xiao‐qing Cao, Yu Wei, Yue Feng, Ji‐hua Chen, Franklin R. Tay, Rui‐bing Wang, Jun‐ting Gu, Li‐na Niu   +13 more
wiley   +1 more source

A review of practical strategies for managing bronchial asthma in conventional medical systems

Indian Journal of Allergy Asthma and Immunology
Bronchial asthma is a chronic airway condition affecting about 10%–12% of adults and 15% of children worldwide. Treatment guidelines vary by asthma nature and severity.
Khadija Abdul Hafiz, Kaleem Ahmad, Mohd Aleemuddin Quamri   +2 more
doaj   +1 more source

Occupational asthma follow-up — Which markers are elevated in exhaled breath condensate and plasma?

International Journal of Occupational Medicine and Environmental Health, 2014
Objectives: To search for optimal markers in the exhaled breath condensate (EBC), plasma and urine that would reflect the activity/ severity of occupational asthma (OA) after the withdrawal from the exposure to the allergen. Material and Methods: Markers
Daniela Pelclová, Zdenka Fenclová, Štěpánka Vlčková, Pavlína Klusáčková, Jindřiška Lebedová, Kamila Syslová, Jaromír Běláček, Marek Kuzma, Tomáš Navrátil, Sergey Zakharov, Petr Kačer   +10 more
doaj   +1 more source

NSAID-Exacerbated Respiratory Disease (NERD): From Pathogenesis to Improved Care

Frontiers in Pharmacology, 2020
Nonsteroidal antiinflammatory drug (NSAID)-exacerbated respiratory disease (NERD) is characterized by moderate-to-severe asthma and a higher prevalence of chronic rhinosinusitis/nasal polyps, but is a highly heterogeneous disorder with various clinical ...
Seong-Dae Woo, Quoc Quang Luu, Quoc Quang Luu, Hae-Sim Park, Hae-Sim Park   +4 more
doaj   +1 more source

Effects of high‐moisture extrusion processing on reducing anti‐nutritional factors and allergenicity in plant‐based materials—A mini review

Food Biomacromolecules, EarlyView.
Abstract The rising demand for plant‐based meat alternatives has had advancements in processing technologies such as extrusion to meet consumer preferences for enhanced sensory qualities and nutritional benefits. High moisture extrusion (HME), a thermo‐mechanical process employing elevated moisture levels (40%–70%), has emerged as a promising method ...
Nur Hameedah Binte Ramadhan, Yuzhu Mao, Juan Du   +2 more
wiley   +1 more source

The features of bile acids exchange in rats under the influence of corvitin [PDF]

The Ukrainian Biochemical Journal, 2017
Corvitin is a soluble form of quercetin (QUE) and its effects are based on the ability to inhibit the activity of 5-lipoxygenase and to block the formation of leukotrienes.
T. V. Vovkun, P. I. Yanchuk, L. Ya. Shtanova, S. P. Veselskiy, N. B. Filimonova, A. S. Shalamay, V. G. Vedmid   +6 more
doaj   +1 more source