Results 41 to 50 of about 28,631 (145)

Métabolisme oxygéné des acides gras polyinsaturés et fonction dans les cellules sanguines et vasculaires1

Oléagineux, Corps gras, Lipides, 2011
Most polyunsaturated fatty acids have the minimal 1,4-cis,cis-pentadiene configuration to be oxygenated into a conjugated diene hydroperoxide. This product is usually reduced into the corresponding hydroxy derivative by cell glutathione peroxidases.
Lagarde Michel
doaj   +1 more source

Using high-performance liquid chromatography with UV detector to quantify exhaled leukotriene B4 level in nonatopic adults

Journal of the Formosan Medical Association, 2014
This study aimed to evaluate the feasibility of the chemical method to analyze exhaled breath condensate (EBC) leukotriene B4 (LTB4) level in humans.
Gwo-Hwa Wan, Dah-Chin Yan, Hui-Yun Tseng, Jian-Tao Lee, Yu-Wen Lin   +4 more
doaj   +1 more source

Very long-chain fatty acid accumulation causes lipotoxic response via 5-lipoxygenase in cerebral adrenoleukodystrophy

Journal of Lipid Research, 2010
Childhood adrenoleukodystrophy (cALD) is a metabolic disorder in which very long-chain fatty acids (VLCFA) accumulate due to ALD protein gene defects, ultimately leading to lipotoxicity-induced neuroinflammatory demyelinating disease.
Mushfiquddin Khan, Jaspreet Singh, Anne G. Gilg, Takuhiro Uto, Inderjit Singh   +4 more
doaj   +1 more source

Fatty acid binding protein 4/aP2-dependent BLT1R expression and signaling

Journal of Lipid Research, 2017
Previous studies have shown that reduced levels of the adipocyte fatty acid binding protein (FABP)4 (AFABP/aP2), result in metabolic improvement including potentiated insulin sensitivity and attenuated atherosclerosis.
Ann V. Hertzel, Hongliang Xu, Michael Downey, Nicholas Kvalheim, David A. Bernlohr   +4 more
doaj   +1 more source

LC/MS/MS analyses of open-flow microperfusion samples quantify eicosanoids in a rat model of skin inflammation[S]

Journal of Lipid Research, 2019
Eicosanoids are lipid-mediator molecules with key roles in inflammatory skin diseases, such as psoriasis. Eicosanoids are released close to the source of inflammation, where they elicit local pleiotropic effects and dysregulations.
Cornelia Pipper, Natalie Bordag, Bernadette Reiter, Kyriakos Economides, Peter Florian, Thomas Birngruber, Frank Sinner, Manfred Bodenlenz, Anita Eberl   +8 more
doaj   +1 more source

EICOSANOIDS AND INFLAMMATION

Современная ревматология, 2016
Inflammation is the most important element in the pathogenesis of major human diseases. It determines the fundamental value of anti-inflammatory therapy in the modern concept of targeted pathogenetic treatment.
A. E. Karateev, T. L. Aleinikova
doaj   +1 more source

Association of ambient air pollution and pesticide mixtures on respiratory inflammatory markers in agricultural communities

Environmental Research: Health
Air pollution exposure is associated with adverse respiratory health outcomes. Evidence from occupational and community-based studies also suggests agricultural pesticides have negative health impacts on respiratory health.
Matthew L Hughes, Grace Kuiper, Lauren Hoskovec, Sherry WeMott, Bonnie N Young, Wande Benka-Coker, Casey Quinn, Grant Erlandson, Nayamin Martinez, Jesus Mendoza, Greg Dooley, Sheryl Magzamen   +11 more
doaj   +1 more source

Leukotrienes in Asthma

, 2003
One of the major reasons for pursuing the chemical structure of the biological material known as slow-reacting substance of anaphylaxis (SRS-A) was that this material was known to be a potent bronchoconstrictor substance in guinea pigs [1] and in isolated human airways [2].
openaire   +2 more sources

Cysteine leukotrienes as key mediators of immune-dependent diseases and the therapeutic potential of the leukotriene receptor antagonist (montelukast). Part 2

Лечащий Врач
Background. Cysteine leukotrienes are lipid mediators formed upon activation of the 5-lipoxygenase pathway of arachidonate metabolism. These are universal mediators with a wide spectrum of action, affecting almost all aspects of mammalian biology.
N. G. Astafieva, I. E. Mikhailova, E. O. Gaisina, I. A. Perfilova, E. N. Udovichenko   +4 more
doaj   +1 more source

Kounis Syndrome Features in Special Populations. [PDF]

Med Sci (Basel)
Ceasovschih A, Kounis NG, Markos S, Ejubovic M, Cherska M, Barkas F, Ristovski V, Corlateanu A, Sivapalan P, Kotlyarov S, Sorodoc V, Sorodoc L.   +11 more
europepmc   +1 more source