Results 21 to 30 of about 35,647 (293)
eLife, 2013 Dengue Virus (DENV), a flavivirus spread by mosquito vectors, can cause vascular leakage and hemorrhaging. However, the processes that underlie increased vascular permeability and pathological plasma leakage during viral hemorrhagic fevers are largely ...
Ashley L St John +4 more
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Frontiers in Immunology, 2022 The pathological implications of tumor-associated macrophages in the glioma microenvironment have been highlighted, while there lacks a gene signature to characterize the functional status and clinical implications of these cells.
Hang Ji +24 more
doaj +1 more source
NSAIDs and Acute Pancreatitis: A Systematic Review
Pharmaceuticals, 2010 The resulting pain is the main symptom of acute pancreatitis and it should be alleviated as soon as possible. NSAIDs are the first line therapy for pain and they are generally administered to acute pancreatitis patients upon admission to the hospital. In
Roberto Corinaldesi +2 more
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Journal of Lipid Research, 2021 Leukotrienes (LTs) and sphingolipids are critical lipid mediators participating in numerous cellular signal transduction events and developing various disorders, such as bronchial hyperactivity leading to asthma. Enzymatic reactions initiating production
Viktor Bugajev +15 more
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気管支喘息患者における白血球ロイコトリエン産生能に対する不飽和脂肪酸食の効果に影響する因子 [PDF]
, 1999 Dietary supplementation with perilla seed oil, a vegetable oil rich in α -lin- olenic acid, inhibits the generation of leukotrienes(LTs) by leucocytes in patients with bronchial asthma. We examined the factors that affect the suppression of LT generation
Hosaki, Yasuhiro +11 more
core +1 more source
Frontiers in Pharmacology, 2023 Lipoxygenases (LOX) transform arachidonic acid (AA, C20:4) and docosahexaenoic acid (DHA, C22:6) into bioactive lipid mediators (LMs) that comprise not only pro-inflammatory leukotrienes (LTs) but also the specialized pro-resolving mediators (SPMs) that ...
Philipp Dahlke +5 more
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, 1983 The leukotrienes and the related hydroxy acids constitute a chemically and biologically rather heterogenous group of compounds. Thus, the assay methods employed for their detection and quantification by necessity differ considerably, depending on what ...
Hansson, G +5 more
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Pulmonary and Cardiovascular Pharmacology of Leukotrienes
, 1983 Leukotrienes rapidly gained widespread recognition as substances of potentially great impact when slow reacting substance of anaphylaxis (SRS-A) was shown to be included in this newly discovered family of arachidonic acid derivatives (Murphy et al ...
Sven-Erik Dahlén +5 more
core +1 more source
Post-transcriptional regulation of 5-lipoxygenase mRNA expression via alternative splicing and nonsense-mediated mRNA decay [PDF]
, 2012 5-Lipoxygenase (5-LO) catalyzes the two initial steps in the biosynthesis of leukotrienes (LT), a group of inflammatory lipid mediators derived from arachidonic acid.
Laura Pufahl (182448) +26 more
core +2 more sources
Biosynthesis and Metabolism of Leukotrienes
, 1983 Leukotriene biosynthesis has until today been detected in several biological systems (Table I) using different kinds of stimuli: ionophore A23187, the bacterial peptide f-Met-Leu-Phe (fMLP), antigen-antibody interactions, phagocytic stimuli, and, not to ...
Westlund, P +3 more
core +1 more source