Results 21 to 30 of about 68,425 (301)
Cytokine-Leukotriene Receptor Interactions
Biochemical and pharmacological studies have identified the structure of leukotrienes, the pathways that lead to their synthesis, and the signaling events they trigger when they interact with their cognate receptors.
Marek Rola-Pleszczynski, Jana Stankova
doaj +1 more source
Cytoplasmic lipid bodies in eosinophils: Central roles in eicosanoid generation
Lipid bodies are non-membrane bound, lipid-rich cytoplasmic inclusions that form in diverse cell types. Characteristically, lipid body numbers increase when eosinophils and other leukocytes are participating in inflammatory processes.
Peter F Weller +3 more
doaj +1 more source
Dengue Virus (DENV), a flavivirus spread by mosquito vectors, can cause vascular leakage and hemorrhaging. However, the processes that underlie increased vascular permeability and pathological plasma leakage during viral hemorrhagic fevers are largely ...
Ashley L St John +4 more
doaj +1 more source
Effects of inflammation in dental pulp cell differentiation and reparative response
The responsiveness of the dentin–pulp complex is possible due to the stimulation of dental pulp cells, which begin to synthesize and secrete dentin matrix.
Francine Lorencetti-Silva +6 more
doaj +1 more source
Protective effect of leukotriene receptor antagonist montelukast on smoking-induced lung injury in Wistar rats. [PDF]
Increased activation of alveolar macrophage, neutrophil and mast cell has been proven in cigarette smoking (CS)-related lung disorders (CSLD). An increased production of cysteinyl-leukotrienes (LTs), which are mediators secreted from the mentioned cells,
Coskun, Senol +3 more
core +1 more source
NSAIDs and Acute Pancreatitis: A Systematic Review
The resulting pain is the main symptom of acute pancreatitis and it should be alleviated as soon as possible. NSAIDs are the first line therapy for pain and they are generally administered to acute pancreatitis patients upon admission to the hospital. In
Roberto Corinaldesi +2 more
doaj +1 more source
Human neutrophils are the first line of defense against bacterial and viral infections. They eliminate pathogens through phagocytosis, which activate the 5-lipoxygenase (5-LOX) pathway resulting in synthesis of leukotrienes.
Ekaterina A. Golenkina +6 more
doaj +1 more source
Amyloid proteotoxicity initiates an inflammatory response blocked by cannabinoids. [PDF]
The beta amyloid (Aβ) and other aggregating proteins in the brain increase with age and are frequently found within neurons. The mechanistic relationship between intracellular amyloid, aging and neurodegeneration is not, however, well understood.
Currais, Antonio +5 more
core +2 more sources
NSAID-Exacerbated Respiratory Disease (NERD): From Pathogenesis to Improved Care
Nonsteroidal antiinflammatory drug (NSAID)-exacerbated respiratory disease (NERD) is characterized by moderate-to-severe asthma and a higher prevalence of chronic rhinosinusitis/nasal polyps, but is a highly heterogeneous disorder with various clinical ...
Seong-Dae Woo +4 more
doaj +1 more source
Matrikines are key regulators in modulating the amplitude of lung inflammation in acute pulmonary infection [PDF]
Bioactive matrix fragments (matrikines) have been identified in a myriad of disorders, but their impact on the evolution of airway inflammation has not been demonstrated.
Snelgrove, RJ
core +1 more source

