Results 21 to 30 of about 68,425 (301)

Cytokine-Leukotriene Receptor Interactions

open access: yesThe Scientific World Journal, 2007
Biochemical and pharmacological studies have identified the structure of leukotrienes, the pathways that lead to their synthesis, and the signaling events they trigger when they interact with their cognate receptors.
Marek Rola-Pleszczynski, Jana Stankova
doaj   +1 more source

Cytoplasmic lipid bodies in eosinophils: Central roles in eicosanoid generation

open access: yesAllergology International, 1997
Lipid bodies are non-membrane bound, lipid-rich cytoplasmic inclusions that form in diverse cell types. Characteristically, lipid body numbers increase when eosinophils and other leukocytes are participating in inflammatory processes.
Peter F Weller   +3 more
doaj   +1 more source

Contributions of mast cells and vasoactive products, leukotrienes and chymase, to dengue virus-induced vascular leakage

open access: yeseLife, 2013
Dengue Virus (DENV), a flavivirus spread by mosquito vectors, can cause vascular leakage and hemorrhaging. However, the processes that underlie increased vascular permeability and pathological plasma leakage during viral hemorrhagic fevers are largely ...
Ashley L St John   +4 more
doaj   +1 more source

Effects of inflammation in dental pulp cell differentiation and reparative response

open access: yesFrontiers in Dental Medicine, 2022
The responsiveness of the dentin–pulp complex is possible due to the stimulation of dental pulp cells, which begin to synthesize and secrete dentin matrix.
Francine Lorencetti-Silva   +6 more
doaj   +1 more source

Protective effect of leukotriene receptor antagonist montelukast on smoking-induced lung injury in Wistar rats. [PDF]

open access: yes, 2003
Increased activation of alveolar macrophage, neutrophil and mast cell has been proven in cigarette smoking (CS)-related lung disorders (CSLD). An increased production of cysteinyl-leukotrienes (LTs), which are mediators secreted from the mentioned cells,
Coskun, Senol   +3 more
core   +1 more source

NSAIDs and Acute Pancreatitis: A Systematic Review

open access: yesPharmaceuticals, 2010
The resulting pain is the main symptom of acute pancreatitis and it should be alleviated as soon as possible. NSAIDs are the first line therapy for pain and they are generally administered to acute pancreatitis patients upon admission to the hospital. In
Roberto Corinaldesi   +2 more
doaj   +1 more source

The Potential of Telomeric G-Quadruplexes Containing Modified Oligoguanosine Overhangs in Activation of Bacterial Phagocytosis and Leukotriene Synthesis in Human Neutrophils

open access: yesBiomolecules, 2020
Human neutrophils are the first line of defense against bacterial and viral infections. They eliminate pathogens through phagocytosis, which activate the 5-lipoxygenase (5-LOX) pathway resulting in synthesis of leukotrienes.
Ekaterina A. Golenkina   +6 more
doaj   +1 more source

Amyloid proteotoxicity initiates an inflammatory response blocked by cannabinoids. [PDF]

open access: yes, 2016
The beta amyloid (Aβ) and other aggregating proteins in the brain increase with age and are frequently found within neurons. The mechanistic relationship between intracellular amyloid, aging and neurodegeneration is not, however, well understood.
Currais, Antonio   +5 more
core   +2 more sources

NSAID-Exacerbated Respiratory Disease (NERD): From Pathogenesis to Improved Care

open access: yesFrontiers in Pharmacology, 2020
Nonsteroidal antiinflammatory drug (NSAID)-exacerbated respiratory disease (NERD) is characterized by moderate-to-severe asthma and a higher prevalence of chronic rhinosinusitis/nasal polyps, but is a highly heterogeneous disorder with various clinical ...
Seong-Dae Woo   +4 more
doaj   +1 more source

Matrikines are key regulators in modulating the amplitude of lung inflammation in acute pulmonary infection [PDF]

open access: yes, 2015
Bioactive matrix fragments (matrikines) have been identified in a myriad of disorders, but their impact on the evolution of airway inflammation has not been demonstrated.
Snelgrove, RJ
core   +1 more source

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