Results 31 to 40 of about 68,425 (301)

The features of bile acids exchange in rats under the influence of corvitin [PDF]

The Ukrainian Biochemical Journal, 2017
Corvitin is a soluble form of quercetin (QUE) and its effects are based on the ability to inhibit the activity of 5-lipoxygenase and to block the formation of leukotrienes.
T. V. Vovkun, P. I. Yanchuk, L. Ya. Shtanova, S. P. Veselskiy, N. B. Filimonova, A. S. Shalamay, V. G. Vedmid   +6 more
doaj   +1 more source

Role of Mitochondria in the Regulation of Effector Functions of Granulocytes

Cells, 2023
Granulocytes (neutrophils, eosinophils, and basophils) are the most abundant circulating cells in the innate immune system. Circulating granulocytes, primarily neutrophils, can cross the endothelial barrier and activate various effector mechanisms to ...
Nina V. Vorobjeva, Maria A. Chelombitko, Galina F. Sud’ina, Roman A. Zinovkin, Boris V. Chernyak   +4 more
doaj   +1 more source

高齢者気管支喘息における気道過敏性と温泉療法 [PDF]

, 2001
Clinical effects of spa therapy were examined in 150 patients with asthma in relation tobronchial hyperresponsiveness and patient age. 1. The efficacy rate of spa therapy was larger as the patient age was higher: the rate was 73.3% in patients under age ...
Ashida, Kozo, Hosaki, Yasuhiro, Mifune, Takashi, Mitsunobu, Fumihiro, Ochi, Koji, Okamoto, Makoto, Takata, Shingo, Tanizaki, Yoshiro, Tsugeno, Hirofumi   +8 more
core   +1 more source

n-3系脂肪散を強化した食事療法が有効と考えられた肺気腫の一例 [PDF]

, 1998
An effective treatment for the advanced stages of chronic obstructive pulmonary disease (COPD) has not been established yet. We report our recent experience of one patient with pulmonary emphysema treated by dietary supplementation of n-3 fatty acid for ...
Ashida, Kozo, Hosaki, Yasuhiro, Mifune, Takashi, Mitsunobu, Fumihiro, Okamoto, Makoto, Tanizaki, Yoshiro, Tsugeno, Hirofumi, Tsuji, Takao   +7 more
core   +1 more source

Current Approaches to the Choice of Basic Therapy for Mild Persistent Bronchial Asthma in Children

Zdorovʹe Rebenka, 2015
Objective of the Study: improving the treatment of mild persistent bronchial asthma based on the development of differential program for antiinflammatory therapy.
S.M. Nedelska, O.D. Kuznietsova, K.V. Raskina   +2 more
doaj   +1 more source

Knock-In Mice Expressing a 15-Lipoxygenating Alox5 Mutant Respond Differently to Experimental Inflammation Than Reported Alox5^−/− Mice

Metabolites, 2021
Arachidonic acid 5-lipoxygenase (ALOX5) is the key enzyme in the biosynthesis of pro-inflammatory leukotrienes. We recently created knock-in mice (Alox5-KI) which express an arachidonic acid 15-lipoxygenating Alox5 mutant instead of the 5-lipoxygenating ...
Eugenia Marbach-Breitrück, Nadine Rohwer, Carmen Infante-Duarte, Silvina Romero-Suarez, Dominika Labuz, Halina Machelska, Laura Kutzner, Nils Helge Schebb, Michael Rothe, Pallu Reddanna, Karsten H. Weylandt, Lothar H. Wieler, Dagmar Heydeck, Hartmut Kuhn   +13 more
doaj   +1 more source

Integrating evidence for managing asthma in patients who smoke [PDF]

, 2014
Peer reviewedPublisher ...
Bjermer, Leif, Chisholm, Alison, Popov, Todor A, Price, David   +3 more
core   +1 more source

Targeting the PGRN‐BMP Lysosomal Axis With NPs@PGRN Reverses Immunometabolic Dysfunction in Chronic Septic Arthritis

Advanced Science, EarlyView.
Chronic septic arthritis involves intracellular bacterial persistence and lipid‐immune crosstalk via the PGRN‐BMP lysosomal axis. A dual‐targeting nanoparticle system (NPs@PGRN) restores lysosomal bactericidal function, reduces bacterial burden, and reprograms macrophage immunity, offering a novel therapeutic strategy. ABSTRACT Chronic septic arthritis,
Congsun Li, Jiaqi Fan, Tao Sun, Wushi Cui, Jiaxuan Zou, Weinan Yang, Liang Chen, Jian Xiao, Shicheng Wang, Tao Zhang, Jianqiao Hong, An Liu, Haobo Wu   +12 more
wiley   +1 more source

The role of leukotrienes in the pathogenesis of systemic sclerosis

Folia Histochemica et Cytobiologica, 2012
Systemic sclerosis (SSc, scleroderma) is an autoimmune disease characterized by widespread vascular injury and progressive fibrosis of the skin and internal organs.
Sylwia Chwieśko-Minarowska, Krzysztof Kowal, Marek Bielecki, Otylia Kowal-Bielecka   +3 more
doaj   +1 more source

Stimulus specificity of the generation of leukotrienes by dog mastocytoma cells. [PDF]

, 1983
Isolated dog mastocytoma cells sensitized with dog anti-ragweed IgE and challenged with ragweed antigen or incubated with ionophore A23187 or the carboxy-terminal dodecapeptide of platelet factor 4, PF4(59-70), release histamine and concurrently generate
Goetzl, EJ, Gold, WM, Phillips, MJ
core