Ekbom Spectrum Psychosis Associated with 24-hour Continuous Subcutaneous Foslevodopa/Foscarbidopa Infusion in Parkinson's Disease. [PDF]
Meloni M +6 more
europepmc +1 more source
Abstract Background Remote programming of deep brain stimulation may improve access to specialized postoperative care for people with Parkinson's disease, but prospective randomized evidence remains limited. Objective We aimed to determine whether remote follow‐up programming after standardized inpatient initiation is noninferior to conventional in ...
Juhi Shaik +16 more
wiley +1 more source
Long-term safety profile of opicapone in patients with Parkinson's disease and early fluctuations. [PDF]
Ferreira JJ +12 more
europepmc +1 more source
Abstract Background Cognitive impairment is a prevalent and debilitating feature of Parkinson's disease (PD). Increasing evidence from postmortem and in vivo positron emission tomography imaging studies supports cholinergic dysfunction in PD. There is, however, little evidence regarding the influence of the structural integrity of cortical cholinergic ...
Nicola M. Slater +13 more
wiley +1 more source
Real-World Use of Opicapone in Management of Patients with Parkinson's Disease and Early Motor Fluctuations in Spain: 12-Month Interim Analysis of REONPARK Study. [PDF]
López-Manzanares L +16 more
europepmc +1 more source
Cross‐Cohort Evidence Links KCNJ6 rs702859 to Impulsive–Compulsive Phenotypes in Parkinson's Disease
Abstract Background Impulse control disorders (ICDs) and related compulsive behaviors (CBs) are frequent non‐motor complications of Parkinson's disease (PD) with a probable genetic contribution. Objective To investigate whether genetic variants involved in reward and punishment processing are associated with impulsive–compulsive phenotypes in PD ...
Sergio García‐Díaz +21 more
wiley +1 more source
Abstract The neuropathology of Parkinson's disease (PD) is characterized in part by the degeneration of catecholaminergic neurons, particularly dopaminergic neurons in the substantia nigra pars compacta (SNpc) and noradrenergic neurons in the locus coeruleus (LC), yet no validated in vivo biomarker quantifies this process.
Rayo Akande +5 more
wiley +1 more source
Long-Term Clinical Efficacy, Safety, and Polypharmacy Simplification of Levodopa-Entacapone-Carbidopa Intestinal Gel in Advanced Parkinson's Disease: An 18-Month Longitudinal Study. [PDF]
Orbán-Kis K +14 more
europepmc +1 more source
Therapeutic Impact of GLP‐1 Receptor Agonists on Parkinson's Disease: A Scoping Review
ABSTRACT No disease‐modifying treatment exists for Parkinson's disease (PD). Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have gained attention as promising candidates for neuroprotection, given documented expression of GLP‐1 receptors within the central nervous system and the contribution of brain insulin resistance to dopaminergic ...
João Pedro Henriques +4 more
wiley +1 more source
Continuous Subcutaneous Foslevodopa/Foscarbidopa Improves Nonmotor Symptoms and Fluctuations in Parkinson's Disease. [PDF]
De Micco R +6 more
europepmc +1 more source

