Results 181 to 190 of about 69,629 (300)

The impact of levodopa on post-stroke depression: the ESTREL-depression-study. [PDF]

Eur Stroke J
Sauter MI, Kaufmann JE, Boos L, Zietz A, Trüssel S, Luft AR, Polymeris A, Altersberger VL, Wiesner K, Wiegert M, Held JPO, Rottenberger Y, Schwarz A, Medlin F, Accolla EA, Foucras S, Kägi G, De Marchis GM, Politz S, Greulich M, Tarnutzer AA, Sturzenegger R, Katan M, Arnold M, Nedeltchev K, Schär J, Deglon KVDK, Rapin PA, Salerno A, Seiffge DJ, Auer E, Lippert J, Bonati LH, Schuster-Amft C, Gäumann S, Chabwine JN, Humm A, Möller JC, Schweinfurther R, Bujan B, Jedrysiak P, Sandor PS, Gonzenbach R, Mylius V, Lutz D, Lienert C, Peters N, Michel P, Müri RM, Schädelin S, Hemkens LG, Ford GA, Lyrer PA, Gensicke H, Traenka C, Engelter ST.   +55 more
europepmc   +1 more source

Expanding the Phenotype of PARK‐PRKN to Spastic Paraplegia: A Report of Two Cases

Movement Disorders Clinical Practice, EarlyView.
Nicolas Geoffre, Thomas Ollivier, Guillaume Baille, Luc Defebvre, Vincent Huin, Eugenie Mutez   +5 more
wiley   +1 more source

A feasibility open-label clinical trial utilizing second-generation artificial intelligence based on the constrained-disorder principle in patients with Parkinson's disease. [PDF]

IBRO Neurosci Rep
Lehmann H, Azmanov H, Hershkovitz Y, Hurvitz N, Agus S, Berg M, Arkadir D, Ilan Y.   +7 more
europepmc   +1 more source

Elevation of Stearoyl‐Coenzyme A Desaturase and Monounsaturated Fatty Acids in Parkinson's Disease Serum

Movement Disorders, EarlyView.
Abstract Background Emerging evidence indicates that dysregulation of monounsaturated fatty acids (MUFAs), synthesized by the enzyme stearoyl‐coenzyme A desaturase (SCD), impacts on α‐synuclein pathology in the Parkinson's disease (PD) brain. Objective The objective of this study was to analyze SCD and MUFA‐enriched lipids in the periphery of patients ...
Finula I. Isik, Russell Pickford, Michelle Chua, Simon J.G. Lewis, Nicolas Dzamko, Woojin Scott Kim   +5 more
wiley   +1 more source

Long‐Term Outcomes of Deep Brain Stimulation in Woodhouse–Sakati Syndrome

Movement Disorders, EarlyView.
Abstract Background Woodhouse–Sakati syndrome (WSS) is a rare autosomal recessive disease with distinctive neuroendocrine manifestations, with dystonia being the most common. No clear guidelines are available for the treatment of dystonia in WSS. Objective The aim was to analyze the impact of deep brain stimulation (DBS) on WSS‐associated dystonia ...
Hend Alhodaif, Yara Alkhodair, Faisal Alotaibi, Salma Alqahtani, Saeed Bohlega, Amaal Aldakheel   +5 more
wiley   +1 more source

Cerebrospinal fluid dopamine 3-O-sulfate as a novel biomarker for predicting motor complications in Parkinson's disease: insights from the PPMI cohort. [PDF]

J Transl Med
Chi J, Yang R, Zhang P, Rong S, Cai M, Zhang Y.   +5 more
europepmc   +1 more source

Temporal Dynamics of Parkinson's Disease Tremor: Clinical and Neuroimaging Insights

Movement Disorders, EarlyView.
Abstract Background Parkinson's disease (PD) is a progressive neurodegenerative disorder clinically defined by three cardinal motor symptoms: bradykinesia, rigidity, and tremor. Although the natural history of bradykinesia and rigidity is well described, the evolution of tremor as the disease progresses remains controversial. Objectives The goal was to
Melanie Suette, Robert Matic, Marisa Koini, Lukas Gattermeyer‐Kell, Daniela Kern, Petra Katschnig‐Winter, Mariella Koegl, Maximilian Sackl, Christian Tinauer, Birgit Helmlinger, Manuel Leitner, Stefan Ropele, Daniela Pinter, Christian Enzinger, Stephan Seiler, Petra Schwingenschuh   +15 more
wiley   +1 more source

Clinical characteristics of Parkinson's disease in the outpatient clinic of a regional hospital in Peru. [PDF]

Rev Peru Med Exp Salud Publica
Centeno-Arispe JJ, Hurtado-González CA, Murillo-Salas AP, Camargo-Salazar IP, Lizarraga-Mendoza KJ.   +4 more
europepmc   +1 more source

Conditional Modeling of GNAO1 Disorder Dissociates Circuit Specific Contributions to Pathology and Rationalizes Ameliorative Strategies

Movement Disorders, EarlyView.
Abstract Background Neurodevelopmental disorders feature various symptoms that frequently include seizures and motor manifestations, but their attribution to disruptions of specific circuits and molecular alterations is notoriously hard to establish, which limits therapeutic interventions.
Gloria Brunori, Stefano Zucca, Colten K. Lankford, Yi‐Zhi Wang, Marianna Franco, Nina A. Alekseeva, Sevinj Ahmedova, Han My Van, Jeffrey N. Savas, Kirill A. Martemyanov   +9 more
wiley   +1 more source

Tavapadon as Adjunctive Treatment for Parkinson Disease: The TEMPO-3 Randomized Clinical Trial.

JAMA Neurol
Fernandez HH, Isaacson SH, Hauser RA, Agarwal P, Ondo W, Park A, Kremens D, Leoni M, Duvvuri S, Combs C, Koenig E, Chang I, Pastino G, Tringali S, Golonski N, Sanchez R, Harmer L, Boiser J, Zadikoff C, Mari Z.   +19 more
europepmc   +1 more source