Results 161 to 170 of about 53,685 (285)

Peripheral Neuropathy in Parkinson's Disease Treated with Device-Assisted Therapies: How Often It Is Reported Depends on How It Is Sought. A Systematic Review and Meta-Analysis. [PDF]

Biomedicines
Blidaru N, Tulbă D, Blidaru TC, Stoleru AM, Constantinescu AM, Popescu ME, Garofil DN, Popescu BO.   +7 more
europepmc   +1 more source

German Delphi consensus: COMT inhibitors in the management of wearing-off fluctuations in Parkinson's disease. [PDF]

J Neural Transm (Vienna)
Jost WH, Müller R, Schüle R, Storch A, Witt K, Tönges L.   +5 more
europepmc   +1 more source

GCH1 p.Ser80Asn Confers Risk for Parkinson's Disease in East Asian Populations

Movement Disorders, EarlyView.
Abstract Introduction GCH1 has been implicated in Parkinson's disease (PD), but its risks variants and associations are not well defined. Objectives Our goal was to investigate the clinical relevance and PD risk associated with the GCH1 p.Ser80Asn variant.
Yi Wen Tay, Andrew Leslie Lee, Jie Ping Schee, Chin‐Hsien Lin, Eng King Tan, Jung Hwan Shin, Pin‐Shiuan Chen, Sung‐Pin Fan, Cheng‐Hsuan Li, Ebonne Yu Lin Ng, Han Joon Kim, Beomseok Jeon, Sulev Koks, Huyen Thi Thanh Vu, Kin Ying Mok, Yi Ting Lim, Mohd Salahuddin Kamaruddin, Tzi Shin Toh, Hans Xing Ding, Anis Nadhirah Khairul Anuar, Norlisah Ramli, Ignacio J. Keller Sarmiento, Maria Teresa Periñan, Zih‐Hua Fang, Lara M. Lange, Kishore R. Kumar, Soraya Bardien, Joanne Trinh, Enza Maria Valente, SG10K_Health Consortium, the Global Parkinson's Genetics Program (GP2), Peter Heutink, Katja Lohmann, Christine Klein, Niccolò E. Mencacci, Shen‐Yang Lim, Azlina Ahmad‐Annuar, Ai Huey Tan   +37 more
wiley   +1 more source

Psychotic symptoms in tyrosine hydroxylase deficiency-associated dopa-responsive dystonia treated with antipsychotics and rTMS: a case report. [PDF]

Front Psychiatry
Shen Y, Chen HZ, Lv L, Fang LL.
europepmc   +1 more source

Ursodeoxycholic Acid and Parkinson's Disease Risk: An Emulated Target Trial in UK Electronic Health Records

Movement Disorders, EarlyView.
Abstract Background Ursodeoxycholic acid (UDCA) has shown mitochondrial and neuroprotective effects and has been proposed as a treatment for Parkinson's disease (PD). However, population‐level evidence on its effect on PD risk is lacking. Objectives To compare the risk of incident PD among UDCA initiators versus matched non‐initiators within a ...
Chengsheng Ju, Anette Schrag, Camille Carroll, Xi Xiong, James Carpenter, Oliver Bandmann, Thomas Foltynie, Li Wei   +7 more
wiley   +1 more source

Levodopa-induced dyskinesia provokes inflexible head-pelvis coordination during standing in Parkinson's disease. [PDF]

Clin Biomech (Bristol)
Aderonmu JA, Dotov D, Curtze C.
europepmc   +1 more source

Lysosomal Expression Profile in Plasma Associates with Disease Severity in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Parkinson's disease (PD) is a clinically and biologically heterogeneous neurodegenerative disorder, driven by multiple mechanisms among which are lysosomal and mitochondrial dysfunction. Here, we explored blood‐based lysosomal and mitochondrial profiles in relation to PD diagnosis and severity.
Janna van Wetering, Manon M. van Ingen, Evelien Timmermans, Sjors G.J.G. in't Veld, Henk W. Berendse, Charlotte E. Teunissen, Wilma D.J. van de Berg   +6 more
wiley   +1 more source

Long-Duration Response to Levodopa in Patients with Early Parkinson's Disease: Pharmacodynamics, Neuroplasticity, and Clinical Implications. [PDF]

Biomedicines
Sciacca G.
europepmc   +1 more source

Striatal Dopaminergic Reserve Shapes the Longitudinal Impact of Peripheral Immune Activation on Motor Progression in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Peripheral immune dysregulation has been implicated in Parkinson's disease (PD) progression, but whether motor deterioration reflects accelerated nigrostriatal degeneration or residual dopaminergic reserve remains unclear. Objectives To examine whether baseline and time‐varying neutrophil‐to‐lymphocyte ratio (NLR) relate to motor ...
Osman Kahveci, Ulaş Ay, Tamer Demiralp
wiley   +1 more source

Directional Adaptive Deep Brain Stimulation: An Initial Report of Safety, Tolerability, and Effectiveness

Movement Disorders, EarlyView.
Abstract Background Adaptive deep brain stimulation (aDBS) is a safe and effective therapy for people with Parkinson's disease (PWP). Utilization of directional aDBS has not been specifically evaluated. Objectives The goal is to report the first data on the safety, tolerability, and preliminary effectiveness of chronic, directional aDBS in PWP ...
Martijn Beudel, Todd M. Herrington, Simon Little, Jill L. Ostrem, Leonardo Almeida, Adolfo Ramirez‐Zamora, Alfonso Fasano, Travis Hassell, Kyle T. Mitchell, Elena Moro, Michal Gostkowski, Scott Stanslaski, Rebekah L.S. Summers, Tim J. Goble, Robert S. Raike, Lisa Tonder, Ye Tan, Helen Bronte‐Stewart, on behalf of the ADAPT‐PD Trial Investigators   +18 more
wiley   +1 more source