Results 141 to 150 of about 53,685 (285)

AMPA receptor blockade improves levodopa-induced dyskinesia in MPTP monkeys

, 2000
OBJECTIVE: To evaluate the contribution of amino-3-hydroxy-5-methyl-4-isoxazole proprionic acid (AMPA) glutamate receptors to the pathogenesis of parkinsonian signs and levodopa-induced dyskinesias. BACKGROUND: Motor fluctuations and dyskinesias reflect,
Blanchet, P. J., Verhagen, L., Chase, T. N., Lamers, E., Konitsiotis, S.   +4 more
core  

COVID‐19 Amplifies Sex‐Specific Dopamine and Glial Responses in a Parkinson's Disease Mouse Model

Movement Disorders, EarlyView.
Abstract Background Exposure to environmental agents, including viral infections, may increase Parkinson's disease (PD) susceptibility, especially in males, but the neurodegenerative risk extent of COVID‐19 remains uncertain. Objectives We investigated the plausible link between severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection and
Ifeoluwa Awogbindin, Mélanie Bourque, Marc Morissette, Marie‐Ève Hamelin, Chantal Rhéaume, Jared VanderZwaag, Antonia Landwehr, Disha Patel, Guy Boivin, Marie‐Ève Tremblay, Thérèse Di Paolo   +10 more
wiley   +1 more source

Apathy in Lewy Body Disorders: A Position Paper

Movement Disorders, EarlyView.
Abstract Apathy is one of the most prevalent and disabling non‐motor symptoms in Parkinson's disease (PD) and dementia with Lewy bodies (DLB), collectively referred to as Lewy body disorders (LBDs). It is associated with reduced quality of life, accelerated cognitive decline, increased caregiver burden, and poorer functional outcomes, yet remains ...
Jaime Kulisevsky, Lidia Bojtos, Milica G. Kramberger, Elisa Mantovani, Iulia Murasan, Jose‐Alberto Palma, Karolina Poplawska‐Domaszewicz, Anna Sauerbier, Kallol Ray Chaudhuri, Per Odin, Daniel Weintraub, Anette Schrag, Cristian Falup‐Pecorariu   +12 more
wiley   +1 more source

Impact of type 2 diabetes mellitus on acute levodopa responsiveness in Parkinson's disease: A Multicenter retrospective study. [PDF]

Clin Park Relat Disord
Stockmann O, Ye L, Buhmann C, Maass F, van Riesen C, Weinrich C, Wegner F, Höllerhage M, Pötter-Nerger M, Klietz M.   +9 more
europepmc   +1 more source

The Costs of Parkinson's Disease in Europe: Results of the Costs of Illness in Neurology Initiative

Movement Disorders, EarlyView.
Abstract Background Parkinson's disease (PD) is the second most common neurodegenerative disease. It imposes substantial and growing burden on patients, families, and caregivers and reduces quality of life. The disability and care needs associated with PD carry economic ramifications.
Luisa Welter, Christopher Kruse, Mateo Montes‐Martinez, Paul Boon, Claudio Bassetti, Thomas Berger, Elena Moro, Maria Konti, Maria Lolich, Alessandro Tessitore, Amelia Hursey, Marjan Arvandi, Nikolai Mühlberger, Uwe Siebert, Richard Dodel, Günther Deuschl   +15 more
wiley   +1 more source

Differential Temporal Dynamics and Motor-Non-Motor Dissociation After Inhaled Levodopa in Parkinson's Disease: A Post Hoc Analysis of the INLEVO-LIFE PD Study. [PDF]

Med Sci (Basel)
Santos García D, Cerdán Sánchez M, Yáñez Baña R, Cabo I, Cimas Hernando MI.   +4 more
europepmc   +1 more source

Decoding Sleep Architecture from Ambulatory Basal Ganglia Signals in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Sleep architecture and circadian rhythms are frequently disrupted in Parkinson's disease (PD). BrainSense‐enabled neurostimulators combined with wearable technology enable chronic assessment of nocturnal brain activity, with potential for future diagnostics and personalized treatments. Objectives To neurophysiologically characterize
Alberto Averna, Elena Bernasconi, Aaron Colombo, Laura Alva, Mario Sousa, Michael Schuepbach, Ines Debove, Georg Kägi, Andreas Nowacki, Claudio Pollo, Lenard Lachenmayer, Paul Krack, Syed Ahmar Shah, Damian Marc Herz, Benoit Duchet, Gerd Tinkhauser   +15 more
wiley   +1 more source

Directional Deep Brain Stimulation for Parkinson's Disease: Results of an International Crossover Study With Randomized, Double‐Blind Primary Endpoint

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objective Published reports on directional deep brain stimulation (DBS) have been limited to small, single‐center investigations. Therapeutic window (TW) is used to describe the range of stimulation amplitudes achieving symptom relief without side effects.
Alfons Schnitzler, Pablo Mir, Matthew A. Brodsky, Leonard Verhagen, Sergiu Groppa, Ramiro Alvarez, Andrew Evans, Marta Blazquez, Sean Nagel, Julie G. Pilitsis, Monika Pötter‐Nerger, Winona Tse, Leonardo Almeida, Nestor Tomycz, Joohi Jimenez‐Shahed, Witold Libionka, Fatima Carrillo, Christian J. Hartmann, Stefan Jun Groiss, Martin Glaser, Florence Defresne, Edward Karst, Binith Cheeran, Jan Vesper, for the PROGRESS Study Investigators   +24 more
wiley   +1 more source

Influence of Dietary Protein on Levodopa Effectiveness

In adult patients with Parkinson\u27s disease how does carbidopa-levodopa administration with protein vs without protein impact levodopa absorption and patient signs and symptoms?https://knowledgeconnection.mainehealth.org/nurseresidency/1175/thumbnail ...
Decker, Meghan, RN
core   +1 more source

On-demand therapies-emergency medication or daily routine? [PDF]

J Neural Transm (Vienna)
Weise D, Gandor F.
europepmc   +1 more source