Results 131 to 140 of about 69,629 (300)
Movement Disorders Clinical Practice, EarlyView.ABSTRACT Background Management of deep brain stimulation (DBS) in late‐stage Parkinson's disease (LSPD) remains challenging, particularly when deciding whether to continue or discontinue stimulation, and evidence on risk–benefit considerations is limited. Objectives To identify key factors to improve decision‐making in DBS management for LSPD patients.
Pietro Antenucci +9 more
wiley +1 more source
Levodopa versus levodopa sparing in early parkinson’s disease: can we meet halfway?
Revista de Investigación ClínicaMonotherapy is the recommended initial treatment for early Parkinson’s disease. The pharmacological options for initial treatment include dopaminergic agonists, monoamine oxidase B inhibitors, and levodopa formulations.
Mayela Rodríguez-Violante +7 more
doaj +1 more source
Cortico-striatal gamma oscillations are modulated by dopamine D3 receptors in dyskinetic rats
Neural Regeneration ResearchLong-term levodopa administration can lead to the development of levodopa-induced dyskinesia. Gamma oscillations are a widely recognized hallmark of abnormal neural electrical activity in levodopa-induced dyskinesia.
Pengfei Wang +8 more
doaj +1 more source
Differential neuropsychological profiles in Parkinsonian patients with or without vascular lesions. [PDF]
, 2010 The purpose of this study is to compare the neuropsychological profile of patients affected by parkinsonism and vascular lesions to that in patients with PD alone (PD) and to evaluate whether the brain vascular lesion load is associated with ...
Antonini A +6 more
core
Subthalamic Nucleus Deep Brain Stimulation Improves Kinetic Tremor in Parkinson's Disease
Movement Disorders Clinical Practice, EarlyView.Abstract Background Although resting tremor is a characteristic feature of Parkinson's disease (PD), many patients also suffer from action tremor. Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is effective in reducing motor symptoms. However, it is unclear to what extent STN‐DBS improves action tremor in PD, particularly kinetic tremor.
Iwan Grooters +8 more
wiley +1 more source
Cortical nicotinic receptors in Alzheimer's disease and Parkinson's disease [PDF]
, 1991 Lange, Klaus W. +4 more
core +1 more source
Movement Disorders Clinical Practice, EarlyView.Abstract Background Visuospatial deficits in Parkinson's disease (PD) often precede dementia and complicate daily functioning. Alzheimer's disease (AD) pathology and α‐synuclein aggregation frequently co‐occur in PD, but their combined impact on cognition is unclear.
David Ledingham +8 more
wiley +1 more source
Deep Brain Stimulation and Pregnancy: A Case Report and Literature Review
Movement Disorders Clinical Practice, EarlyView.
Verónica Cabreira, Maria José Rosas
wiley +1 more source
Reduced Dopamine Transporter Uptake in Dentatorubral‐Pallidoluysian Atrophy
Movement Disorders Clinical Practice, EarlyView.
Kei Okuba +3 more
wiley +1 more source
Hypotensive Episodes Precede Cognitive Fluctuations in Parkinson's Disease Dementia
Movement Disorders Clinical Practice, EarlyView.Abstract Background Cognitive fluctuations (CFs) are a disabling feature in Parkinson's disease dementia (PDD) and contribute to caregiver burden. The relationship between CFs and neurogenic orthostatic hypotension (nOH), a common autonomic complication in PDD, has not been adequately examined.
Jorge Patino +6 more
wiley +1 more source