Results 221 to 230 of about 69,036 (281)

Astrocytes as central integrators of neural circuit function: Mechanisms and dysregulation in neuropsychiatric disorders

Clinical and Translational Discovery, Volume 6, Issue 2, April 2026.
1. Astrocytes are central integrators of neural circuit function through tripartite synapse modulation and neurovascular coupling. 2. Dysregulation of glutamate/GABA homeostasis and neuroinflammation represents shared mechanisms across diverse neuropsychiatric disorders. 3.
Xinyu Liu, Xinyue Zhou, Ruotong Meng, Yanxi Chen, You Chen, Blake Highet, Maurice Curtis, Bernhard Hirt, Shunying Yu, Jin Zhou, Linya You   +10 more
wiley   +1 more source

Levodopa/carbidopa/entacapone versus levodopa/benserazide plus pramipexole in Chinese patients with Parkinson's disease experiencing wearing off. [PDF]

Front Neurol
Yu C, Liu W, Gong A, Ye M, Huang H, Zhao Y, Liu C, Guo Y, Chen J, Zhang X, Chen X, Shen L, Li D.   +12 more
europepmc   +1 more source

Patient Characteristics and Outcomes of Endoscopically Placed Dedicated Transgastric Jejunal Tubes Compared to Percutaneous Endoscopic Gastrostomy With Jejunal Extension Tubes

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives Patients requiring long‐term enteral nutrition or continuous infusion of carbidopa/levodopa can benefit from jejunostomy tube placement. Recently, directly placed percutaneous transgastric jejunal tubes (TGJs) have been used instead of gastrostomy tubes with jejunal extensions (PEG‐Js) for enteral access.
Laura D. Kek, David H. Bruining, Navtej S. Buttar, Hadi Abou Zeid, Andrew C. Storm, William S. Harmsen, Louis M. Wong Kee Song, Nayantara Coelho‐Prabhu   +7 more
wiley   +1 more source

Sexual Dysfunction in Individuals with Early-Onset Parkinson's Disease in Ethiopia: Gender Differences and Correlation with Anti-Parkinson's Medication, Stigma, and Distress. [PDF]

Healthcare (Basel)
Alenko A, Sudhakar M, Chelkeba L, Keygnaert I.   +3 more
europepmc   +1 more source

Oropharyngeal Dysphagia in Parkinson's Disease: An Analysis of Prevalence, Swallow Therapy Utilization, and Complication Rates

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 2, April 2026.
ABSTRACT Objective Oropharyngeal dysphagia (OD) is a common and challenging manifestation of Parkinson's disease (PD), associated with risks of malnutrition, aspiration, and reduced quality of life. This study investigates interventions, complications, and factors associated with swallow therapy utilization in a national cohort of individuals with PD ...
Vicki Liu, Nader Wehbi, Priyanka Sai, Kathleen Cazzato, Helena Yip   +4 more
wiley   +1 more source

Microbial Metabolism of Levodopa as an Adjunct Therapeutic Target in Parkinson's Disease. [PDF]

Antioxidants (Basel)
Feix JB, Cheng G, Hardy M, Kalyanaraman B.   +3 more
europepmc   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, Volume 101, Issue 2, Page 751-803, April 2026.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

Letter to the Editor Regarding 'Levodopa Intestinal Gel Infusion Therapies in Advanced Parkinson's Disease: A Swedish Study on Real-World Use and Costs'. [PDF]

Neurol Ther
Smith N.
europepmc   +1 more source

The Effect of Deep Brain Stimulation on Sleep and Cognition in Patients With Parkinson's Disease

Journal of Sleep Research, Volume 35, Issue 2, April 2026.
ABSTRACT Sleep–wake disturbances and cognitive decline are among the most common nonmotor symptoms of Parkinson's disease (PD). Deep brain stimulation (DBS) can successfully alleviate motor symptoms. However, the impact on sleep–wake disturbances and cognitive decline, and their interaction, is yet unclear.
Monique E. H. Valk‐Geuke, Gert J. Geurtsen, Rob M. A. de Bie, Rick Schuurman, Martijn Beudel, Esmée Verwijk   +5 more
wiley   +1 more source

Response to "Letter to the Editor" Regarding Odin P, et al. 2025 'Levodopa Intestinal Gel Infusion Therapies in Advanced Parkinson's Disease: A Swedish Study on Real-World Use and Costs'. [PDF]

Neurol Ther
Taerud C.
europepmc   +1 more source