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Cardiovascular effects of levodopa
Clinical Pharmacology & Therapeutics, 1971The patient with Parkinson's disease under treatment with levodopa may be subject to potentially hazardous cardiovascular effects. The most serious side effect of levodopa in patients is ventricular arrhythmia which is unlikely to occur in a subject with normal heart but a risk in patients with myocardial irritability or ischemia.
L I, Goldberg, T L, Whitsett
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The American Journal of Nursing, 1974
chronic care facility with no hope of improvement. Parkinsonism is a fairly common, disabling, movement disorder caused by dysfunction of the extrapyramidal system. There are 90 to 110 cases per 100,000 people and an annual incidence of 20 cases per 100,000 people in the United States(1).
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chronic care facility with no hope of improvement. Parkinsonism is a fairly common, disabling, movement disorder caused by dysfunction of the extrapyramidal system. There are 90 to 110 cases per 100,000 people and an annual incidence of 20 cases per 100,000 people in the United States(1).
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Neurology, 1998
Whether a drug such as levodopa, which is prescribed for long periods, may be toxic is a legitimate and even indispensable question. The problem is no different from that posed by other drugs-such as calcium antagonists, antihypertensives, or hormones-normally prescribed for chronic diseases. What, however, is meant in this context by "toxic" (from the
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Whether a drug such as levodopa, which is prescribed for long periods, may be toxic is a legitimate and even indispensable question. The problem is no different from that posed by other drugs-such as calcium antagonists, antihypertensives, or hormones-normally prescribed for chronic diseases. What, however, is meant in this context by "toxic" (from the
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Annals of Internal Medicine, 1980
Excerpt To the editor: The letter of Lejonc and colleagues (1) in the November 1979 issue on a patient who developed flushing and palpitations and, later, elevated pulse rate and blood pressure as ...
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Excerpt To the editor: The letter of Lejonc and colleagues (1) in the November 1979 issue on a patient who developed flushing and palpitations and, later, elevated pulse rate and blood pressure as ...
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Determination of Purity of Levodopa and Levodopa Products by GLC
Journal of Pharmaceutical Sciences, 1974A simple GLC procedure for the detection and quanti-tation of possible impurities in levodopa raw material and commercial dosage forms is presented. The sample is reacted with N,O-bis(trimethylsilyl)acetamide in acetonitrile at ambient temperature for 30 min, and the silyl derivatives are separated on a methyl silicone column under isothermal ...
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