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Antibiotic resistance of Helicobacter pylori in the European part of the Russian Federation: first results [PDF]
Aim. Determine the primary antibiotic resistance of Helicobacter pylori (H. pylori) strains isolated from patients living in the European part of the Russian Federation. Materials and methods. As part of a clinical laboratory study, from 2015 to 2018,
I. V. Maev +15 more
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Synthesis a Number of Heterocyclic Compounds and some of chalcones Derived From Levofloxacin
The hydrazide (1) was used as synthone for the following Compound pyridazine-3,6-dione (2) by reaction of hydrazide (1) with maleic anhydride and Compound phthalazine-1,4-dione (3) by the reaction of hydrazide (1) with phthalic anhydride.
Ekram Abdullah Basheer +2 more
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Update on the second-line treatment of infection: a narrative review
A standard bismuth quadruple therapy, a fluoroquinolone-containing triple (or quadruple) therapy or a proton pump inhibitor (PPI)-amoxicillin high-dose dual therapy has been recommended as a second-line treatment for Helicobacter pylori infection by the ...
Chih-An Shih +5 more
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Numerical Mechanistic Modelling of Drug Release from Solvent-Removal Zein-Based In Situ Gel
The development of effective drug delivery systems remains a focus of extensive research to enhance therapeutic outcomes. Among these, in situ forming gels (ISG) have emerged as a promising avenue for controlled drug release. This research focuses on the
Setthapong Senarat +4 more
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Adsorption of Levofloxacin on Microplastics in Aqueous Solution [PDF]
Objectives Recently, microplastics (MPs) is observed at surface water in worldwide because of massive use of plastics. Since MPs have a large specific surface area, they could provide adsorption sites to water contaminants such as Levofloxacin (LVF). LVF
Jooyoung Lee, Jeong-Ann Park
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Current development of Helicobacter pylori eradication protocols
H. pylori is one of the most common commensal microorganisms in the human body, colonizing up to 60% of the inhabitants of all continents. Some strains of H.
A. O. Pozdeeva +4 more
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Photocatalytic materials and semiconductors of appropriate structural and morphological architectures as well as energy band gaps are materials needed for mitigating current environmental problems, as these materials have the ability to exploit the full ...
Shelja Sharma +7 more
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Neurotoxicity is a rare and intolerable adverse effect associated with levofloxacin therapy, whose diagnosis has mostly been reported based on medical history rather than quantitative measures in the blood.
Masashi Nishikubo +2 more
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The consequences of non-adherence to treatment (NAT) on antimicrobial efficacy may depend on drug forgiveness—a property that should account for pharmacokinetics (PK) and pharmacodynamics (PD) as well as interindividual variability.
Nerea Carral +5 more
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Rational search of a ligand for a specific receptor is a cornerstone of a typical drug discovery process. However, to make it more “rational” one would appreciate having detailed information on the functional groups involved in ligand-receptor ...
Igor D. Zlotnikov, Elena V. Kudryashova
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