Results 81 to 90 of about 6,081 (225)

Levosimendan does not reduce the mortality of critically ill adult patients with sepsis and septic shock: a meta-analysis

Chinese Medical Journal, 2019
. Background:. Previous studies on whether or not levosimendan improved the prognosis of patients with sepsis and septic shock have been inconsistent. We aimed to provide an updated analysis of the therapeutic value of levosimendan in adult patients with
Fang Feng, Yu Chen, Min Li, Jiao-Jiao Yuan, Xue-Ni Chang, Chen-Ming Dong, Li-Min Chen   +6 more
doaj   +1 more source

Furosemide‐hydration matching with RenalGuard® in decompensated heart failure: an alternative way to use diuretics and saline

ESC Heart Failure, Volume 12, Issue 4, Page 3200-3208, August 2025.
Massimo Mapelli, Filippo Maria Rubbo, Jeness Campodonico, Nicola Cosentino, Giancarlo Marenzi, Valentina Mantegazza, Filippo Trombara, Mateusz Sokolski, Piotr Ponikowski, Piergiuseppe Agostoni   +9 more
wiley   +1 more source

An In Vitro Investigation of the Antiproliferative and Antimetastatic Effects of Levosimendan: Potential Drug Repurposing for Cervical Cancer

Current Issues in Molecular Biology
Cervical cancer presents a significant challenge to the global health of women. Despite substantial advances in human papillomavirus (HPV)-related cervical cancer vaccines, non-HPV-related cervical cancer is still waiting novel therapeutic options.
Zsuzsanna Schelz, Hiba F. Muddather, Fatemeh Sheihaki Jaski, Noémi Bózsity, István Zupkó   +4 more
doaj   +1 more source

Levosimendan in sepsis [PDF]

Journal of Clinical Intensive Care and Medicine, 2020
Ugur Koca, Burcu Tanay Demirdöven
openaire   +2 more sources

The effect of the calcium sensitizer levosimendan on the performance and the response to pacing of stunned myocardium in anaesthetized pigs [PDF]

, 2000
H. Schad, W. Heimisch, Peter Tassani, Angelika Bernhard-Abt, Ursula Ettner, N. Mendler, R Lange   +6 more
openalex   +1 more source

Hyperglycemia raises the threshold of levosimendan- but not milrinone-induced postconditioning in rat hearts

Cardiovascular Diabetology, 2012
Background The authors examined whether milrinone and levosimendan could exert cardiac postconditioning effects in rats under normoglycemia and hyperglycemia, and whether the effects could be mediated by mitochondrial permeability transition pore (mPTP).
Matsumoto Shuhei, Cho Sungsam, Tosaka Shinya, Higashijima Ushio, Maekawa Takuji, Hara Tetsuya, Sumikawa Koji   +6 more
doaj   +1 more source

Levosimendan For Post-Partum Cardiomyopathy

Critical Care and Resuscitation, 2005
To describe the use of levosimendan, a novel inotropic agent, for the treatment of post-partum cardiomyopathy (PPCMO).The authors present the second recorded use of levosimendan for a woman with PPCMO.Levosimendan improved cardiac performance which was associated with symptomatic relief and echocardiographic improvement in ventricular function.
H D, Nguyen, B, McKeown
openaire   +2 more sources

Binding of Levosimendan, a Calcium Sensitizer, to Cardiac Troponin C [PDF]

, 2001
Tia Sorsa, Sami Heikkinen, M.Bret Abbott, Ekram Abusamhadneh, Tero Laakso, Carola Tilgmann, Ritva Serimaa, Arto Annila, Paul R. Rosevear, Torbjörn Drakenberg, Piero Pollesello, Ilkka Kilpeläinen   +11 more
openalex   +1 more source

Levosimendan in acute heart failure

Signa Vitae, 2008
Numerous adverse effects and an increased mortality are the reasons why many clinicians are often unsuccessful with the inotropic agents presently in use. New therapeutic agents have been developed in the last few years to assist the clinician in the stabilization, support and treatment of cardiovascular disease.One of the newest groups of inotropic ...
HUSEDZINOVIC, INO, MILANOVIC, RUDI, HUSEDZINOVIC, SANJA   +2 more
openaire   +4 more sources

Intravenous levosimendan treatment is cost‐effective compared with dobutamine in severe low‐output heart failure: an analysis based on the international LIDO trial [PDF]

, 2003
John G.F. Cleland, A. Takala, Marjo Apajasalo, Niklas Zethraeus, Gisela Kobelt   +4 more
openalex   +1 more source