Results 121 to 130 of about 41,299 (161)
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2003
Our understanding of the clinical and pathological features of dementia in late life is changing. Indeed, the way we conceptualize, investigate, and manage dementia has altered radically over recent times. An increasing public awareness, coupled with greater expectations, changing demography, and an ever more productive research alliance among ...
Robert Barber +2 more
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Our understanding of the clinical and pathological features of dementia in late life is changing. Indeed, the way we conceptualize, investigate, and manage dementia has altered radically over recent times. An increasing public awareness, coupled with greater expectations, changing demography, and an ever more productive research alliance among ...
Robert Barber +2 more
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Lewy Body Pathology in Alzheimer's Disease
Journal of Molecular Neuroscience, 2001Lewy bodies, the characteristic pathological lesion of substantia nigra neurons in Parkinson's disease (PD), are frequently observed to accompany the amyloid plaque and neurofibrillary tangle pathology of Alzheimer's disease (AD). However the typical anatomic distribution of Lewy bodies in AD is distinct from PD.
P T, Kotzbauer +2 more
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Dementia with Lewy bodies and Parkinson's disease
Parkinsonism & Related Disorders, 2004Lewy bodies (LB) in the central nervous system are associated with several different clinical syndromes including Parkinson's disease (PD) and dementia with Lewy bodies (DLB). Long term follow up of PD patients finds up to 78% eventually develop dementia, most of these patients exhibiting fluctuating cognition and visual hallucinations similar to DLB ...
I G, McKeith, U P, Mosimann
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Neuropathology of prodromal Lewy body disease
Movement Disorders, 2014ABSTRACTBackgroundCurrent evidence suggests that there is a prodromal stage in Parkinson disease characterized by a variety of nonmotor symptoms.Methods and ResultsA 69‐year‐old man presented to our sleep center with isolated rapid eye movement sleep behavior disorder.
Alex, Iranzo +6 more
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2019
Fritz Heinrich Lewy described the intracytoplasmic inclusions found in the neurons for the very first time. In 1919 these inclusions were termed as “LBs” by Tretiakoff. LBs were found in the brain of the patients suffering from Lewy body disease (LBD).
Vaibhav Walia, Munish Garg
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Fritz Heinrich Lewy described the intracytoplasmic inclusions found in the neurons for the very first time. In 1919 these inclusions were termed as “LBs” by Tretiakoff. LBs were found in the brain of the patients suffering from Lewy body disease (LBD).
Vaibhav Walia, Munish Garg
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Lewy Bodies in the Presence of Alzheimer's Disease
Archives of Neurology, 1979Large numbers of Lewy bodies in the substantia nigra were found in a case of Alzheimer's disease. Parkinsonian symptoms were not recognized. The patient appears to be an example of an association recognized by Woodard but not yet understood. The case is discussed in the context of reported relationships between Parkinson's disease or "Lewy body disease"
W I, Rosenblum, N R, Ghatak
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Current opinion in neurology and neurosurgery, 1993
Subsumed under the rubric of Lewy body disease are idiopathic Parkinson's disease (PD), pure diffuse Lewy body disease (DLBD), and, most commonly, combined brainstem and neocortical Lewy bodies with Alzheimer's disease (AD) pathology in a relatively early developmental stage.
L A, Hansen, D, Galasko
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Subsumed under the rubric of Lewy body disease are idiopathic Parkinson's disease (PD), pure diffuse Lewy body disease (DLBD), and, most commonly, combined brainstem and neocortical Lewy bodies with Alzheimer's disease (AD) pathology in a relatively early developmental stage.
L A, Hansen, D, Galasko
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The Lewy body variant of Alzheimer disease
1997The Lewy body variant of Alzheimer disease (LBV) occupies a messy middle ground between Alzheimer disease (AD) on the one hand, and pure Lewy body diseases (Parkinson's disease or diffuse Lewy body disease), on the other. In addition to brainstem and neocortical Lewy bodies, LBV brains have enough neocortical neuritic plaques to meet diagnostic ...
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Diffuse lewy body disease in Japan
Journal of Neurology, 1990Thirty-seven Japanese autopsy cases with diffuse Lewy body disease (DLBD) were reviewed from a clinicopathological viewpoint. Based on the neuropathological finding of whether or not many concomitant senile plaques (SPs) and/or neurofibrillary tangles (NFTs) are present. DLBD is divided into two forms: a common form and a pure form.
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