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Leydig Cell and Spermatogenesis
2021Leydig cells of the testis have the capacity to synthesize androgen (mainly testosterone) from cholesterol. Adult Leydig cells are the cell type for the synthesis of testosterone, which is critical for spermatogenesis. At least four steroidogenic enzymes take part in testosterone synthesis: cytochrome P450 cholesterol side chain cleavage enzyme, 3β ...
Ren-Shan, Ge, Xiaoheng, Li, Yiyan, Wang
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The cross talk of adrenal and Leydig cell steroids in Leydig cells
The Journal of Steroid Biochemistry and Molecular Biology, 2019Glucocorticoid is secreted by adrenal cortex, which binds to intracellular glucocorticoid and mineralocorticoid receptors to regulate steroidogenesis-related gene expression and testosterone production in Leydig cells. Glucocorticoid receptor activity shows inhibitory action on Leydig cell steroidogenesis, while mineralocorticoid receptor activity ...
Yiyan, Wang +5 more
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INSL3 Expression in Leydig Cell Hyperplasia and Leydig Cell Tumors
Applied Immunohistochemistry & Molecular Morphology, 2019Insulin-like 3 (INSL3) is a hormone produced by Leydig cells (LCs) and leads to physiological testicular descent during embryonic development. We investigated the expression of INSL3 by immunohistochemistry in normal LCs, in Leydig cell tumor (LCT) (n=17 including 15 testes and 2 ovaries) and in Leydig cell hyperplasia (LCH) (n=10).
Nelli S, Lakis +5 more
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2018
Leydig cells (LC) are found in the testicular interstitial tissue surrounding the seminiferous tubules. Their primary function is to produce testosterone (T), which is crucial for maintaining spermatogenesis and supporting extra-testicular androgenic, psychological, and anabolic functions.
Huhtaniemi, I., Teerds, K.J.
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Leydig cells (LC) are found in the testicular interstitial tissue surrounding the seminiferous tubules. Their primary function is to produce testosterone (T), which is crucial for maintaining spermatogenesis and supporting extra-testicular androgenic, psychological, and anabolic functions.
Huhtaniemi, I., Teerds, K.J.
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1983
The role of the testis in the development of masculine features has been known for literally thousands of years. It is, however, only within the past 150 years that we have begun to understand how the testes have these effects. The location and appearances of the cells that now bear his name were first described by Von Leydig in 1857.
Y, Hodgson, B, Hudson
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The role of the testis in the development of masculine features has been known for literally thousands of years. It is, however, only within the past 150 years that we have begun to understand how the testes have these effects. The location and appearances of the cells that now bear his name were first described by Von Leydig in 1857.
Y, Hodgson, B, Hudson
openaire +2 more sources