Results 211 to 220 of about 4,930,458 (259)
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Archives of Andrology, 1986
The ultrastructure of Leydig cell hyperplasia is described. The hyperplastic Leydig cells differ morphologically from normal Leydig cells as well as from Leydig tumor cells. They have less smooth endoplasmic reticulum and less lipofuscin pigment in their cytoplasm, and the nuclear membrane shows more irregular indentations than normal Leydig cells.
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The ultrastructure of Leydig cell hyperplasia is described. The hyperplastic Leydig cells differ morphologically from normal Leydig cells as well as from Leydig tumor cells. They have less smooth endoplasmic reticulum and less lipofuscin pigment in their cytoplasm, and the nuclear membrane shows more irregular indentations than normal Leydig cells.
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Physiology and Pathology of the Leydig Cell
New England Journal of Medicine, 1980LEYDIG cells, the interstitial cells of the testes, lie between the seminiferous tubules and produce androgenic steroids. The secretion of testosterone in men has been thought to be regulated by a feedback system in which luteinizing hormone from the anterior pituitary stimulates the conversion of cholesterol to testosterone.
Howard L. Bleich +2 more
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Control of steroidogenesis in Leydig cells
The Journal of Steroid Biochemistry and Molecular Biology, 1992Luteinizing hormone (LH) interacts with its plasma membrane receptor to stimulate steroidogenesis not only via cyclic AMP but also other pathways which include arachidonic acid and leukotrienes and regulation of chloride and calcium channels. The same stimulatory pathways may lead to desensitization and down-regulation of the LH receptor and ...
B A, Cooke +4 more
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Leydig Cell in Idiopathic Varicocele
European Urology, 1990In a group of 31 patients with idiopathic varicocele (IV), testicular biopsy showed a decreased tubular diameter, hyperplasia in the number of Leydig's cells (LC; many with cytoplasmic vacuolization and atrophy) and a decrease in the number of positive LC in testicular tissue sections stained with the testosterone peroxidase-antiperoxidase method ...
J J, Sirvent +5 more
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Congenital Leydig cell hyperplasia
Histopathology, 1988The testes and epididymes collected at autopsy from 21 newborns showed apparent Leydig cell hyperplasia which was studied by light and electron microscopy. Twelve newborns were the sons of diabetic mothers, two had undergone rhesus isoimmunization, two were twins of a non‐diabetic mother, three had Beckwitz‐Widemann's syndrome, and two had ...
M, Nistal +2 more
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Leydig-cell tumour of the testis
International Urology and Nephrology, 1980Leydig cell tumor of the testis is an uncommon occurrence. A case is reported here which had two interesting features. One was extensive calcification and the other an abundant lipid deposition within the tumour cells. The pathogenesis of calcification is discussed.
R, Malik +4 more
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Urology, 1979
In adult patients with Leydig cell tumor of the testis, endocrinologic signs occur in 30 per cent of the cases and often precede the onset of a palpable testicular mass. Gynecomastia is the most common endocrinologic manifestation and probably is due to increased estrogen secretion by the Leydig cells.
A A, Caldamone +3 more
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In adult patients with Leydig cell tumor of the testis, endocrinologic signs occur in 30 per cent of the cases and often precede the onset of a palpable testicular mass. Gynecomastia is the most common endocrinologic manifestation and probably is due to increased estrogen secretion by the Leydig cells.
A A, Caldamone +3 more
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Differentiation of adult Leydig cells
The Journal of Steroid Biochemistry and Molecular Biology, 1995Adult Leydig cells originate within the testis postnatally. Their formation is a continuous process involving gradual transformation of progenitors into the mature cell type. Despite the gradual nature of these changes, studies of proliferation, differentiation and steroidogenic function in the rat Leydig cell led to the recognition of three distinct ...
L, Benton, L X, Shan, M P, Hardy
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Archives of Gynecology and Obstetrics, 2001
Sertoli-Leydig cell tumors belong to the group of sex-cord stromal tumors of the ovary. They account for less than 0,5% of all ovarian neoplasms. The majority of these tumors are benign, and almost all are localised unilaterally. Herewith, we describe an ovarian Sertoli-Leydig cell tumor in an 11-year-old girl.
T, Lantzsch +5 more
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Sertoli-Leydig cell tumors belong to the group of sex-cord stromal tumors of the ovary. They account for less than 0,5% of all ovarian neoplasms. The majority of these tumors are benign, and almost all are localised unilaterally. Herewith, we describe an ovarian Sertoli-Leydig cell tumor in an 11-year-old girl.
T, Lantzsch +5 more
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The ultrastructure of testicular tumours in the dog: II. Leydig cells and Leydig cell tumours
Journal of Comparative Pathology, 1978Abstract The ultrastructural appearance of testicular Leydig cells in healthy dogs as well as canine Leydig cell tumours is described. The cells of most Leydig cell tumours (10 out of 13) showed the typical characteristics of normal Leydig cells: abundant smooth endoplasmic reticulum, mitochondria with tubular inner structures and numerous small and ...
D, von Bomhard +2 more
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