Results 51 to 60 of about 144,273 (312)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Multiple roles for the cytoplasmic C-terminal domains of the yeast cell surface receptors Rgt2 and Snf3 in glucose sensing and signaling

Scientific Reports
The plasma membrane proteins Rgt2 and Snf3 are glucose sensing receptors (GSRs) that generate an intracellular signal for the induction of gene expression in response to high and low extracellular glucose concentrations, respectively. The GSRs consist of
Jeong-Ho Kim, Levi Mailloux, Daniel Bloor, Haeun Tae, Han Nguyen, Morgan McDowell, Jaqueline Padilla, Anna DeWaard   +7 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Personal Papers (MS 80-0002)

, 1948
Letter from Liberty Music Shops, Inc. to D. W.
Liberty Music Shops, Incorporated, Farber, Ellis R.   +1 more
core  

Regional analysis of telavancin and comparator antimicrobial activity against multidrug-resistant Staphylococcus aureus collected in the USA 2014–2016

Journal of Global Antimicrobial Resistance, 2020
Objectives: The in vitro antimicrobial activities of telavancin and comparator antimicrobials were evaluated against recent Staphylococcus aureus (S. aureus) clinical isolates collected in the United States of America (USA). Methods: A total of 15 882 S.
Leonard R. Duncan, Caitlin J. Smith, Robert K. Flamm, Rodrigo E. Mendes   +3 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Oral History Interview with Arthur R. Liberty, August 25, 2005

, 2005
The National Museum of the Pacific War presents an oral interview with Arthur Liberty. Born in Vermont, Liberty quit high school in 1942 to join the Marine Corps. He took boot training at Parris Island for nine weeks before going to Camp Lejeune where he
Liberty, Arthur R.
core  

On submultiplicative constants of an algebra

Journal of Inequalities and Applications, 2019
If A $\mathcal{A}$ is a finite-dimensional commutative associative real algebra with norm ∥⋅∥ $\| \cdot\|$ then we say that the rth submultiplicative constant of A $\mathcal{A}$ is the smallest constant mr(A) $m_{r}(\mathcal{A})$ for which ∥x1x2⋯xr∥≤mr(A)
James S. Cook, Khang V. Nguyen
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Liberty Hall sign construction

, 1971
Black and white photograph of construction of the Liberty Hall signThe Houston music venue, Liberty Hall, was open between 1971 and ...
Liberty Hall
core   +2 more sources