Results 61 to 70 of about 209,313 (263)

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Liberty Hall sign construction

, 1971
Black and white photograph of construction of the Liberty Hall signThe Houston music venue, Liberty Hall, was open between 1971 and ...
Liberty Hall
core   +2 more sources

Community living causes changes in metabolic behavior and is permitted by specific growth conditions in two bacterial co-culture systems

Journal of Bacteriology
Although bacteria exist in complex microbial communities in the environment, their features and behavior are most often studied in monoculture. While environmental enrichments or complex co-cultures with tens or hundreds of members might more accurately ...
Elizabeth Ellis, Sam Fulte, Skyler Boylan, Alaina Flory, Katherine Paine, Sophia Lopez, Grace Allen, Kanwar Warya, Javier Ortiz-Merino, Sadie Blacketer, Samantha Thompson, Sierra Sanchez, Kayla Burdette, Audrey Duchscherer, Nick Pinkham, Joseph D. Shih, Lilah Rahn-Lee   +16 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

They made Leicester's Statue of Liberty

, 1998
Article from pp.10 of the Leicester Mercury, Monday March 23rd 1998 about the construction of the Statue of Liberty statue that was to be on top of the Liberty Works, Eastern Boulevard. Bill Briggs had mentored David Simpson when he joined the firm.

core  

Liberty Hombe Honors Portfolio [PDF]

, 2022
Liberty Hombe\u27s honors portfolio captured in May ...
Hombe, Liberty
core  

Ready to take the Liberty

Newspaper article from pp.15 of the Leicester Mail about the former shoe factory the Liberty Building, Eastern Boulevard being put up for sale. Possible suggestions for it's use are suggested.

core   +1 more source