Results 51 to 60 of about 1,508,332 (327)
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
JLIS.it, 2013 The amount of data available in the linked data cloud has grown enormously in the last years in several domains, including cultural heritage and digital humanities.
Michele Barbera
doaj +1 more source
Linked Data in Library Workflows
NASIG ProceedingsAs the library community continues to explore linked data for cataloging and data management, there are a variety of new opportunities as well as challenges to ensure that data is interoperable and manageable across bibliographic datasets. Data model interoperability is critical to ensure we can continue to manage bibliographic materials at scale ...
Anne Washington, Jeff Mixter
openaire +1 more source
datos.bne.es: A library linked dataset [PDF]
, 2012 We describe the datos.bne.es library dataset. The dataset makes available the authority and bibliography catalogue from the Biblioteca Nacional de España (BNE, National Library of Spain) as Linked Data.
Gómez-Pérez, A. +2 more
core +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
JLIS.it, 2013 "Legal interoperability" could be defined as the possibility of legally mixing data coming from different sources (including governmental data, data generated by online communities and data held by private parties).
Federico Morando
doaj +1 more source
Linked Open Data for Libraries
, 2020 Presentation given at NVB 2011 Conference, The Netherlands.
openaire +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
New Library World, 2012 PurposeThe purpose of this paper is to provide recommendations for making a conceptual shift from current document‐centric to data‐centric metadata. The importance of adjusting current library models such as Resource Description and Access (RDA) and Functional Requirements for Bibliographic Records (FRBR) to models based on Linked Data principles is ...
Alemu, Getaneh +3 more
openaire +3 more sources
Highlights of library data models in the era of Linked Open Data [PDF]
, 2013 Semantic Web technologies and Linked data form a new reference framework for libraries. The library community aims to integrate its data with the Semantic Web and as a result new library data models have been developed.
Papatheodorou, Christos +2 more
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