Results 71 to 80 of about 1,508,332 (327)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Le iniziative del FRBR Review Group e il mondo Linked data
JLIS.it, 2013 The FRBR Review Group has the mandate to review and maintain IFLA's family of conceptual models and to develop guidelines and interpretive documents to assist in the application of the models.
Pat Riva
doaj +1 more source
Report of the Stanford Linked Data Workshop
, 2011 The Stanford University Libraries and Academic Information Resources (SULAIR) with the Council on Library and Information Resources (CLIR) conducted at week-long workshop on the prospects for a large scale, multi-national, multi-institutional prototype ...
Calter, Mimi +3 more
core
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Clusters of microRNAs emerge by new hairpins in existing transcripts [PDF]
, 2013 Genetic linkage may result in the expression of multiple products from a polycistronic transcript, under the control of a single promoter. In animals, protein-coding polycistronic transcripts are rare.
Alberts +66 more
core +2 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
LTS and Linked Data: a position paper [PDF]
, 2015 "LTS and Linked Data: a position paper" outlines motivations for adopting linked data techniques for describing and managing our collections, and seeks to articulate a specific role for Library Technical Services (LTS) within this ...
Chew, Chiat Naun +2 more
core
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Linking Library Metadata to the Web: the German Experiences
JLIS.it, 2013 One of the major challenges of libraries today is to make metadata available for the usage and re-usage by researchers and the scientific community. Therefore it is necessary to open the cataloguing systems for non-restricted and completely free access.
Gabriele Meßmer
doaj +6 more sources
Towards a Resource-Centric Data Network for Astronomy
, 2010 Over the past decade, astronomers have been using an increasingly larger number of web-based applications and archives to conduct their research. However, despite the early success in creating links across projects and data centers, the promise of a ...
Accomazzi, Alberto +2 more
core +1 more source