Results 1 to 10 of about 2,433,325 (381)
NKG2D and its ligands: one for all, all for one [PDF]
The activating receptor NKG2D is peculiar in its capability to bind to numerous and highly diversified MHC class I-like self-molecules. These ligands are poorly expressed on normal cells but can be induced on damaged, transformed or infected cells, with ...
Cerboni, Cristina +7 more
core +7 more sources
Antimicrobial Activity of Mononuclear and Bionuclear Nitrite Complexes of Platinum (II) and Platinum (IV) [PDF]
Introduction. Pathogens keep evolving and develop resistance to antimicrobial drugs. As a result, science is constantly searching for new antimicrobial agents.
Salishcheva Olesya V. +2 more
doaj +1 more source
Development of Radiotracers for Imaging of the PD-1/PD-L1 Axis
Immune checkpoint inhibitor (ICI) therapy has emerged as a major treatment option for a variety of cancers. Among the immune checkpoints addressed, the programmed death receptor 1 (PD-1) and its ligand PD-L1 are the key targets for an ICI.
Fabian Krutzek +2 more
doaj +1 more source
Glycols in the Synthesis of Zinc-Anilato Coordination Polymers
We report the synthesis, structural investigation, and thermal behavior for three zinc-based 1D-coordination polymers with 3,6-di-tert-butyl-2,5-dihydroxy-p-benzoquinone, which were synthesized in the presence of different glycols.
Olesya Y. Trofimova +5 more
doaj +1 more source
Charge Transfer Chromophores Derived from 3d-Row Transition Metal Complexes
A series of new charge transfer (CT) chromophores of “α-diimine-MII-catecholate” type (where M is 3d-row transition metals—Cu, Ni, Co) were derived from 4,4′-di-tert-butyl-2,2′-bipyridyl and 3,6-di-tert-butyl-o-benzoquinone (3,6-DTBQ) in accordance with ...
Kira I. Pashanova +7 more
doaj +1 more source
Two heteroleptic NiII complexes combined the redox-active catecholate and 2,2′- bipyridine ligand platforms were synthesized to observe a photoinduced intramolecular ligand-to-ligand charge transfer (LL’CT, HOMOcatecholate → LUMOα-diimine).
Kira I. Pashanova +4 more
doaj +1 more source
A dense and diverse array of glycans on glycoproteins and glycolipids decorate all cell surfaces. In vertebrates, many of these carry sialic acid, in a variety of linkages and glycan contexts, as their outermost sugar moiety. Among their functions, glycans engage complementary glycan binding proteins (lectins) to regulate cell physiology.
Anabel Gonzalez-Gil, Ronald L. Schnaar
openaire +3 more sources
Small interfering RNA (siRNA)-mediated mRNA degradation approach have imparted its eminence against several difficult-to-treat genetic disorders and other allied diseases.
Rushikesh Fopase +6 more
doaj +1 more source
Estimating tissue-specific peptide abundance from public RNA-Seq data
Several novel MHC class I epitope prediction tools additionally incorporate the abundance levels of the peptides’ source antigens and have shown improved performance for predicting immunogenicity.
Angela Frentzen +5 more
doaj +1 more source
Objective To investigate the anti⁃tumoral effect of ACT001, a novel antitumor compound, on the nuclear factor⁃κB (NF⁃κB) pathway and programmed cell death protein ligand 1 (PDL1) expression in U87 glioblastoma cell line.
ZHANG Jin⁃hao +9 more
doaj +1 more source

