Results 1 to 10 of about 2,296,826 (424)
A novel methodology on distributed representations of proteins using their interacting ligands [PDF]
Bioinformatics 2018, 2018 The effective representation of proteins is a crucial task that directly affects the performance of many bioinformatics problems. Related proteins usually bind to similar ligands. Chemical characteristics of ligands are known to capture the functional and mechanistic properties of proteins suggesting that a ligand based approach can be utilized in ...
Ozkirimli, Elif +2 more
arxiv +3 more sources
NKG2D and its ligands: one for all, all for one [PDF]
Frontiers in Immunology, 2018 The activating receptor NKG2D is peculiar in its capability to bind to numerous and highly diversified MHC class I-like self-molecules. These ligands are poorly expressed on normal cells but can be induced on damaged, transformed or infected cells, with ...
Cerboni, Cristina +7 more
core +3 more sources
The Role of Ligands in the Chemical Synthesis and Applications of Inorganic Nanoparticles
Chemical Reviews, 2019 The design of nanoparticles is critical for their efficient use in many applications ranging from biomedicine to sensing and energy. While shape and size are responsible for the properties of the inorganic nanoparticle core, the choice of ligands is of ...
Amelie Heuer-jungemann +2 more
exaly +2 more sources
A comprehensive evaluation of the activity and selectivity profile of ligands for RGD-binding integrins [PDF]
Scientific Reports, 2017 Integrins, a diverse class of heterodimeric cell surface receptors, are key regulators of cell structure and behaviour, affecting cell morphology, proliferation, survival and differentiation.
Cavalcanti-Adam, Elisabetta Ada +12 more
core +3 more sources
Facetted patchy particles through entropy-driven patterning of mixed ligand SAMS [PDF]
, 2011 We present a microscopic theory that describes the ordering of two distinct ligands on the surface of a faceted nanoparticle. The theory predicts that when one type of ligand is significantly bulkier than all others, the larger ligands preferentially align themselves along the edges and vertices of the nanoparticle.
Aaron Santos +62 more
arxiv +3 more sources
Cells, 2021 A dense and diverse array of glycans on glycoproteins and glycolipids decorate all cell surfaces. In vertebrates, many of these carry sialic acid, in a variety of linkages and glycan contexts, as their outermost sugar moiety. Among their functions, glycans engage complementary glycan binding proteins (lectins) to regulate cell physiology.
Anabel Gonzalez-Gil, Ronald L. Schnaar
openaire +3 more sources
Development of Radiotracers for Imaging of the PD-1/PD-L1 Axis
Pharmaceuticals, 2022 Immune checkpoint inhibitor (ICI) therapy has emerged as a major treatment option for a variety of cancers. Among the immune checkpoints addressed, the programmed death receptor 1 (PD-1) and its ligand PD-L1 are the key targets for an ICI.
Fabian Krutzek +2 more
doaj +1 more source
Glycols in the Synthesis of Zinc-Anilato Coordination Polymers
Crystals, 2022 We report the synthesis, structural investigation, and thermal behavior for three zinc-based 1D-coordination polymers with 3,6-di-tert-butyl-2,5-dihydroxy-p-benzoquinone, which were synthesized in the presence of different glycols.
Olesya Y. Trofimova +5 more
doaj +1 more source
Charge Transfer Chromophores Derived from 3d-Row Transition Metal Complexes
Molecules, 2022 A series of new charge transfer (CT) chromophores of “α-diimine-MII-catecholate” type (where M is 3d-row transition metals—Cu, Ni, Co) were derived from 4,4′-di-tert-butyl-2,2′-bipyridyl and 3,6-di-tert-butyl-o-benzoquinone (3,6-DTBQ) in accordance with ...
Kira I. Pashanova +7 more
doaj +1 more source
Molecules, 2021 Two heteroleptic NiII complexes combined the redox-active catecholate and 2,2′- bipyridine ligand platforms were synthesized to observe a photoinduced intramolecular ligand-to-ligand charge transfer (LL’CT, HOMOcatecholate → LUMOα-diimine).
Kira I. Pashanova +4 more
doaj +1 more source