Results 1 to 10 of about 2,182,583 (375)

NKG2D and its ligands: one for all, all for one [PDF]

open access: yesFrontiers in Immunology, 2018
The activating receptor NKG2D is peculiar in its capability to bind to numerous and highly diversified MHC class I-like self-molecules. These ligands are poorly expressed on normal cells but can be induced on damaged, transformed or infected cells, with ...
Cerboni, Cristina   +7 more
core   +3 more sources

The Role of Ligands in the Chemical Synthesis and Applications of Inorganic Nanoparticles

open access: yesChemical Reviews, 2019
The design of nanoparticles is critical for their efficient use in many applications ranging from biomedicine to sensing and energy. While shape and size are responsible for the properties of the inorganic nanoparticle core, the choice of ligands is of ...
Amelie Heuer-jungemann   +2 more
exaly   +2 more sources

A comprehensive evaluation of the activity and selectivity profile of ligands for RGD-binding integrins [PDF]

open access: yesScientific Reports, 2017
Integrins, a diverse class of heterodimeric cell surface receptors, are key regulators of cell structure and behaviour, affecting cell morphology, proliferation, survival and differentiation.
Cavalcanti-Adam, Elisabetta Ada   +12 more
core   +3 more sources

Facetted patchy particles through entropy-driven patterning of mixed ligand SAMS [PDF]

open access: yes, 2011
We present a microscopic theory that describes the ordering of two distinct ligands on the surface of a faceted nanoparticle. The theory predicts that when one type of ligand is significantly bulkier than all others, the larger ligands preferentially align themselves along the edges and vertices of the nanoparticle.
Aaron Santos   +62 more
arxiv   +3 more sources

Development of Radiotracers for Imaging of the PD-1/PD-L1 Axis

open access: yesPharmaceuticals, 2022
Immune checkpoint inhibitor (ICI) therapy has emerged as a major treatment option for a variety of cancers. Among the immune checkpoints addressed, the programmed death receptor 1 (PD-1) and its ligand PD-L1 are the key targets for an ICI.
Fabian Krutzek   +2 more
doaj   +1 more source

Glycols in the Synthesis of Zinc-Anilato Coordination Polymers

open access: yesCrystals, 2022
We report the synthesis, structural investigation, and thermal behavior for three zinc-based 1D-coordination polymers with 3,6-di-tert-butyl-2,5-dihydroxy-p-benzoquinone, which were synthesized in the presence of different glycols.
Olesya Y. Trofimova   +5 more
doaj   +1 more source

Charge Transfer Chromophores Derived from 3d-Row Transition Metal Complexes

open access: yesMolecules, 2022
A series of new charge transfer (CT) chromophores of “α-diimine-MII-catecholate” type (where M is 3d-row transition metals—Cu, Ni, Co) were derived from 4,4′-di-tert-butyl-2,2′-bipyridyl and 3,6-di-tert-butyl-o-benzoquinone (3,6-DTBQ) in accordance with ...
Kira I. Pashanova   +7 more
doaj   +1 more source

Square-Planar Heteroleptic Complexes of α-Diimine-NiII-Catecholate Type: Intramolecular Ligand-to-Ligand Charge Transfer

open access: yesMolecules, 2021
Two heteroleptic NiII complexes combined the redox-active catecholate and 2,2′- bipyridine ligand platforms were synthesized to observe a photoinduced intramolecular ligand-to-ligand charge transfer (LL’CT, HOMOcatecholate → LUMOα-diimine).
Kira I. Pashanova   +4 more
doaj   +1 more source

Spontaneous Patterning of Binary Ligand Mixtures on CdSe Nanocrystals: from Random to Janus Packing [PDF]

open access: yesACS Nano, (2023) 17(6) 5852-5860, 2023
Binary compositions of surface ligands are known to improve the colloidal stability and fluorescence quantum yield of nanocrystals (NCs), due to ligand-ligand interactions and surface organization. Herein, we follow the thermodynamics of a ligand exchange reaction of CdSe NCs with alkylthiols mixtures.
arxiv   +1 more source

Ligand-induced protein dynamics differences correlate with protein-ligand binding affinities: An unsupervised deep learning approach [PDF]

open access: yesCommun. Biol. 5, 481 (2022), 2021
Prediction of protein-ligand binding affinity is a major goal in drug discovery. Generally, free energy gap is calculated between two states (e.g., ligand binding and unbinding). The energy gap implicitly includes the effects of changes in protein dynamics induced by the binding ligand.
arxiv   +1 more source

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