Results 191 to 200 of about 2,296,826 (424)
Studies of Chelates with Heterocyclic Ligands. III. Coordination Compounds of Transition Metals with 5-Aminoquinoxaline. [PDF]
, 1967 Otto Dahl +8 more
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Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source
The Nature of the Metal-Ligand Bonds in Hexahalostannates(IV) and Ammonium Hexachloroplumbate(IV) Studied by the Pure Quadrupole Resonance of Halogens [PDF]
, 1963 Daiyû Nakamura
openalex +1 more source
Mapping Hsp104 interactions using cross‐linking mass spectrometry
FEBS Open Bio, EarlyView.This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal +3 more
wiley +1 more source
The Stability of Fused Rings in Metal Chelates. IV. Preparation and Relative Stability of Copper(II) Complexes with Tetradentate Schiff Base Ligands [PDF]
, 1969 Yasuo Nakao +2 more
openalex +1 more source
FEBS Open Bio, EarlyView.The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli +15 more
wiley +1 more source
FEBS Open Bio, EarlyView.We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna +4 more
wiley +1 more source
The role of circular RNAs in regulating cytokine signaling in cancer
FEBS Open Bio, EarlyView.Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi +4 more
wiley +1 more source