Results 291 to 300 of about 2,378,379 (395)

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

Advanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson, Huy Hoang Nguyen, Keng‐Jung Lee, Nattarat Wongsuwan, Ayesha Tupe, Mengrou Lu, Mariah Lynn Arral, Anne Behre, Zihan Ling, Kathryn Ann Whitehead, Adam Walter Feinberg, Xi Ren, Si‐Yang Zheng   +12 more
wiley   +1 more source

Topological variety and self-sorting in homo- and heteroleptic Pd _<i>n</i> L_2<i>n</i> metallo-supramolecular assemblies. [PDF]

Chem Sci
Neukirch L, Clever GH.
europepmc   +1 more source

A Universal Biomimetic Approach for Making Artificial Antigen‐Presenting Cells for T Cell Activation

Advanced Functional Materials, EarlyView.
This study shows a biomimetic silica microcapsule (SMC) fabrication method under mild conditions for making artificial antigen‐presenting cells (aAPCs). Inspired by marine biomineralization, peptide‐mediated biosilicification enables silica shell formation on emulsion templates. The resulting SMCs possess a core–shell structure, controlled fluorescence
Fei Hou, Supun Ranaweera, Xiangke Li, Ruirui Qiao, Yue Hui, Chun‐Xia Zhao   +5 more
wiley   +1 more source

An engineered redox-switchable streptavidin mutein enables the high-affinity capture and efficient elution of biotinylated ligands. [PDF]

Protein Sci
Marangoni JM, Zutic A, Dhindsa A, Uche-Orji E, Wong SL, Ng KKS.   +5 more
europepmc   +1 more source

Enhancing Direct Solar Water Splitting via ALD of Multifunctional TiO2/Pt Nanoparticle Coatings With Engineered Interfaces to GaAs/GaInP Tandem Cells

Advanced Functional Materials, EarlyView.
Multifunctional atomic layer deposited coatings and interface treatments enhance direct solar water splitting on GaAs/GaInP tandem cells. Optimized TiO2/Pt nanoparticle bilayers ensure durability and catalytic efficiency with minimal optical losses, while H2 plasma pretreatments maximize photovoltage and interfacial charge extraction.
Tim F. Rieth, Verena Streibel, Oliver Bienek, Sergej Levashov, Johannes Dittloff, Kristof Möller, Johanna Eichhorn, Matthias M. May, Ian D. Sharp   +8 more
wiley   +1 more source

Rationalizing Spin-Crossover Properties of Substituted Fe (II) Complexes. [PDF]

Inorg Chem
Comas-Vilà G, Salvador P.
europepmc   +1 more source

Endocytic Programming via Porous Silicon Nanoparticles Enhances TLR4 Nanoagonist Potency for Macrophage‐Mediated Immunotherapy

Advanced Functional Materials, EarlyView.
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang, Huiying Li, Shuodan Huang, Linxuan Zhang, Yan Gao, Ruoran Wang, Xiaoyu Wang, Hélder A. Santos, Zhenyu Yin, Bing Xia   +9 more
wiley   +1 more source

Mathematical Framework to Identify Optimal Molecule Based on Virtual Ligand Strategy. [PDF]

J Chem Inf Model
Matsuoka W, Hirose K, Yamada R, Oki T, Iwata S, Maeda S.   +5 more
europepmc   +1 more source

Investigation of the Effects of Strain and Electric Field on the Spin‐State Energetics of Co‐Doped BaTiO3 and PbTiO3

Advanced Functional Materials, EarlyView.
Ab initio calculations using the r2SCAN functional show that biaxial strain does not alter the high spin preference of cobalt‐doped BaTiO3 and PbTiO3; a small compressive uniaxial strain however results in an equally favorable low spin state for BaTiO3 and thus bistable magnetism.
Oliver J. Conquest, Steefan Contractor, Leigh Weston, Catherine Stampfl   +3 more
wiley   +1 more source

Scavenger receptor CD163 multimerises to allow uptake of diverse ligands. [PDF]

Nat Commun
Zhou RX, Higgins MK.
europepmc   +1 more source