Results 51 to 60 of about 1,301,268 (279)

Tetra­aceto­nitrile­lithium tetra­iso­thio­cyanato­borate [PDF]

, 2013
The crystal structure of the title salt, [Li(CH3CN)4][B(NCS)4], is composed of discrete cations and anions. Both the Li and B atoms show a tetra­hedral coordination by four equal ligands. The aceto­nitrile and iso­thio­cyanate ligands are linear.
Bolte, Michael, Breunig, Jens Michael, Lerner, Hans-Wolfram, Wietelmann, Ulrich   +3 more
core   +1 more source

Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele, Calogero Virgone, Michaela Kuhlen, Sabine Irtan, Yves Reguerre, Malgorzata Krawczyk, Ewa Bien, Tal Ben‐Ami, Maja Cesen, Ricardo Lopez‐Almaraz, Andrea Ferrari, Gianni Bisogno, Dominik T. Schneider, Abbas Agaimy, Constantin Lapa, Hubert Ducou le Pointe, Rainer Claus, Catherine Daniel, Ines B. Brecht, Daniel Orbach   +19 more
wiley   +1 more source

Machine Learning Methods as a Cost-Effective Alternative to Physics-Based Binding Free Energy Calculations

Molecules
The rank ordering of ligands remains one of the most attractive challenges in drug discovery. While physics-based in silico binding affinity methods dominate the field, they still have problems, which largely revolve around forcefield accuracy and ...
Nupur Bansal, Ye Wang, Simone Sciabola
doaj   +1 more source

Coordination chemistry of amide-functionalised tetraazamacrocycles: structural, relaxometric and cytotoxicity studies [PDF]

, 2010
Three different tetraazamacrocyclic ligands containing four amide substituents that feature groups (namely allyl, styryl and propargyl groups) suitable for polymerisation have been synthesised.
Aime, Aime, Aime, Aime, Aime, Ali, Andrew J. P. White, Antoni, Beeta Balali-Mood, Behnam Azad, Bottrill, Bryson, Burdinski, Caravan, Cattaneo, Chapon, Cheng, Cilliers, De Leon-Rodriguez, De Leon-Rodriguez, Delgado, Faulkner, Fields, Gabriel, Guo, Hermann, Iten, Joachim H. G. Steinke, Jonathan Martinelli, Kaneshiro, Langereis, Major, Mani, Mark F. Lythgoe, Maumela, Montgomery, Moore, Muller, New, Oliver, Patrizia Ferretti, Pratesi, Rachael Panizzo, Ramon Vilar, Roosenburg, Schlesinger, Tan, Trokowski, Villaraza, Viola-Villegas, Viswanathan, Wu, Xu, Zhang, Zucchi   +54 more
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Mononuclear Cu(II) complexes of novel salicylidene Schiff bases: synthesis and mesogenic properties [PDF]

, 2015
Two new Schiff base ligands 1 and 2 (where 1 = 4-(2-hydroxybenzilidenamino)-phenyl-4-(decyloxy)-2-(pent-4-enyloxy)benzoate, 2 = 4-(4-(decyloxy)-2-hydroxybenziliden amino)-phenyl-4-(decyloxy)-2-(pent-4-enyloxy)benzoate) and their copper (Cu)(II) complexes
Badea, Valentin, Costisor, Otilia, Cretu, Carmen, Cseh, Liliana, Mehl, Georg, Sasca, Viorel, Shova, Sergiu, Szerb, Elisabeta I., Tang, Bai J.   +8 more
core   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Fuzzy virtual ligands for virtual screening [PDF]

, 2009
A new method to bridge the gap between ligand and receptor-based methods in virtual screening (VS) is presented. We introduce a structure-derived virtual ligand (VL) model as an extension to a previously published pseudo-ligand technique [1]: LIQUID [2 ...
Löwer, Martin, Schneider, Gisbert (Prof. Dr.), Tanrikulu, Yusuf, Weisel, Martin   +3 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Iron and Zinc in the Embryo and Endosperm of Rice (Oryza sativa L.) Seeds in Contrasting 2′-Deoxymugineic Acid/Nicotianamine Scenarios

Frontiers in Plant Science, 2018
Iron and Zn deficiencies are worldwide nutritional disorders that can be alleviated by increasing the metal concentration of rice (Oryza sativa L.) grains via bio-fortification approaches.
Pablo Díaz-Benito, Raviraj Banakar, Sara Rodríguez-Menéndez, Teresa Capell, Rosario Pereiro, Paul Christou, Paul Christou, Javier Abadía, Beatriz Fernández, Ana Álvarez-Fernández   +9 more
doaj   +1 more source