Results 51 to 60 of about 860,212 (198)

Ligand Substitution Dynamics [PDF]

open access: green, 1968
Cooper H. Langford, Thomas R. Stengle
openalex   +2 more sources

Identification of a small‐molecule ligand of β‐arrestin1 as an inhibitor of stromal fibroblast cell migration accelerated by cancer cells

open access: yesCancer Medicine, 2018
Stromal fibroblasts, which occupy a major portion of the tumor microenvironment, play an important role in cancer metastasis. Thus, targeting of these fibroblasts activated by cancer cells (carcinoma‐associated fibroblasts; CAFs) might aid in the ...
Kruthi Suvarna   +4 more
doaj   +1 more source

Galanin receptor ligands [PDF]

open access: yesSpringerPlus, 2015
The effect of galanin is mediated through three GPCR subtypes, GalR1-3. The limited number of specific ligands to the galanin receptor subtypes has hindered the understanding of the individual effects of each receptor subtype. This review summarizes the current data of the importance of the galanin receptor subtypes and receptor subtype specific ...
openaire   +3 more sources

Chelating Properties of N6O-Donors Toward Cu(II) Ions: Speciation in Aqueous Environments and Catalytic Activity of the Dinuclear Complexes

open access: yesMolecules
This study focuses on the use of three isostructural N6O donor ligands, specifically known to form complexes with copper ions, to chelate Cu(II) from aqueous solutions.
Andrea Cendron   +6 more
doaj   +1 more source

Nuclear Receptors and the Hidden Language of the Metabolome

open access: yesCells
Nuclear hormone receptors (NHRs) are a family of ligand-regulated transcription factors that control key aspects of development and physiology. The regulation of NHRs by ligands derived from metabolism or diet makes them excellent pharmacological targets,
Yujie Chen   +4 more
doaj   +1 more source

Ligand modulation of sidechain dynamics in a wild-type human GPCR

open access: yeseLife, 2017
GPCRs regulate all aspects of human physiology, and biophysical studies have deepened our understanding of GPCR conformational regulation by different ligands.
Lindsay D Clark   +9 more
doaj   +1 more source

The Electrostatic Model for Calculation of the Ligand Field Parameter of Octahedral Complexes. [PDF]

open access: bronze, 1956
Ole Bostrup   +3 more
openalex   +1 more source

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