Results 51 to 60 of about 1,747,583 (341)

Chelating Properties of N₆O-Donors Toward Cu(II) Ions: Speciation in Aqueous Environments and Catalytic Activity of the Dinuclear Complexes

Molecules
This study focuses on the use of three isostructural N6O donor ligands, specifically known to form complexes with copper ions, to chelate Cu(II) from aqueous solutions.
Andrea Cendron, Martina Chianese, Kamil Zarzycki, Paolo Ruzza, Claudia Honisch, Justyna Brasuń, Mauro Carraro   +6 more
doaj   +1 more source

Asymmetric Reactions of N-Phosphonyl/Phosphoryl Imines

Molecules, 2023
The asymmetric reactions of imines continued to attract the attention of the scientific community for decades. However, the stereoselective reactions of N-phosphonyl/phosphoryl imines remained less explored as compared to other N-substituted imines.
Devalina Ray, Suman Majee, Ram Naresh Yadav, Bimal Krishna Banik   +3 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Functional Studies of Sex Pheromone Receptors in Asian Corn Borer Ostrinia furnacalis

Frontiers in Physiology, 2018
Lepidopteran insects use sex pheromones for sexual communication. Pheromone receptors expressed on peripheral olfactory receptor neurons (ORNs) are critical part to detect the sex pheromones. In genus Ostrinia, several pheromone receptors were functional
Wei Liu, Xing-chuan Jiang, Song Cao, Bin Yang, Gui-rong Wang   +4 more
doaj   +1 more source

Structural Characterization of Alzheimer DNA Promoter Sequences from the Amyloid Precursor Gene in the Presence of Thioflavin T and Analogs

Crystals, 2022
Understanding DNA–ligand binding interactions requires ligand screening, crystallization, and structure determination. In order to obtain insights into the amyloid peptide precursor (APP) gene–Thioflavin T (ThT) interaction, single crystals of two DNA ...
Hristina Sbirkova-Dimitrova, Rusi Rusew, Nikola Kuvandjiev, Annie Heroux, Tzanko Doukov, Boris L. Shivachev   +5 more
doaj   +1 more source

GPCRdb in 2018: adding GPCR structure models and ligands

Nucleic Acids Res., 2017
G protein-coupled receptors are the most abundant mediators of both human signalling processes and therapeutic effects. Herein, we report GPCRome-wide homology models of unprecedented quality, and roughly 150 000 GPCR ligands with data on biological ...
Gáspár Pándy-Szekeres, Christian Munk, Ts. Tsonkov, Stefan Mordalski, K. Harpsøe, A. Hauser, A. Bojarski, David E. Gloriam   +7 more
semanticscholar   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Molecular docking analysis of anti-severe acute respiratory syndrome-Coronavirus 2 ligands against spike glycoprotein and the 3-chymotrypsin-like protease

Journal of Medical Signals and Sensors, 2021
Background: The severe acute respiratory syndrome-like disease coronavirus disease 2019 (COVID-19) is a disastrous global pandemic with 16,288,490 infected cases and 649,884 deaths. Until now, no effective treatments are found.
Ali Hassan Daghir Janabi
doaj   +1 more source

A Comprehensive Evaluation of the Activity and Selectivity Profile of Ligands for RGD-binding Integrins

Scientific Reports, 2017
Integrins, a diverse class of heterodimeric cell surface receptors, are key regulators of cell structure and behaviour, affecting cell morphology, proliferation, survival and differentiation.
Tobias G. Kapp, F. Rechenmacher, Stefanie Neubauer, O. Maltsev, E. A. Cavalcanti‐Adam, R. Zarka, U. Reuning, Johannes Notni, H. Wester, C. Mas-Moruno, J. Spatz, B. Geiger, H. Kessler   +12 more
semanticscholar   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source