Results 211 to 220 of about 120,350 (347)

Nephronectin (NPNT) is a Crucial Determinant of Idiopathic Pulmonary Fibrosis: Modulating Cellular Senescence via the ITGA3/YAP1 Signaling Axis

open access: yesAdvanced Science, EarlyView.
Through a comprehensive multi‐omics analysis, this study identifies a marked reduction in Nephronectin (NPNT) expression within fibrotic lung tissue. This reduction impairs the binding capability to the ITGA3 receptor, consequently causing YAP1 to persist in the cytoplasm, where it undergoes degradation.
Jiayu Guo   +20 more
wiley   +1 more source

Peroxisomal lignoceroyl-CoA ligase deficiency in childhood adrenoleukodystrophy and adrenomyeloneuropathy.

open access: green, 1988
Oscar Lazo   +5 more
openalex   +1 more source

Nanomedicine‐Driven Modulation of Reductive Stress for Cancer Therapy

open access: yesAdvanced Science, EarlyView.
This article introduces a novel therapeutic paradigm that deliberately induces reductive stress within tumor cells to exploit their unique biochemical vulnerabilities. It systematically reviews the underlying biological mechanisms, current detection and monitoring techniques, and emerging advanced nanotechnology platforms specifically designed to ...
Yumin Mao   +8 more
wiley   +1 more source

Dopamine D1 Receptor Contributes to Glucocorticoid‐Associated Osteonecrosis of Femoral Head Protection Through the ATF3/CHOP Axis to Inhibit Osteoblastic Apoptosis

open access: yesAdvanced Science, EarlyView.
This work identifies a novel mechanism by which dopamine D1 receptor (DRD1) contributes to the pathogenesis of glucocorticoid (GC)‐associated osteonecrosis of the femoral head (ONFH) through the regulation of osteoblastic apoptosis, indicating that DRD1 serves as a critical mediator of the crosstalk between the nervous and skeletal systems.
Kai Zheng   +11 more
wiley   +1 more source

Correlation between anthracycline structure and human DNA ligase inhibition [PDF]

open access: green, 1991
Giovanni Ciarrocchi   +4 more
openalex   +1 more source

Primer‐Disk‐Enabled DNA Data Storage System with Index and Record‐Many‐Read‐Many Features

open access: yesAdvanced Science, EarlyView.
A primer‐disk‐enabled DNA data storage system is introduced, which allows for append‐recording of DNA files on demand, retrieval via inkjet printed QR code, and multiple ramdom read of DNA information via solid‐phase PCR. The hiearchical system with index and record‐many‐read‐many features paves the way for the practical use of DNA data storage ...
Jiaxiang Ma   +5 more
wiley   +1 more source

Purification and characterization of the VanB ligase associated with type B vancomycin resistance in Enterococcus faecalis V583 [PDF]

open access: bronze, 1994
Djalal Meziane‐Cherif   +4 more
openalex   +1 more source

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