Results 121 to 130 of about 104,318 (277)

Three-dimensional morphological and fluorescent imaging of zebrafish with a continuous-rotational light-sheet microscope

Journal of Innovative Optical Health Sciences
Light-sheet fluorescence microscopy (LSFM) has been widely used to image the three-dimensional (3D) structures and functions of various millimeter-size bio-specimen such as zebrafish.
Dongmin Zhang, Guang Yang, Yao Tan, Chong Chen, Jie Zhang, Hui Li   +5 more
doaj   +1 more source

Tailored Sample Mounting for Light-Sheet Fluorescence Microscopy of Clarified Specimens by Polydimethylsiloxane Casting

Frontiers in Neuroanatomy, 2019
The combination of biological tissue clearing methods with light-sheet fluorescence microscopy (LSFM) allows acquiring images of specific biological structures of interest at whole organ scale and microscopic resolution.
Antonino Paolo Di Giovanna, Caterina Credi, Caterina Credi, Alessandra Franceschini, Marie Caroline Müllenbroich, Ludovico Silvestri, Ludovico Silvestri, Francesco Saverio Pavone, Francesco Saverio Pavone, Francesco Saverio Pavone   +9 more
doaj   +1 more source

Ultrastructural characterization (morphological and topochemical) of wood pulp fibres [PDF]

, 2007
Different electron microscopy techniques including SEM (scanning electron microscopy), FE-SEM (field emission-scanning electron microscopy), TEM (transmission electron microscopy) and Immuno-gold TEM (immuno-gold transmission electron microscopy) were ...
Fernando, Dinesh
core  

The case for emulating insect brains using anatomical "wiring diagrams" equipped with biophysical models of neuronal activity

, 2018
Developing whole-brain emulation (WBE) technology would provide immense benefits across neuroscience, biomedicine, artificial intelligence, and robotics.
Collins, Logan Thrasher
core   +1 more source

Multiscale Hybrid Surface Topographies Orchestrate Immune Regulation, Antibacterial Defense, and Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
Hybrid wrinkled topographies coordinate immune, tissue, and bacterial interactions. The surfaces promote osteointegration, tune macrophage polarization, and inhibit biofilm formation, highlighting a multifunctional strategy for next‐generation implant design.
Mohammad Asadi Tokmedash, Jacob Robins, J. Scott VanEpps, Minji Kim, Jouha Min   +4 more
wiley   +1 more source

Preliminary Study of a Ninj1‐Loaded Bimodal Ultrasound/NIR Fluorescence Targeted Molecular Probe for Diagnosing Early‐Stage Inflammation in Coronary Microvascular Dysfunction

Advanced Healthcare Materials, EarlyView.
Coronary microvascular dysfunction (CMD) targeting remains a challenge for precise diagnosis. This work presents a dual‐modal nanoprobe (T‐IR780‐NBs) that combines ultrasound contrast with near‐infrared fluorescence. This technology utilizes proteomics‐derived antibodies that specifically localize to inflamed and injured cardiac tissue, enabling ...
Xiaohui Xu, Lina Guan, Baihetiya Tayier, Chen Yuan, Shangke Chen, Qi Shi, Yuming Mu   +6 more
wiley   +1 more source

Three-dimensional virtual refocusing of fluorescence microscopy images using deep learning

, 2019
Three-dimensional (3D) fluorescence microscopy in general requires axial scanning to capture images of a sample at different planes. Here we demonstrate that a deep convolutional neural network can be trained to virtually refocus a 2D fluorescence image ...
Ben-David, Eyal, Bentolila, Laurent A., Luo, Yilin, Ozcan, Aydogan, Pritz, Christian, Rivenson, Yair, Wang, Hongda, Wu, Yichen   +7 more
core   +1 more source

Platelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen, Jiali Lin, Jiapeng Li, Yiwei Hu, Jiansen Su, Yu Miao, Lanlan Wang, Qian Tang, Changqing Zhang, Junhui Yin   +9 more
wiley   +1 more source

A Quantitative Printability Framework for Programmable Assembly of Pre‐Vascular Patterns via Laser‐Induced Forward Transfer

Advanced Healthcare Materials, EarlyView.
Laser‐Induced Forward Transfer (LIFT) is presented as a powerful micropatterning tool. An objective printability framework is developed to assess optimal printing parameter combinations. The technology is further explored for its ability to deterministically deposit microdroplets at predefined locations following CAD designs, enabling the patterning of
Cécile Bosmans, Núria Ginés Rodriguez, Ulisses Jesús Gutiérrez Hernández, David Fernandez Rivas, Marcel Karperien, Jos Malda, Liliana Moreira Teixeira, Riccardo Levato, Jeroen Leijten   +8 more
wiley   +1 more source

LIGHT SHEET FLUORESCENCE MICROSCOPY COMBINED WITH OPTICAL CLEARING METHODS AS A NOVEL IMAGING TOOL IN BIOMEDICAL RESEARCH

European Medical Journal Innovations, 2017
In the past decade, imaging has advanced to become a crucial tool in fundamental and biomedical research and it has become increasingly important to be able to image whole organs with single cell resolution.
Julia Bode, Thomas Krüwel, Björn Tews
doaj