Results 101 to 110 of about 6,151,952 (306)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Applications and limitations of centers for disease control and prevention miniature light traps for measuring biting densities of African malaria vector populations : a pooled-analysis of 13 comparisons with human landing catches [PDF]

, 2015
Measurement of densities of host-seeking malaria vectors is important for estimating levels of disease transmission, for appropriately allocating interventions, and for quantifying their impact.
Govella, Nicodem, Nicodem Govella, Salim Abdullah, Seyoum, Aklilu, Huho, Bernadette J, Killeen, Gerry, Briët, Olivier J. T., Bayoh, Nabie, Sikaala, Chadwick H., Smith, Thomas A., Sikaala, Chadwick H, John E Gimnig, Killeen, Gerry F, Gimnig, John E, Diallo, Diadier A, Abdullah, Salim, Gimnig, John E., Diallo, Diadier A., Diadier A Diallo, Gerry F Killeen, Sikaala, Chadwick, Aklilu Seyoum, Nabie Bayoh, Killeen, Gerry F., Huho, Bernadette J., Briët, Olivier J T, Chadwick H Sikaala, Olivier J T Briët, Bernadette J Huho, Smith, Thomas A, Thomas A Smith   +30 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

SURFACE DISINFECTION BY EXPOSURE TO GERMICIDAL UV LIGHT

Indian Journal of Medical Microbiology, 2008
The present study was aimed to design a simple model to check efficacy of germicidal UV tube, to standardise the position, distance and time for UV light and also to find out its efficacy against medically important bacteria, the bacterial spores and fungi.
Katara, G, Hemvani, N, Chitnis, S, Chitnis, V, Chitnis, DS   +4 more
openaire   +2 more sources

Lead Exposure and Prevention Advisory Committee (LEPAC) : 2021 annual report to U.S. Department of Health and Human Services [PDF]

The objective of the Lead Exposure and Prevention Advisory Committee (LEPAC) is to review research and federal programs and services related to lead poisoning and to identify effective services and best practices for addressing and preventing lead ...

core  

Parental perceptions of exposure to tobacco smoke: a new tool to shed light on parental smoking behaviour

, 2018
Background Around 40% of children worldwide are exposed to tobacco smoke by their parents. Interventions to reduce exposure have limited success. Parental reports often do not match biomarker reports of children's exposure.
Laura (Leah) Rosen, Vicki Myers Gamliel, Shoshanah Shiloh   +2 more
core   +1 more source

Adaptation of the Light Exposure Behavior Assessment into Turkish: A Validity and Reliability Study

Türk Uyku Tıbbı Dergisi
Objective: This study aimed to translate and culturally adapt the light exposure behavior assessment (LEBA) questionnaire into Turkish and evaluate its psychometric properties in terms of reliability and validity.
Altuğ Didikoğlu, Zeynep Kayar, İclal Arabacıoğlu, Burcu Gemici, Safa Kemal Kaptan, Betül Yılmaz, Muazzez Nihal Öykü Ülker, Pelin Calpbinici   +7 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Wavefront shaping of a Bessel light field enhances light sheet microscopy with scattered light [PDF]

, 2014
The project was supported by the UK Engineering and Physical Sciences Research Council, RS MacDonald Charitable Trust, SULSA, and the St. Andrews 600th anniversary BRAINS appeal. K. D.
Vettenburg, T.; id_orcid, J. Nylk, K. Dholakia, Nylk, J., C. Mitchell, Vettenburg, T., Gunn-Moore, F. J., T. Vettenburg, Mitchell, C., Dholakia, K., Nylk, J.; id_orcid, F. J. Gunn-Moore   +11 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source