Results 21 to 30 of about 136,404 (276)

Sidelobe suppression in structured light sheet fluorescence microscopy by the superposition of two light sheets. [PDF]

Biomed Opt Express, 2023
Light sheet microscopy has emerged as a powerful technique for three-dimensional and long-term vivo imaging within neuroscience and developmental biology.
Han Q, Shi J, Shi F.
europepmc   +2 more sources

Enhancing brain image quality with 3D U-net for stripe removal in light sheet fluorescence microscopy. [PDF]

Brain Inform
Light Sheet Fluorescence Microscopy (LSFM) is increasingly popular in neuroimaging for its ability to capture high-resolution 3D neural data. However, the presence of stripe noise significantly degrades image quality, particularly in complex 3D stripes ...
Li C, Li Y, Zhao H, Ding L.
europepmc   +2 more sources

Using tissue clearing and light sheet fluorescence microscopy for the three-dimensional analysis of sensory and sympathetic nerve endings that innervate bone and dental tissue of mice. [PDF]

J Comp Neurol
Bone and dental tissues are richly innervated by sensory and sympathetic neurons. However, the characterization of the morphology, molecular phenotype, and distribution of nerves that innervate hard tissue has so far mostly been limited to thin ...
Thai J, Fuller-Jackson JP, Ivanusic JJ.
europepmc   +2 more sources

An MR-based brain template and atlas for optical projection tomography and light sheet fluorescence microscopy in neuroscience. [PDF]

Front Neurosci
Introduction Optical Projection Tomography (OPT) and light sheet fluorescence microscopy (LSFM) are high resolution optical imaging techniques, ideally suited for ex vivo 3D whole mouse brain imaging.
Willekens SMA, Morini F, Mediavilla T, Nilsson E, Orädd G, Hahn M, Chotiwan N, Visa M, Berggren PO, Ilegems E, Överby AK, Ahlgren U, Marcellino D.   +12 more
europepmc   +2 more sources

Fifty high-content light sheet fluorescence microscopy datasets of Tribolium castaneum embryogenesis [PDF]

Scientific Data
The red flour beetle (Tribolium castaneum) is a key model organism in developmental biology, genetics, and agricultural research. To address the limited availability of high-quality microscopy data documenting its embryonic morphogenesis, we assembled ...
Frederic Strobl, Pinelopi Goumenaki, Kristina Mirkes, Henrik Tonner, Mariia Golden, Julia Ratke, Franziska Krämer, Stefan Münster, Ernst H. K. Stelzer   +8 more
doaj   +2 more sources

Improved image contrast in nonlinear light-sheet fluorescence microscopy using i $$^2$$ 2 PIE Pulse compression [PDF]

Scientific Reports
Nonlinear microscopy has become an invaluable tool for biological imaging, offering high-resolution visualization of biological specimens. In this manuscript, we present the application of a spectral phase measurement technique, i $$^2$$ 2 PIE, to ...
Imraan Badrodien, Pieter H. Neethling, Gurthwin W. Bosman   +2 more
doaj   +2 more sources

Multi-Scale Light-Sheet Fluorescence Microscopy for Fast Whole Brain Imaging [PDF]

Frontiers in Neuroanatomy, 2021
Whole-brain imaging has become an increasingly important approach to investigate neural structures, such as somata distribution, dendritic morphology, and axonal projection patterns.
Zhouzhou Zhang, Zhouzhou Zhang, Xiao Yao, Xiao Yao, Xinxin Yin, Xinxin Yin, Zhangcan Ding, Tianyi Huang, Yan Huo, Runan Ji, Hanchuan Peng, Hanchuan Peng, Zengcai V. Guo, Zengcai V. Guo   +13 more
doaj   +2 more sources

Quantitative analysis of illumination and detection corrections in adaptive light sheet fluorescence microscopy. [PDF]

Biomed Opt Express, 2022
Light-sheet fluorescence microscopy (LSFM) is a high-speed, high-resolution and minimally phototoxic technique for 3D imaging of in vivo and in vitro specimens.
Rai MR, Li C, Greenbaum A.
europepmc   +2 more sources

A vascularized breast cancer spheroid platform for the ranked evaluation of tumor microenvironment-targeted drugs by light sheet fluorescence microscopy. [PDF]

Nat Commun
Targeting the supportive tumor microenvironment (TME) is an approach of high interest in cancer drug development. However, assessing TME-targeted drug candidates presents a unique set of challenges.
Ascheid D, Baumann M, Pinnecker J, Friedrich M, Szi-Marton D, Medved C, Bundalo M, Ortmann V, Öztürk A, Nandigama R, Hemmen K, Ergün S, Zernecke A, Hirth M, Heinze KG, Henke E.   +15 more
europepmc   +2 more sources

Nondestructive 3D Pathology with Light-Sheet Fluorescence Microscopy for Translational Research and Clinical Assays. [PDF]

Annu Rev Anal Chem (Palo Alto Calif), 2023
In recent years, there has been a revived appreciation for the importance of spatial context and morphological phenotypes for both understanding disease progression and guiding treatment decisions.
Liu JTC, Glaser AK, Poudel C, Vaughan JC.   +3 more
europepmc   +2 more sources