Childhood maltreatment and amygdala connectivity in methamphetamine dependence: a pilot study. [PDF]
IntroductionChildhood maltreatment, a well-known risk factor for the development of substance abuse disorders, is associated with functional and structural abnormalities in the adult brain, particularly in the limbic system.
Dean, Andy C +3 more
core +2 more sources
Regional differences in the coupling between resting cerebral blood flow and metabolism may indicate action preparedness as a default state. [PDF]
Although most functional neuroimaging studies examine task effects, interest intensifies in the "default" resting brain. Resting conditions show consistent regional activity, yet oxygen extraction fraction constancy across regions.
Alavi, Abass +5 more
core +2 more sources
EMDR therapy for PTSD after motor vehicle accidents: meta-analytic evidence for specific treatment [PDF]
Motor vehicle accident (MVA) victims may suffer both acute and post-traumatic stress disorders (PTSD). With PTSD affecting social, interpersonal and occupational functioning, clinicians as well as the National Institute of Health are very interested in ...
Boccia, Maddalena +4 more
core +1 more source
ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li +9 more
wiley +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
Interaction and synchronization of rhythms in a model of the brain limbic system [PDF]
The purpose of this study is to build a mathematical network model for interaction of rhythms in the limbic system of the brain, when pathological epileptiform activity is spreading from the focus. Methods.
Kapustnikov, Anton Aleksandrovich +3 more
doaj +1 more source
Modelling the Effect of Dorsal Raphe Serotonin Neurons on Patience for Future Rewards [PDF]
Serotonin is a neurotransmitter that is implicated in many basic human functions and behaviours and is closely associated with happiness, depression and reward processing.
Porr, Bernd, Sutherland, Marc
core +1 more source
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini +7 more
wiley +1 more source
Neural correlates of outcome of the psychotherapy compared to antidepressant therapy in anxiety and depression disorders: a meta-analysis [PDF]
The most prevalent mental disorders, anxiety and depression, are commonly associated with structural and functional changes in the fronto-limbic brain areas.
Aceto, Paola +6 more
core +6 more sources

