Results 61 to 70 of about 158,928 (298)

Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen, Jing Zhang, Xinyue Zhou, Xiaoxiao Yu, Haodong Shang, Shufan Chen, Lulu Zhen, Jinru Wu, Guanlian Hu, Xiaoyan Zhu, Zhan Sun, Yiren Wang, Jiahui Wang, Jie Lv, Xue Zhao, Yingna Zhang, Wei Guo, Ying Peng, Feng Gao   +18 more
wiley   +1 more source

A structural connectivity atlas of limbic brainstem nuclei

Frontiers in Neuroimaging, 2023
BackgroundUnderstanding the structural connectivity of key brainstem nuclei with limbic cortical regions is essential to the development of therapeutic neuromodulation for depression, chronic pain, addiction, anxiety and movement disorders.
Simon Levinson, Simon Levinson, Michelle Miller, Ahmed Iftekhar, Monica Justo, Daniel Arriola, Wenxin Wei, Saman Hazany, Josue M. Avecillas-Chasin, Taylor P. Kuhn, Andreas Horn, Andreas Horn, Andreas Horn, Ausaf A. Bari   +13 more
doaj   +1 more source

Central neuropathic pain in paraplegia alters movement related potentials [PDF]

, 2018
Objectives: Spinal Cord Injured (SCI) persons with and without Central Neuropathic Pain (CNP) show different oscillatory brain activities during imagination of movement.
Fraser, Matthew, Hasan, Muhammad Abul, Jarjees, Mohammed, Miyakoshi, Makoto, Vuckovic, Aleksandra   +4 more
core   +1 more source

Clinical Characteristics and Outcomes of Early‐Onset Versus Late‐Onset LGI1‐Antibody Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Leucine‐rich glioma‐inactivated 1 antibody (LGI1‐Ab) encephalitis predominantly affected older individuals, but has also been reported in younger patients. However, the demographic, clinical, and prognostic characteristics of early‐onset LGI1‐Ab encephalitis have yet to be systematically elucidated. This study aims to systematically
Yu Kong, Shasha Yu, Jing Zhang, Yu Zu, Yujing Zhang, Jing Lv, Xuyang Cao, Xuedan Feng   +7 more
wiley   +1 more source

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon   +22 more
wiley   +1 more source

Functional anatomy of the limbic system structures involved in the development of post-traumatic stress disorder: analysis of anatomical and clinical studies

Неврология, нейропсихиатрия, психосоматика
We present an analysis of anatomical and clinical studies investigating the morphological and functional characteristics of various structures of the limbic system involved in the development of post-traumatic stress disorder (PTSD).
V. N. Nikolenko, A. S. Osadchiy, A. K. Lobanova, T. A. Isakova, N. A. Zharov, N. V. Zharova   +5 more
doaj   +1 more source

Takotsubo syndrome associated with autoimmune limbic encephalitis: a case report

BMC Cardiovascular Disorders, 2021
Background Central nervous system diseases are common triggers of Takotsubo syndrome. We herein report a rare case of Takotsubo syndrome associated with autoimmune limbic encephalitis.
Yuki Kakinuma, Taro Kimura, Yoshiki Sakae, Satomi Kubota, Kenjiro Ono, Ryuta Kinno   +5 more
doaj   +1 more source

Domain Specific Placebo Response in the Modified Friedreich's Ataxia Rating Scale

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The placebo response in clinical trials in ataxias complicates outcome interpretation and potentially obscures genuine treatment effects. We analyzed placebo group data from past trials in Friedreich Ataxia and observed notable responses in appendicular items, in contrast to minimal changes in axial function, as measured by respective ...
Christian Rummey, Jennifer M. Farmer, David R. Lynch   +2 more
wiley   +1 more source

Injury to the circuit of Papez: An overlooked cause of recurrent seizures

Clinical Case Reports, 2023
Key Clinical Message Papez' circuit is a unique neural pathway in the limbic system that is correlated with seizure activity. Injuries affecting Papez' circuit are often small and unusual in location but can be identifiable in MRI and functional imaging ...
Loai Aker, Surjith Vattoth, Yahya Paksoy
doaj   +1 more source

Levothyroxine effects on depressive symptoms and limbic glucose metabolism in bipolar disorder: a randomized, placebo-controlled positron emission tomography study. [PDF]

, 2016
Adding supraphysiologic doses of levothyroxine (L-T4) to standard treatment for bipolar depression shows promise, but the mechanisms underlying clinical improvement are unknown.
Adli, M, Bauer, M, Berman, S, Hellemann, GS, London, ED, Pilhatsch, M, Plotkin, M, Schlagenhauf, F, Stamm, T, Whybrow, PC   +9 more
core