Results 131 to 140 of about 6,338,079 (289)

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Effectiveness of Xpert MTB/RIF and the Line Probe Assay tests for the rapid detection of drug-resistant tuberculosis in the Central African Republic. [PDF]

PLOS Glob Public Health, 2023
Farra A, Koula K, Jolly BL, Gando HG, Ouarandji LM, Mossoro-Kpinde CD, Manirakiza A, Simelo JP, de Dieu Iragena J.   +8 more
europepmc   +1 more source

Line probe assay for differentiation within Mycobacterium tuberculosis complex. Evaluation on clinical specimens and isolates including Mycobacterium pinnipedii

, 2009
Udgivelsesdato: 2009-nullA line probe assay (GenoType MTBC) was evaluated for species differentiation within the Mycobacterium tuberculosis complex (MTBC).
Bek, Dorte, Kjeldsen, Marianne Kirstine, Thomsen, Vibeke Østergaard, Priemé, Anders, Rasmussen, Erik Michael, Marianne Kirstine Kjeldsen, Vibeke Østergaard Thomsen, Dorte Bek, Anders Priemé, Erik Michael Rasmussen   +9 more
core   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Primer and probe sequences for PCR and RPA assay.

, 2018
Primer and probe sequences for PCR and RPA assay.
Hongxia Chen (420196), Xiaoling Li (129705), Jiameng Li (6009461), Yong Qi (429532), Suyun Liu (3955865), Qiong Yin (6009458), Wenwen Zeng (6009464), Shulong Zheng (6009467), Yuexi Li (6009470), Yinxiu Shao (6009449), Jixian Rao (6009452), Wanpeng Shen (6009455)   +11 more
core   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Primer and probe sequences for the AGR assay.

, 2019
Primer and probe sequences for the AGR assay.
Jacqueline R. M. A. Maasch (7022375), Thomas B. Nutman (113195), Eric Dahlstrom (451989), Nils Pilotte (187651), Alice V. Easton (4778655), Steven A. Williams (187671)   +5 more
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Primer and probe sequences of the quadruplex assay.

, 2016
Primer and probe sequences of the quadruplex assay.
Joseph D. Thiriot (3219381), Benjamin A. Satterfield (554677), Daniel B. Nelson (3219378), Emily S. Moore (3219369), Kim L. O'Neill (3219375), Cynthia S. Lew (2825468), Annette J. Bunnell (3219357), David S. Drake (3219366), Richard A. Robison (2116180), Michael J. Heder (3219363), Jordon K. March (3219360), Chinn-Woan Lowe (3219372)   +11 more
core   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

FEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini, Freia S. Buus, Benjamin Schuler, Birthe B. Kragelund   +3 more
wiley   +1 more source