Results 121 to 130 of about 10,510,472 (349)
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed+8 more
wiley +1 more source
Aircraft Selection Using Linear Physical Programming
Selection of the most appropriate aircraft is an important decision affecting the profitability of an airline. This decision requires the consideration of many different criteria including seat capacity, fuel consumption and range.
Mehmet Ali Ilgın
doaj
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho+11 more
wiley +1 more source
Finding a Feasible Solution for a Simple LP Problem using Agents [PDF]
In this paper we will describe a Multi-Agent System which is capable of finding a feasible solution of a specially structured linear programming problem.
Bruin, A. de+3 more
core +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias+12 more
wiley +1 more source
Linear Programming by Solving Systems of Differential Equations Using Game Theory [PDF]
In this paper we will solve some linear programming problems by solving systems of differential equations using game theory. The linear programming problem must be a classical constraints problem or a classical menu problem, i.e.
Ciuiu, Daniel
core +1 more source
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner+6 more
wiley +1 more source
The core of operations research activity focuses on creating and using models. These models may be linear models, non-linear models, dynamic models, and others.
Maissam Jdid
doaj +1 more source