Results 21 to 30 of about 38,540 (200)
The emergence of plasmid-borne cfr-mediated linezolid resistant-staphylococci in Vietnam
Journal of Global Antimicrobial Resistance, 2020 Objectives: Linezolid is one of the last resort antibiotics effectively used in the treatment of infections caused by multidrug-resistant Gram-positive bacteria.
Le Thuy Thi Nguyen +12 more
doaj +1 more source
Антибиотики и Химиотерапия, 2020 To predict the anti-mutant effects of antibiotic combinations against Staphylococcus aureus, the mutant prevention concentrations (MPCs) of linezolid and daptomycin were determined at a linezolid-to-daptomycin concentration ratio that corresponds to the ...
K. N. Alieva +3 more
doaj +3 more sources
Incidence and risk factors of linezolid-induced lactic acidosis
International Journal of Infectious Diseases, 2015 Background: The use of linezolid has increased with the emergence of multidrug-resistant bacteria. Serum lactic acidosis has been reported as a serious side effect of linezolid use, therefore we evaluated the incidence and characteristics of linezolid ...
Jae Hyoung Im +3 more
doaj +1 more source
Characterization of In Vitro Resistance to Linezolid in Mycobacterium abscessus
Microbiology Spectrum, 2023 Single-step selection of Mycobacterium abscessus mutants resistant to linezolid yielded high-level resistance at a low frequency that was associated with mutations in 23S rRNA or the ribosomal protein L3.
Dereje A. Negatu +3 more
doaj +1 more source
The in vitro antimicrobial activity of linezolid against unconventional pathogens [PDF]
PeerJLinezolid is an oxazolidinone antibiotic that is mainly permitted to treat Gram-positive bacterial infections. Recent studies have shown that linezolid also has antibacterial effects on several other bacteria outside the package insert, including ...
Ting Wang +5 more
doaj +2 more sources
International Journal of Clinical Practice, 2001 SUMMARYMultiple antibiotic resistance is increasing worldwide in Gram‐positive bacteria, especially in hospitals. Problem organisms include multiply resistant strains of pneumococci,Staphylococcus aureusand enterococci; for many of these the glycopeptide vancomycin has become the treatment of last resort.
openaire +2 more sources
A possible interaction between linezolid and digoxin: A case report of therapeutic drug monitoring
Saudi Pharmaceutical Journal, 2020 Drug-drug interactions lead to altered clinical effects, including adverse reactions. Therapeutic drug monitoring of digoxin is necessary due to its narrow therapeutic range.
Zhu Yulin +3 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales +11 more
wiley +1 more source
Advanced Science, EarlyView.A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li +7 more
wiley +1 more source
Model Based Identification of Linezolid Exposure–toxicity Thresholds in Hospitalized Patients
Frontiers in Pharmacology, 2021 Evidence supports linezolid therapeutic drug monitoring as the exposure–response relationship has been identified for toxicity among patients receiving linezolid, but the data to establish the upper limit are limited and the published toxicity thresholds
Jie Fang +13 more
doaj +1 more source