Results 71 to 80 of about 64,259 (224)

Extracorporeal Shockwave Therapy for Diabetes Related Foot Ulcers: A Pilot Three‐Arm Double‐Blinded Randomised Controlled Trial

International Wound Journal, Volume 22, Issue 12, December 2025.
ABSTRACT There is an urgent need for effective interventions to aid diabetes‐related foot ulcer (DFU) healing. This study aimed to test the deliverability of a proposed trial of extracorporeal shockwave therapy (ESWT) for DFU healing. A pilot double‐blinded randomised controlled trial.
L. Hitchman, R. Lathan, B. Ravindhran, M. Sidapra, J. Long, A. Cowling, A. Keding, J. Watson, C. Iglesias, G. Smith, M. Twiddy, D. Russell, I. C. Chetter   +12 more
wiley   +1 more source

A New Kind of Quinonic-Antibiotic Useful Against Multidrug-Resistant S. aureus and E. faecium Infections [PDF]

, 2018
Indexación: Scopus.A rapid emergence of resistant bacteria is occurring worldwide, endangering the efficacy of antibiotics and reducing the therapeutic arsenal available for treatment of infectious diseases. In the present study, we developed a new class
Alarcón, P., Andrades-Lagos, J., Bollo Dragnic, S., Campanini-Salinas, J., Choquesillo-Lazarte, D., Faúndez, M., Gonzalez Rocha, G., Kogan, M., Mella, J., Recabarren Gajardo, G., Salas-Huenuleo, E., Silva, F., Vidal, R., Vásquez-Velásquez, D.   +13 more
core   +1 more source

Antimicrobial‐Resistant Bacteria in Environmental Samples From a Rural District Focused on Large‐Scale Agricultural Production

Tropical Medicine &International Health, Volume 30, Issue 12, Page 1269-1282, December 2025.
ABSTRACT Antimicrobial resistance is a growing concern, especially in regions with intense agricultural production. This study investigates the presence of antimicrobial‐resistant bacteria in Caramuru, Espírito Santo state, a rural district focused on large‐scale agricultural production in Brazil. Samples of water, soil, animal faeces and environmental
Davi Abreu Carvalho Mothé, Adryene Nunes Castro, Mariah Zanon Novaes, Francisco Ozório Bessa‐Neto, Rodrigo Cayô da Silva, Creuza Rachel Vicente, Glauciomar Buss, Sarah Santos Gonçalves, Kênia Valéria dos Santos   +8 more
wiley   +1 more source

Linezolid-induced black hairy tongue: a case report

Journal of Medical Case Reports, 2013
Introduction Linezolid-induced black hairy tongue has been rarely reported. The purpose of this paper is to report a case of linezolid-induced black hairy tongue and review the literature.
Khasawneh Faisal Abdullah, Moti Dereje Fikremariam, Zorek Joseph Anthony   +2 more
doaj   +1 more source

All‐Oral Shorter Treatment Regimens for Multidrug‐ and Rifampicin‐Resistant Tuberculosis: Evaluating Their Effectiveness, Safety, and Impact on the Quality of Life of Patients in Lao PDR

Tropical Medicine &International Health, Volume 30, Issue 12, Page 1340-1353, December 2025.
ABSTRACT Background Drug‐resistant tuberculosis remains a major public health challenge in Lao PDR, with low second‐line treatment uptake and suboptimal outcomes. To improve effectiveness, safety, and tolerability, a shorter all‐oral regimen for multidrug‐ and rifampicin‐resistant tuberculosis (MDR/RR‐TB) was introduced under the TDR Short, all‐Oral ...
Vibol Iem, Sakhone Suthepmany, Vongkham Inthavong, Anousone Sisouvanh, Khamloun Choumlivong, Kyung Hyun Oh, Philipp du Cros, Fatimata Bintou Sall, Corinne S. Merle, Jacques Sebert, Donekham Inthavong   +10 more
wiley   +1 more source

Synthesis of 1,4-Disubstituted Mono and Bis-triazolocarbo-acyclonucleoside Analogues of 9-(4-Hydroxybutyl)guanine by Cu(I)-Catalyzed Click Azide-Alkyne Cycloaddition [PDF]

, 2011
A series of novel mono-1,2,3-triazole and bis-1,2,3-triazole acyclonucleoside analogues of 9-(4-hydroxybutyl)guanine was prepared via copper(I)-catalyzed 1,3-dipolar cycloaddition of N-9 propargylpurine, N-1-propargylpyrimidines/as-triazine with the ...
Engels, Joachim W., Krim, Jamal, Taourirte, Mohamed   +2 more
core   +2 more sources

Rational Design and Antimycobacterial Evaluation of Aryl Sulfonamide–Linked Isoniazid Hydrazones Against Mycobacterium Tuberculosis

ChemMedChem, Volume 20, Issue 21, November 6, 2025.
Molecular docking shows that ligands 8 (a–i) adopt a U‐shaped geometry in the InhA active site, enabling stronger interactions than 7 (j–r). Surprisingly, both sets display similar potency, indicating that factors like electronic effects or solvation also influence anti‐TB activity.
Mukanda Gedeon Kadima, Sahil Mishra, Gobind Kumar, Pule Seboletswe, Afsana Kajee, Ankit, Françoise Roquet‐Banères, Maëlle Foubert, Laurent Kremer, Rajshekhar Karpoormath, Parvesh Singh   +10 more
wiley   +1 more source

Combined Use of Broad-Spectrum Antibiotics in Phthisiology

Фундаментальная и клиническая медицина
Aim. To investigate pharmacokinetic and pharmacodynamic interactions of levofloxacin, kanamycin and linezolid in combined chemotherapy of multidrug-resistant tuberculosis.Materials and Methods.
D. S. Vailenko, T. P. Tananakina, Yu. G. Pustovoy, V. V. Baranova, V. I. Shmatkov, A. R. Zanin   +5 more
doaj   +1 more source

Impact of time to appropriate therapy on mortality in patients with vancomycin-intermediate Staphylococcus aureus infection [PDF]

, 2016
Despite the increasing incidence of vancomycin-intermediate Staphylococcus aureus (VISA) infections, few studies have examined the impact of delay in receipt of appropriate antimicrobial therapy on outcomes in VISA patients.
Burnham, Carey-Ann D, Burnham, Jason P, Kollef, Marin H, Warren, David K   +3 more
core   +2 more sources

Chronic Hip Arthritis Secondary to Mycobacterium brisbanense in an Immunocompetent Pediatric Patient: A Case Report

ACR Open Rheumatology, Volume 7, Issue 11, November 2025.
A 12 year old boy presented with chronic left hip pain unresponsive to antibiotics. Laboratory tests showed raised white blood cells and C‐reactive protein. MRI hips showed left hip synovitis. Synovial biopsy showed infection with Mycobacterium brisbanense.
Soon Yap Lee, Haema Shunmugarajoo, Shashank Raghunandanan, Jasmeer Kaur, Gurkireth Kaur   +4 more
wiley   +1 more source