Results 81 to 90 of about 60,035 (201)

Enterococcal periprosthetic joint infection: clinical and microbiological findings from an 8-year retrospective cohort study [PDF]

, 2019
BACKGROUND: Treatment of enterococcal periprosthetic joint infections (PJI) is challenging due to non-standardized management strategies and lack of biofilm-active antibiotics. The optimal surgical and antimicrobial therapy are unknown.
Akgün, Doruk, Perka, Carsten, Renz, Nora, Trampuz, Andrej, Trebse, Rihard   +4 more
core   +1 more source

Molecular Mechanisms of Resistance and Treatment Efficacy of Delamanid Against Mycobacterium tuberculosis: A Systematic Review

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Tuberculosis (TB) remains a major global health problem, and treatment progress is increasingly threatened by rising multidrug‐resistant tuberculosis (MDR‐TB). Delamanid (DLM), a nitroimidazole drug, has shown good efficacy and safety against both drug‐susceptible and drug‐resistant Mycobacterium tuberculosis (Mtb) strains.
Md. Mahmudul Islam, Md. Zahid Hasan, Md. Touki Tahamid Tusar, Md. Yeamin Hossain, Md. Motaher Hossain, Md. Abdulla Al Jubayed, Md. Jubaer‐Al‐Abedin, Sheikh Soikot, Shanzida Akther, Jahid Bhuyian, Hafizur Rahman Gazi, B. M. Mahmudul Hasan, Md. Shofiul Azam, Md. Enamul Haque, Abdullah‐Al‐Jubayer, Md. Faruk Hasan, F. M. Ali Haydar, Md. Khalekuzzaman, Md. Torequl Islam, Sohel Hasan   +19 more
wiley   +1 more source

Linezolid-induced black hairy tongue: a case report

Journal of Medical Case Reports, 2013
Introduction Linezolid-induced black hairy tongue has been rarely reported. The purpose of this paper is to report a case of linezolid-induced black hairy tongue and review the literature.
Khasawneh Faisal Abdullah, Moti Dereje Fikremariam, Zorek Joseph Anthony   +2 more
doaj   +1 more source

A prospective one-year microbiologic survey of combined pneumonia and respiratory failure [PDF]

, 2017
Background: Pneumonia and respiratory failure are common problems in the intensive care unit (ICU) setting, often occurring together. The relative prevalence of pneumonia types (community acquired, hospital acquired, ventilator associated) and causative ...
Fisher, Kristen, Juang, Paul, Kollef, Marin H, Micek, Scott T, Trupka, Tracy   +4 more
core   +2 more sources

Recurrent Pneumothorax With Bronchopleural Fistula in Primary Multidrug‐Resistant Pulmonary Tuberculosis: A Challenging Case

Respirology Case Reports, Volume 14, Issue 5, May 2026.
A 41‐year‐old man with primary multidrug‐resistant pulmonary tuberculosis (MDR‐TB) developed recurrent pneumothorax and a bronchopleural fistula (BPF). Despite persistent air leak (PAL) after initial video‐assisted thoracoscopic surgery (VATS), definitive open thoracotomy with decortication and fistula repair led to sustained lung re‐expansion.
Primawati, Winariani Koesoemoprodjo, Mohamad Rizki   +2 more
wiley   +1 more source

A new oxazolidinone antimicrobial [PDF]

, 2014
Purpose. The mechanism of action, pharmacokinetics, pharmacodynamics, and clinical efficacy and safety of an investigational second-generation oxazolidinone are reviewed. Summary. Tedizolid is a protein synthesis inhibitor in clinical development for the
Childs, Lindsay M,, Kisgen, Jamie J., Mansour, Hanine, Unger, Nathan R.   +3 more
core   +1 more source

Growth Differentiation Factor‐15 Could Predict Decreased Hemoglobin in Tuberculosis Treated With Linezolid‐Containing Regimen

The Clinical Respiratory Journal, Volume 20, Issue 5, May 2026.
Baseline GDF‐15 predicts linezolid‐induced myelosuppression in rifampicin‐resistant tuberculosis. Patients with higher pretreatment GDF‐15 (> 950 pg/mL) were more likely to develop significant hemoglobin decline during therapy. Measuring GDF‐15 before treatment may help identify high‐risk patients and guide safer, personalized linezolid use.
Amaylia Oehadian, Prayudi Santoso, Delita Prihatni, Andini Kartikasari, Ida Parwati, Diah Handayani, Thomas Handoyo, Noorwati Sutandiyo, Bachti Alisjahbana, Dick Menzies, Rovina Ruslami   +10 more
wiley   +1 more source

Effect of daptomycin and vancomycin on Staphylococcus epidermidis biofilms: An in vitro assessment using fluorescence in situ hybridization [PDF]

, 2019
Colonization of in-dwelling catheters by microbial biofilms is a major concern in patient health eventually leading to catheter-related blood stream infections.
Affeld, Klaus, Gabel, Grischa, Gebhardt, M., Goubergrits, Leonid, Kertzscher, Ulrich, Kikhney, Judith, Kursawe, Laura, Moter, Annette, Petrich, A., Schmidt, Julia, Sutrave, Smita, Wiessner, Alexandra   +11 more
core   +1 more source

Allium‐Derived Compounds Against Multidrug‐Resistant Bacteria: Antibacterial Activity and Synergistic Effects

ChemMedChem, Volume 21, Issue 8, 28 April 2026.
This study evaluates four compounds derived from the genus Allium against 330 multidrug‐resistant bacteria. Propyl‐propane‐thiosulfonate (PTSO) exhibits the highest activity, particularly against Gram‐positive strains, while Gram‐negative bacteria are less affected.
Antonio Sorlózano‐Puerto, Yariel Figueroa‐Vega, Pablo Martín‐Valenzuela, José Manuel de la Torre‐Ramírez, Alberto Baños, José Gutiérrez‐Fernández   +5 more
wiley   +1 more source

N-TERMINAL PROCESSING OF RIBOSOMAL PROTEIN L27 IN STAPHYLOCOCCUS AUREUS [PDF]

, 2012
The bacterial ribosome is essential to cell growth yet little is known about how its proteins attain their mature structures. Recent studies indicate that certain Staphlyococcus aureus bacteriophage protein sequences contain specific sites that may be ...
Caufield, J. Harry
core   +1 more source