Results 161 to 170 of about 8,531 (253)

Bridging research, policy, and practice: Advancing evidence‐informed approaches for dementia care and prevention: An expert review by the Health Policy Professional Interest Area from ISTAART

open access: yesAlzheimer's &Dementia: Behavior &Socioeconomics of Aging, Volume 2, Issue 2, June 2026.
Abstract Bridging dementia research and policy remains a global challenge, with gaps in governance, capacity, data infrastructure, and contextual fit limiting the development and implementation of effective national dementia plans. To inform this issue, the Health Policy Professional Interest Area of the International Society to Advance Alzheimer's ...
Juliana Souza‐Talarico   +17 more
wiley   +1 more source

Mitigating disparities in diagnosis of dementia

open access: yesAlzheimer's &Dementia: Behavior &Socioeconomics of Aging, Volume 2, Issue 2, June 2026.
Abstract The field of Alzheimer's disease and related dementias (AD/ADRD) is undergoing a transformative shift with a better understanding of disease biology, biomarker‐based diagnostics, and disease‐modifying therapies. Yet, these advancements risk exacerbating existing disparities in diagnosis and care.
Lycia Tramujas Vasconcellos Neumann   +36 more
wiley   +1 more source

Cohort profile: a community‐based prospective cohort study of Alzheimer's disease and related dementias in the Democratic Republic of Congo

open access: yesAlzheimer's &Dementia: Behavior &Socioeconomics of Aging, Volume 2, Issue 2, June 2026.
Abstract INTRODUCTION The Étude du Vieillissement Cognitif et de Démence en République Démocratique du Congo (EVCD‐RDC) launched in 2024 to investigate socio‐environmental and biological determinants of dementia in Kinshasa. METHODS The study recruited 1000 adults aged ≥65 years across four diagnostic groups – cognitively unimpaired (CU), mild ...
Jean Ikanga   +24 more
wiley   +1 more source

Cross‐sectional associations of migration‐related indicators and research attitudes in underrepresented populations being recruited for a preclinical Alzheimer's disease trial

open access: yesAlzheimer's &Dementia: Behavior &Socioeconomics of Aging, Volume 2, Issue 2, June 2026.
Abstract Introduction Factors shaping research attitudes among immigrant and later‐generation adults from racial and ethnic groups underrepresented in Alzheimer's disease (AD) research remain poorly understood. We examined whether migration‐related indicators were associated with research attitudes during community outreach for a preclinical AD trial ...
Christian R. Salazar   +8 more
wiley   +1 more source

FKBP9 Enhances Colon Cancer Cell Proliferation by Inhibiting GPX4‐Mediated Ferroptosis

open access: yesCancer Medicine, Volume 15, Issue 6, June 2026.
The significance of FKBP9 as a therapeutic target in colon cancer treatment, providing new avenues for strategies aimed at sensitizing cancer cells to ferroptosis and improving patient outcomes. ABSTRACT Colorectal cancer, a major health issue worldwide, exhibits intricate molecular mechanisms that necessitate further exploration, particularly ...
Jianzhong Deng   +6 more
wiley   +1 more source

Exosomal miR‐4644 Targets SPRY3 to Promote Proliferation and Invasion of Pancreatic Cancer

open access: yesCancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Tumor‐derived exosomes (TDEs) can carry diverse genetic material that modulates pancreatic cancer (PC) proliferation and invasion. Despite this, the involvement of microRNAs (miRNAs) in TDE‐mediated tumor progression in PC remains inadequately explored. Methods Ultracentrifugation was used to isolate exosomes derived from AsPC‐1 and
Xiangyu Chu   +8 more
wiley   +1 more source

GLP‐1 Receptor Agonists in Metabolic Dysfunction‐Associated Steatotic Liver Disease: Bridging Hepatic and Cardiovascular Outcomes

open access: yesChronic Diseases and Translational Medicine, Volume 12, Issue 2, Page 85-99, June 2026.
Endogenous GLP‐1 and exogenous GLP‐1 RAs activate GLP‐1R‐expressing vagal afferents in the portal vein, projecting to the nucleus tractus solitarius (NTS). This input engages brainstem–hypothalamic circuits that regulate metabolic homeostasis. Hypothalamic efferent vagal output to the liver suppresses lipogenesis, enhances triglyceride export, and ...
Gabriel Amorim Moreira Alves   +8 more
wiley   +1 more source

“Diagnostic Performance of Artificial Intelligence in Evaluating Tricuspid Regurgitation: A Systematic Review and Meta‐Analysis”

open access: yesClinical Cardiology, Volume 49, Issue 6, June 2026.
Artificial intelligence demonstrates strong diagnostic accuracy for detecting tricuspid regurgitation, particularly with echocardiography‐based models. Despite promising performance, substantial heterogeneity and limited external validation highlight the need for prospective, multicenter studies before routine clinical implementation.
Pooya Eini   +3 more
wiley   +1 more source

The Silent Link: Exploring the Impact of Periodontal Diseases on Head and Neck Carcinogenesis

open access: yesClinical and Experimental Dental Research, Volume 12, Issue 3, June 2026.
ABSTRACT Objectives Oral dysbiosis can accelerate the progression of head and neck squamous cell carcinoma (HNSCC) by fostering a pro‐inflammatory, immunosuppressive, and metabolically altered environment. This narrative review examines the relationships between periodontitis‐associated bacteria and HNSCC, focusing on their impact on oncogenic pathways,
Yashmin Afshar, Nima Rezaei
wiley   +1 more source

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