Results 41 to 50 of about 6,712,199 (326)
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
Diphthamide synthesis is linked to the eEF2‐client chaperone machinery
FEBS Letters, EarlyView.The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr +4 more
wiley +1 more source
Linked open government data: lessons from Data.gov.uk [PDF]
, 2012 The movement to publish government data is an opportunity to populate the linked data Web with data of good provenance. The benefits range from transparency to public service improvement, citizen engagement to the creation of social and economic value ...
Berners-Lee, Tim +6 more
core +1 more source
Visualization of typed links in Linked Data
Mitteilungen der Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare, 2017 The main subject of the work is the visualization of typed links in Linked Data. The academic subjects relevant to the paper in general are the Semantic Web, the Web of Data and information visualization. The Semantic Web, invented by Tim Berners-Lee in 2001, was announced as an extension to the World Wide Web (Web 2.0).
openaire +5 more sources
Linked Data and Linked APIs: Similarities, Differences, and Challenges [PDF]
, 2015 In an often retweeted Twitter post, entrepreneur and software architect Inge Henriksen described the relation of Web 1.0 to Web 3.0 as: “Web 1.0 connected humans with machines. Web 2.0 connected humans with humans. Web 3.0 connects machines with machines.” On the one hand, an incredible amount of valuable data is described by billions of triples ...
Verborgh, Ruben +3 more
openaire +3 more sources
Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones
FEBS Letters, EarlyView.Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley +1 more source
Cataloguing in the open - the disintegration and distribution of the record
JLIS.it, 2013 As part of a strategic investment in openness the Swedish National Library has released the National Bibliography and accompanying authority file as open data with a Creative Commons Zero license effectively putting it in the public domain.
Martin Malmsten
doaj +1 more source
Local Type Checking for Linked Data Consumers [PDF]
, 2013 The Web of Linked Data is the cumulation of over a decade of work by the Web standards community in their effort to make data more Web-like. We provide an introduction to the Web of Linked Data from the perspective of a Web developer that would like to ...
Ciobanu, Gabriel +2 more
core +3 more sources
, 2016 Linked Data opens up structured data from databases to be searched and queried via the web, and a geographic element is increasingly being used to link to those data. This book helps you understand how to organize and describe data that includes geographic content and how to publish it as Linked Data for the Semantic Web, as well as explaining the ...
Hart, Glen, Dolbear, Catherine
openaire +4 more sources