Results 41 to 50 of about 4,098,264 (291)

RECONSTITUTION OF ALLOPHYCOCYANIN FROM Mastigocladus laminosus WITH ISOLATED LINKER POLYPEPTIDE [PDF]

open access: yes, 1993
The core linker polypeptide Lc 8.9 was isolated from Mastigocladus laminosus and purified on a preparative scale. A method for the reconstitution of allophycocyanin (AP)—linker complexes from isolated polypeptides was developed. The complex (αAP(βAP)3 Lc
Gottschalk, Lothar   +2 more
core   +1 more source

Linker-mediated self-assembly of mobile DNA-coated colloids

open access: yes, 2020
Developing construction methods of materials tailored for given applications with absolute control over building block placement poses an immense challenge.
Ciamarra, Massimo Pica   +3 more
core   +1 more source

ENERGY TRANSFER IN TRIMERIC C-PHYCOCYANIN STUDIED BY PICOSECOND FLUORESCENCE KINETICS [PDF]

open access: yes, 1986
The excited state kinetics of trimeric C-phycocyanin from Mastigocladus laminosus has been measured as a function of the emission and excitation wavelength by the single-photon timing technique with picosecond resolution and simultaneous data analysis. A
Holzwarth, A. R.   +3 more
core   +1 more source

Vapor-phase linker exchange of metal-organic frameworks

open access: yesScience Advances, 2020
A solvent-free strategy of vapor-phase linker exchange is developed for postsynthetic modification of metal-organic frameworks. Metal-organic frameworks (MOFs) have been attracting intensive attention because of their commendable potential in many ...
Wufeng Wu   +5 more
semanticscholar   +1 more source

Temperature-sensitive protein–DNA dimerizers [PDF]

open access: yes, 2005
Programmable DNA-binding polyamides coupled to short peptides have led to the creation of synthetic artificial transcription factors. A hairpin polyamide-YPWM tetrapeptide conjugate facilitates the binding of a natural transcription factor Exd to an ...
Ansari, Aseem Z.   +6 more
core   +1 more source

Antibody-drug conjugates: recent advances in conjugation and linker chemistries

open access: yesProtein & Cell, 2016
The antibody-drug conjugate (ADC), a humanized or human monoclonal antibody conjugated with highly cytotoxic small molecules (payloads) through chemical linkers, is a novel therapeutic format and has great potential to make a paradigm shift in cancer ...
K. Tsuchikama, Z. An
semanticscholar   +1 more source

iFLinkC: an iterative functional linker cloning strategy for the combinatorial assembly and recombination of linker peptides with functional domains

open access: yesNucleic Acids Research, 2020
Recent years have witnessed increasing efforts to engineer artificial biological functions through recombination of modular-organized toolboxes of protein scaffolds and parts.
Alexander Gräwe   +3 more
semanticscholar   +1 more source

Acid-Labile Traceless Click Linker for Protein Transduction [PDF]

open access: yes, 2012
Intracellular delivery of active proteins presents an interesting approach in research and therapy. We created a protein transduction shuttle based on a new traceless click linker that combines the advantages of click reactions with implementation of ...
Bachelder E. M.   +21 more
core   +1 more source

Antibody–Drug Conjugates: The Last Decade

open access: yesPharmaceuticals, 2020
An armed antibody (antibody–drug conjugate or ADC) is a vectorized chemotherapy, which results from the grafting of a cytotoxic agent onto a monoclonal antibody via a judiciously constructed spacer arm.
Nicolas Joubert   +3 more
doaj   +1 more source

Highly Mutable Linker Regions Regulate HIV-1 Rev Function and Stability. [PDF]

open access: yes, 2019
HIV-1 Rev is an essential viral regulatory protein that facilitates the nuclear export of intron-containing viral mRNAs. It is organized into structured, functionally well-characterized motifs joined by less understood linker regions.
Fernandes, Jason D   +4 more
core   +3 more sources

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