Results 211 to 220 of about 170,550 (343)
Electrical Stimulation Directs Formation of Perfused Vasculature in Engineered Tissues
Electrical stimulation (ESTIM) enhances vasculature formation in engineered human tissues. In 3D endothelial‐fibroblast constructs, conditioning with ESTIM promotes the formation of dense and highly branched networks that rapidly anastomose with mouse vasculature when implanted in vivo. Vessels formed under ESTIM are importantly functionally perfusable.
Katarzyna A. Grzelak +6 more
wiley +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
The Emerging Parkinson's Disease Oxylipin‐Ome
ABSTRACT Parkinson Disease (PD) is increasingly considered a proteinopathy and lipidopathy. This proteinopathy+lipidopathy paradigm has been further refined to a fatty acid (FA)‐opathy, centering dysregulated FA metabolism as fundamental in PD lipid dysfunction.
Julia C. Kelliher, Saranna Fanning
wiley +1 more source
ABSTRACT Lipids are important for metabolic processes, mainly cytokine regulation in the skeletal muscle and liver. Considering the soybean oil concentration, a weighted gene co‐expression network analysis (WGCNA) was used to perform an integrative analysis in skeletal muscle and liver tissues.
Fernanda Nery Ciconello +9 more
wiley +1 more source
Cerrado oil is richer in MUFA and antioxidant compounds, while Xingu oil shows higher SFA and enhanced oxidative stability, reinforcing the potential of pequi oil as a sustainable bioactive ingredient. ABSTRACT Pequi ( Caryocar brasiliense ) is a native fruit widely distributed in Brazilian biomes, specially in Cerrado, known for its high oil yield and
Dhayna O. Sobral +8 more
wiley +1 more source
<i>Chaetopterus</i> Luciferase: A Promising Tool for Online Lipid Peroxidation Detection. [PDF]
Shcheglov AS +6 more
europepmc +1 more source
ABSTRACT Advanced lipid profiling relies on liquid chromatography–tandem mass spectrometry (LC–MS/MS), but long analysis times remain a challenge. Supercritical fluid chromatography (SFC)–MS/MS using supercritical carbon dioxide offers a faster and more environmentally friendly alternative.
Ryosuke Aoki +6 more
wiley +1 more source
Fruit Seeds with Functional Applications: From Food Waste to Potential Uses. [PDF]
Fernandes DS +9 more
europepmc +1 more source
The essential oil and major compounds from Piper cyrtopodon exhibit potent, long‐lasting repellent activity against Aedes aegypti mosquitoes, combined with low cytotoxicity and favorable molecular docking interactions with odorant‐binding proteins. These findings highlight its potential for the development of alternative products for bite prevention ...
Maria L. L. da Costa +7 more
wiley +1 more source

