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Adipocyte response to conjugated linoleic acid
Obesity Research & Clinical Practice, 2013Conjugated linoleic acid (CLA), which is a generic term to describe isomers of octadecadienoic acid, has been reported to exert various beneficial physiological effects. Accumulating data show that CLA, especially trans10, cis12 (t10, c12)-CLA, has a potent body fat-reducing effect, which is prominent in mice and to a lesser extent rats.
Masao, Yamasaki, Teruyoshi, Yanagita
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Conjugated Linoleic Acid and Bone Biology
Journal of the American College of Nutrition, 2000Osteoporosis, osteoarthritis and inflammatory joint disease afflict millions of people worldwide. Inflammatory cytokines inhibit chondrocyte proliferation and induce cartilage degradation for which part of the response is mediated by PGE2. Excess production of PGE2 is linked to osteoporosis and arthritis and is associated with bone and proteoglycan ...
B A, Watkins, M F, Seifert
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Conjugated Linoleic Acid in Cancer Therapy
Current Drug DeliveryConjugated Linoleic Acid (CLA) is a polyunsaturated dietary fatty acid. Probiotics can biohydrogenate CLA with multiple health benefits, especially in cancer treatment. <i>In vitro, in vivo</i>, and clinical studies have confirmed CLA isomers to possess anti-cancer activity.
Jeneesha George, Asit Ranjan Ghosh
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