Results 21 to 30 of about 1,182 (107)

Perfil hematólogico e características das fezes de equinos consumindo dietas hiperlipidêmicas Blood profile and characteristics of the feces of horses fed with high fat diets

Ciência Rural, 2009
Objetivou-se avaliar os parâmetros sanguíneos, o consumo de matéria seca e as características fecais de equinos alimentados com dietas hiperlipidêmicas.
Fernanda Nascimento Godoi, Fernando Queiroz Almeida, Giuliano Aragonez Guarienti, Juliano Martins Santiago, Daniel Guedes Júnior, Yzabella Campos Nogueira, Lucas Santiago Brasileiro   +6 more
doaj   +1 more source

Deucravacitinib, an Oral, Selective, Allosteric Tyrosine Kinase 2 Inhibitor, in Asian Patients With Moderate to Severe Psoriasis: Improvements in Patient‐Reported Outcomes in a Randomized Trial

The Journal of Dermatology, Volume 52, Issue 9, Page 1360-1367, September 2025.
ABSTRACT POETYK PSO‐3, a 52‐week, double‐blind, phase 3 study, evaluated the efficacy and safety of deucravacitinib, an oral, selective, allosteric tyrosine kinase 2 inhibitor, in adult patients with moderate to severe plaque psoriasis in mainland China, Taiwan, and South Korea.
Jianzhong Zhang, Yangfeng Ding, Ping Wang, Linfeng Li, Weili Pan, Yan Lu, Hao Cheng, Xian Jiang, Ji‐Chen Ho, Shuping Guo, Seong Jun Seo, Linda Stein Gold, Andrew Blauvelt, Joe Zhuo, Yichen Zhong, Brandon Becker, Leona Liu, Subhashis Banerjee, Diamant Thaçi   +18 more
wiley   +1 more source

Qualidade da carne do músculo longissimus dorsi de novilhos superjovens Aberdeen Angus de biótipo pequeno e médio abatidos com o mesmo estágio de acabamento na carcaça - doi: 10.4025/actascianimsci.v33i2.10746

Acta Scientiarum: Animal Sciences, 2011
O objetivo deste trabalho foi verificar a influência do biótipo pequeno e médio de novilhos Aberdeen Angus superjovens na composição da carne do longissimus dorsi (LD). Foram utilizadas secções do LD de oito novilhos com biótipo pequeno e dez com biótipo
Miguelangelo Ziegler Arboitte, Ivan Luis Brondani, Francisco Carlos Deschamps, Fabiano Cleber Bertoldi, Dari Celestino Alves Filho, Luciane Segabinazzi Rumpel   +5 more
doaj   +1 more source

Deep Learning Reveals Liver MRI Features Associated With PNPLA3 I148M in Steatotic Liver Disease

Liver International, Volume 45, Issue 7, July 2025.
ABSTRACT Background Steatotic liver disease (SLD) is the most common liver disease worldwide, affecting 30% of the global population. It is strongly associated with the interplay of genetic and lifestyle‐related risk factors. The genetic variant accounting for the largest fraction of SLD heritability is PNPLA3 I148M, which is carried by 23% of the ...
Yazhou Chen, Benjamin P. M. Laevens, Teresa Lemainque, Gustav Anton Müller‐Franzes, Tobias Seibel, Carola Dlugosch, Jan Clusmann, Paul‐Henry Koop, Rongpeng Gong, Yuanyuan Liu, Niharika Jakhar, Feng Cao, Simon Schophaus, Thriveni Basavanapura Raju, Anastasia Artemis Raptis, Felix van Haag, Joel Joy, Rohit Loomba, Luca Valenti, Jakob Nikolas Kather, Titus J. Brinker, Moritz Herzog, Ivan G. Costa, Diego Hernando, Kai Markus Schneider, Daniel Truhn, Carolin V. Schneider   +26 more
wiley   +1 more source

Fatty acid composition of commercially important fish from Brazil Composição em ácidos graxos de peixes comercialmente importantes do Brasil

Scientia Agricola, 1993
Total fat and fatty acid composition of seven fresh-water and nine marine fish commercially important in Brazil were determined. Palmitic acid was the predominant saturated fatty acid in both freshwater and marine fish.
L.E. Gutierrez, R.C.M. da Silva
doaj   +1 more source

The Lipidomic Profile Discriminates Between MASLD and MetALD

Alimentary Pharmacology &Therapeutics, Volume 61, Issue 8, Page 1357-1371, April 2025.
HDL‐centric lipidomic biomarkers, particularly within large and medium HDL subfractions, distinguish metabolic dysfunction and alcohol‐related liver disease from metabolic dysfunction‐associated steatotic liver disease, suggesting potential biomarkers for clinical differentiation.
Kai Markus Schneider, Feng Cao, Helen Ye Rim Huang, Lanlan Chen, Yazhou Chen, Rongpeng Gong, Anastasia Raptis, Kate Townsend Creasy, Jan Clusmann, Felix van Haag, Paul‐Henry Koop, Adrien Guillot, Tom Luedde, Rohit Loomba, Sven Francque, Carolin Victoria Schneider   +15 more
wiley   +1 more source

Targeting PNPLA3 to Treat MASH and MASH Related Fibrosis and Cirrhosis

Liver International, Volume 45, Issue 4, April 2025.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) is caused by metabolic triggers and genetic predisposition. Among the genetic MASLD risk variants identified today, the common PNPLA3 148M variant exerts the largest effect size of MASLD heritability.
Daniel Lindén, Gregory Tesz, Rohit Loomba   +2 more
wiley   +1 more source

Effects of Pemafibrate on Serum Carnitine and Plasma Myostatin in Patients With Metabolic Dysfunction Associated Steatotic Liver Disease

JCSM Communications, Volume 8, Issue 1, January/June 2025.
ABSTRACT Background Pemafibrate, a selective peroxisome proliferator‐activated receptor alpha (PPARα) modulator (SPPARMα), has positive effects on liver‐related markers (e.g., liver stiffness determined by magnetic resonance elastography and alanine aminotransferase) in the PEMA‐FL study in patients with metabolic dysfunction‐associated steatotic liver
Ryohei Tanigawa, Atsushi Nakajima, Yuichiro Eguchi, Hirokazu Takahashi, Rohit Loomba, Hideki Suganami, Masaya Tanahashi, Hidenori Arai   +7 more
wiley   +1 more source

Prolonged ruxolitinib cream treatment for vitiligo among patients with no or limited response in the first 6 months

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Albert Wolkerstorfer, Melinda J. Gooderham, Michael Sebastian, David Rosmarin, Andrew Blauvelt, Maryam Shayesteh Alam, Jacek Zdybski, Shaoceng Wei, Deanna Kornacki, Thierry Passeron, John E. Harris   +10 more
wiley   +1 more source

Optimizing maintenance therapy in responders to abrocitinib induction: A post hoc analysis of JADE REGIMEN

Journal of the European Academy of Dermatology and Venereology, Volume 38, Issue 11, Page 2130-2138, November 2024.
Abstract Background Treatment optimization may require dosing flexibility. The Phase 3 JADE REGIMEN trial (NCT03627767) evaluated maintenance of abrocitinib 200 mg‐induced response in patients with moderate‐to‐severe atopic dermatitis (AD) randomly assigned to subsequent maintenance with continuous‐dose abrocitinib (200 mg), reduced‐dose abrocitinib ...
J. P. Thyssen, J. I. Silverberg, J. Ruano, A. Blauvelt, W. Gubelin, E. L. Simpson, S. Weidinger, H. Valdez, K. K. Terry, P. Biswas, E. Güler, C. Feeney   +11 more
wiley   +1 more source