Results 131 to 140 of about 890,691 (262)
Manipulation of lipid rafts in neuronal cells [PDF]
, 2010 Lipid rafts are specialized plasma membrane micro-domains highly enriched in cholesterol, sphingolipids and glycosylphosphatidylinositol (GPI) anchored proteins.
Eckert, Gunter P.
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Lipid Metabolism Regulation in TAM: From Cellular Reprogramming to Systemic Metabolic Networks
Zhongliu Fangzhi YanjiuTumor-associated macrophages (TAMs) have become the core hub connecting the local microenvironment and system metabolism through lipid metabolism reprogramming.
Yuxuan LI, Yunhui LI, Huan REN
doaj +1 more source
Reply to McCarthy et al.: Lipid-Laden Macrophages Are Not Diagnostic of Pulmonary Alveolar Proteinosis Syndrome and Can Indicate Lung Injury. [PDF]
Am J Respir Crit Care Med, 2020 Israel AK, McGraw MD, Agrawal T.
europepmc +1 more source
Advanced Science, EarlyView.Schematic diagram showing compressive stress triggers glycolytic reprogramming and lactate accumulation in macrophages. Lactate mediates TRAF6 lactylation at K171/K180 dual sites, which enhances its K63‐linked ubiquitination to activate the NF‑κB pathway and promote M1 polarization. This cascade drives orthodontic tooth movement (OTM) and alveolar bone
Xinyi He +9 more
wiley +1 more source
Role of Ro60/RNYs complex in lipid-laden macrophages
, 2020 Ro60, protéine de liaison à l'ARN qui s'associe aux YRNAs pour former le complexe RoRNP, est une cible de la réponse immunitaire chez les patients atteints de lupus érythémateux disséminé (LED) et du syndrome de Sjögren (SS).
Fazio, Sofia
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Lipoid Pneumonia: Siphoning of Gasoline
Journal of Association of Pulmonologist of Tamil NaduLipoid pneumonia is a rare condition that accounts for 1%–2.5% of all pneumonia. There are two types – exogenous and endogenous. In recent days, exogenous lipoid pneumonia has been on an increasing trend due to the exponential use of vaping.
Keerthi A. Prakash +2 more
doaj +1 more source
Adipocytes Secrete Lipid-Laden Exosomes and Influence Local Macrophage Behavior
, 2020 To meet the body’s metabolic needs, adipocytes release fatty acids and glycerol through the action of neutral lipases. Lipids are also key local regulators of immune function. During obesity, triglycerides accumulate in adipose tissue macrophages and this accumulation is associated with systemic metabolic complications including insulin resistance and ...
openaire +2 more sources
Deconstruction of Human Age‐Related Cataract Capsules Defines Aging
Advanced Science, EarlyView.We generate a comprehensive atlas of age‐related cataracts (ARC) at a single‐cell resolution, encompassing three disease states—mild cataract group (Mild), severe cortical cataract group (Severe_C), and severe nuclear cataract group (Severe_N). We find that ARC involves seven distinct lens capsule cell types, with notable differences in cellular ...
Qiaomei Tang +9 more
wiley +1 more source
Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery
Advanced Science, EarlyView.Systematic engineering of hydrophobic tail architecture in vitamin B5‐derived ionizable lipids establishes a comprehensive structure–activity relationship framework for mRNA delivery. Combined lipidtail and formulation optimization identifies TM1‐OPT3‐C, a lipid nanoparticle platform that improves efficacy–safety balance through efficient mRNA delivery,
Seo‐Hyeon Bae +27 more
wiley +1 more source
Chemiluminescence of asbestos-activated macrophages [PDF]
, 1984 Chemiluminescence, a measure of reactive oxygen release by phagocytes, was compared in peritoneal exudate macrophages elicited with chrysotile asbestos, Corynebacterium parvum and saline. Chrysotile asbestos- and C.
Cullen, R T, Donaldson, Ken
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